The COMET toolkit for composing customizable genetic programs in mammalian cells PS Donahue, JW Draut, JJ Muldoon, HI Edelstein, N Bagheri, JN Leonard Nature Communications 11 (1), 1–19, 2020 | 63 | 2020 |
Macrophages employ quorum licensing to regulate collective activation JJ Muldoon, Y Chuang, N Bagheri, JN Leonard Nature Communications 11 (1), 1–14, 2020 | 51 | 2020 |
The modifier of transcription 1 (Mot1) ATPase and Spt16 histone chaperone co-regulate transcription through preinitiation complex assembly and nucleosome organization JD True*, JJ Muldoon*, MN Carver, K Poorey, SJ Shetty, S Bekiranov, ... Journal of Biological Chemistry 291 (29), 15307–15319, 2016 | 37 | 2016 |
Multiplexing engineered receptors for multiparametric evaluation of environmental ligands RM Hartfield*, KA Schwarz*, JJ Muldoon*, N Bagheri, JN Leonard ACS Synthetic Biology 6 (11), 2042–2055, 2017 | 31 | 2017 |
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes DV Foss*, JJ Muldoon*, DN Nguyen*, D Carr, SU Sahu, JM Hunsinger, ... Nature Biomedical Engineering 7, 647–660, 2023 | 30 | 2023 |
Elucidation and refinement of synthetic receptor mechanisms HI Edelstein*, PS Donahue*, JJ Muldoon, AK Kang, TB Dolberg, ... Synthetic Biology 5 (1), ysaa017, 2020 | 26 | 2020 |
Model-guided design of mammalian genetic programs JJ Muldoon, V Kandula, M Hong, PS Donahue, JD Boucher, N Bagheri, ... Science Advances 7 (8), eabe9375, 2021 | 23 | 2021 |
An evolved AAV variant enables efficient genetic engineering of murine T cells WA Nyberg*, J Ark*, A To, S Clouden, G Reeder, JJ Muldoon, JY Chung, ... Cell 186, 446–460.e19, 2023 | 20 | 2023 |
Nanofountain probe electroporation enables versatile single‐cell intracellular delivery and investigation of postpulse electropore dynamics SSP Nathamgari, N Pathak, V Lemaitre, P Mukherjee, JJ Muldoon, ... Small, 2002616, 2020 | 20 | 2020 |
Network inference performance complexity: a consequence of topological, experimental, and algorithmic determinants JJ Muldoon*, JS Yu*, MK Fassia, N Bagheri Bioinformatics 35 (18), 3421–3432, 2019 | 14 | 2019 |
GAMES: A dynamic model development workflow for rigorous characterization of synthetic genetic systems KE Dray, JJ Muldoon, NM Mangan, N Bagheri, JN Leonard ACS Synthetic Biology 11 (2), 1009–1029, 2022 | 10 | 2022 |
Building with intent: technologies and principles for engineering mammalian cell-based therapies to sense and respond JJ Muldoon*, PS Donahue*, TB Dolberg*, JN Leonard Current Opinion in Biomedical Engineering 4, 127–133, 2017 | 10 | 2017 |
Ablation of Cullin-5 in Primary Human T Cells Improves Tumor Killing and Persistence in BCMA-Targeting CAR-T Cells in a Multiple Myeloma Model S Bachl, A Talbot, C Ching, N Kale, Z Li, M Diolaiti, AP Chen, J Muldoon, ... Blood 142, 99, 2023 | 1 | 2023 |
Tracking cell-cell interactions using intercellular barcode transfer NQ Tay, T Juan, JJ Muldoon, J Eyquem, MT McManus Cancer Research 84 (6_Supplement), 6633-6633, 2024 | | 2024 |
Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection CR Chang, VS Vykunta, DB Goodman, JJ Muldoon, WA Nyberg, C Liu, ... bioRxiv, 2024.02. 06.576175, 2024 | | 2024 |
Targeted Integration of a Chimeric Antigen Receptor in Key Selected Loci in Primary Natural Killer Cells V Allain, A Rothrock, W Nyberg, J Muldoon, A To, JY Chung, C Chang, ... Blood 142, 4807, 2023 | | 2023 |
Engineered mamalian genetic circuits and methods of using the same JN Leonard, JJ Muldoon, PS Donahue US Patent App. 18/026,734, 2023 | | 2023 |
Computational Modeling of Synthetic Gene Circuits to Improve Stem Cell Differentiation M Hong, J Muldoon, J Leonard 2018 AIChE Annual Meeting, 2018 | | 2018 |
Computational Design of Synthetic Genetic Programs That Exhibit Pulse Dynamics M Hong, J Muldoon, PS Donahue, JW Draut, J Leonard 2018 AIChE Annual Meeting, 2018 | | 2018 |
Comet: A Novel Transcription Toolbox for Engineering Cellular Therapies PS Donahue, JW Draut, JJ Muldoon, JN Leonard MOLECULAR THERAPY 26 (5), 76–76, 2018 | | 2018 |