| Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation EY Chi, S Krishnan, TW Randolph, JF Carpenter Pharmaceutical research 20 (9), 1325-1336, 2003 | 1744 | 2003 |
| Rational design of stable lyophilized protein formulations: some practical advice JF Carpenter, MJ Pikal, BS Chang, TW Randolph Pharmaceutical research 14 (8), 969, 1997 | 1021 | 1997 |
| Water in Carbon-Dioxide Microemulsions-An Environment for Hydrophiles Including Proteins KP Johnston, KL Harrison, MJ Clarke, SM Howdle, MP Heitz, FV Bright, ... Science 271 (5249), 624-626, 1996 | 795 | 1996 |
| Hydrogen bonding between sugar and protein is responsible for inhibition of dehydration-induced protein unfolding SD Allison, B Chang, TW Randolph, JF Carpenter Archives of Biochemistry and Biophysics 365 (2), 289-298, 1999 | 707 | 1999 |
| Overlooking subvisible particles in therapeutic protein products: Gaps that may compromise product quality JF Carpenter, TW Randolph, WIM Jiskoot, DJA Crommelin, CR Middaugh, ... Journal of pharmaceutical sciences 98 (4), 1201-1205, 2008 | 637 | 2008 |
| The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperaturecontrolled shelf JA Searles, JF Carpenter, TW Randolph Journal of pharmaceutical sciences 90 (7), 860-871, 2001 | 490 | 2001 |
| Rational design of stable lyophilized protein formulations: theory and practice JF Carpenter, BS Chang, W Garzon-Rodriguez, TW Randolph Rational Design of Stable Protein Formulations, 109-133, 2002 | 435 | 2002 |
| Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colonystimulating factor EY Chi, S Krishnan, BS Kendrick, BS Chang, JF Carpenter, TW Randolph Protein science 12 (5), 903-913, 2009 | 432 | 2009 |
| Tween protects recombinant human growth hormone against agitationinduced damage via hydrophobic interactions NB Bam, JL Cleland, J Yang, MC Manning, JF Carpenter, RF Kelley, ... Journal of pharmaceutical sciences 87 (12), 1554-1559, 1998 | 388 | 1998 |
| Annealing to optimize the primary drying rate, reduce freezinginduced drying rate heterogeneity, and determine Tg′ in pharmaceutical lyophilization JA Searles, JF Carpenter, TW Randolph Journal of pharmaceutical sciences 90 (7), 872-887, 2001 | 383 | 2001 |
| Effects of Tween 20® and Tween 80® on the stability of Albutropin during agitation DK Chou, R Krishnamurthy, TW Randolph, JF Carpenter, MC Manning Journal of pharmaceutical sciences 94 (6), 1368-1381, 2005 | 375 | 2005 |
| Enzymatic catalysis in a supercritical fluid TW Randolph, HW Blanch, JM Prausnitz, CR Wilke Biotechnology letters 7 (5), 325-328, 1985 | 349 | 1985 |
| Sub-micrometer-sized biodegradable particles of poly (L-lactic acid) via the gas antisolvent spray precipitation process TW Randolph, AD Randolph, M Mebes, S Yeung Biotechnology Progress 9 (4), 429-435, 1993 | 344 | 1993 |
| Silicone oil-and agitation-induced aggregation of a monoclonal antibody in aqueous solution R Thirumangalathu, S Krishnan, MS Ricci, DN Brems, TW Randolph, ... Journal of pharmaceutical sciences 98 (9), 3167-3181, 2009 | 319 | 2009 |
| Effect of Tween 20 on freezethawingand agitationinduced aggregation of recombinant human factor XIII L Krielgaard, LS Jones, TW Randolph, S Frokjaer, JM Flink, MC Manning, ... Journal of pharmaceutical sciences 87 (12), 1593-1603, 1998 | 295 | 1998 |
| Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release W Jiskoot, TW Randolph, DB Volkin, CR Middaugh, C Schöneich, ... Journal of pharmaceutical sciences 101 (3), 946-954, 2012 | 292 | 2012 |
| Solubilization of Pharmaceutical Substances in an Organic Solvent and Preparation of Pharmaceutical Powders Using the Same MC Manning, TW Randolph, E Shefter, RF Falk US Patent 5,981,474, 1999 | 289 | 1999 |
| Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: Role in restricted conformational mobility and compaction of native state BS Kendrick, BS Chang, T Arakawa, B Peterson, TW Randolph, ... Proceedings of the National Academy of Sciences 94 (22), 11917-11922, 1997 | 273 | 1997 |
| Sustained-release composition including amorphous polymer TW Randolph, MC Manning, RF Falk US Patent 6,613,358, 2003 | 260 | 2003 |
| Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease α-synuclein fibrillogenesis S Krishnan, Y Eva, SJ Wood, BS Kendrick, C Li, W Garzon-Rodriguez, ... Biochemistry 42 (3), 829-837, 2003 | 257 | 2003 |
Eva Y. ChiProfessor and Regents' Lecturer, Dept of Chem & Biol Eng, University of New Mexico在 unm.edu 的电子邮件经过验证
