Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines W Huang, A Massouras, Y Inoue, J Peiffer, M Ràmia, AM Tarone, ... Genome research 24 (7), 1193-1208, 2014 | 629 | 2014 |
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—an emerging role for gut microbiome S MahmoudianDehkordi, M Arnold, K Nho, S Ahmad, W Jia, G Xie, ... Alzheimer's & Dementia 15 (1), 76-92, 2019 | 474 | 2019 |
Metabolic network failures in Alzheimer's disease: A biochemical road map JB Toledo, M Arnold, G Kastenmüller, R Chang, RA Baillie, X Han, ... Alzheimer's & Dementia 13 (9), 965-984, 2017 | 399 | 2017 |
Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study N Abdo, M Xia, CC Brown, O Kosyk, R Huang, S Sakamuru, YH Zhou, ... Environmental health perspectives 123 (5), 458-466, 2015 | 109 | 2015 |
An adaptive permutation approach for genome-wide association study: evaluation and recommendations for use R Che, JR Jack, AA Motsinger-Reif, CC Brown BioData mining 7, 1-13, 2014 | 104 | 2014 |
Using ToxCast™ data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure I Shah, RW Setzer, J Jack, KA Houck, RS Judson, TB Knudsen, J Liu, ... Environmental health perspectives 124 (7), 910-919, 2016 | 73 | 2016 |
Targeted metabolomics and medication classification data from participants in the ADNI1 cohort S John-Williams, C Blach, JB Toledo, DM Rotroff, S Kim, K Klavins, ... Scientific data 4 (1), 1-11, 2017 | 65 | 2017 |
Genetic heterogeneity beyond CYP2C8* 3 does not explain differential sensitivity to paclitaxel-induced neuropathy DL Hertz, S Roy, J Jack, AA Motsinger-Reif, A Drobish, LS Clark, ... Breast cancer research and treatment 145, 245-254, 2014 | 51 | 2014 |
Genetic variants in CPA6 and PRPF31 are associated with variation in response to metformin in individuals with type 2 diabetes DM Rotroff, SW Yee, K Zhou, SW Marvel, HS Shah, JR Jack, TM Havener, ... Diabetes 67 (7), 1428-1440, 2018 | 48 | 2018 |
Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes DM Rotroff, SS Pijut, SW Marvel, JR Jack, TM Havener, A Pujol, ... Clinical Pharmacology & Therapeutics 103 (4), 712-721, 2018 | 45 | 2018 |
Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines CC Brown, TM Havener, MW Medina, JR Jack, RM Krauss, HL McLeod, ... Pharmacogenomics 15 (2), 137-146, 2014 | 33 | 2014 |
Lymphoblastoid cell lines models of drug response: successes and lessons from this pharmacogenomic model J Jack, D Rotroff, A Motsinger-Reif Current molecular medicine 14 (7), 833-840, 2014 | 31 | 2014 |
Simulating quantitative cellular responses using asynchronous threshold Boolean network ensembles J Jack, JF Wambaugh, I Shah BMC systems biology 5, 1-13, 2011 | 30 | 2011 |
High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures JA Franzosa, JA Bonzo, J Jack, NC Baker, P Kothiya, RP Witek, P Hurban, ... Npj Systems Biology and Applications 7 (1), 7, 2021 | 27 | 2021 |
the Alzheimer Disease Metabolomics Consortium Altered bile acid profile associates with cognitive impairment in Alzheimer’s disease-An emerging role for gut microbiome S MahmoudianDehkordi, M Arnold, K Nho, S Ahmad, W Jia, G Xie, ... Alzheimers Dement 15 (1), 76-92, 2019 | 22 | 2019 |
Systems toxicology from genes to organs J Jack, J Wambaugh, I Shah Computational Toxicology: Volume II, 375-397, 2013 | 16 | 2013 |
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome (vol 15, pg 76, 2019) S Mahmoudiandehkordi, M Arnold, K Nho, S Ahmad, S Ahmad, W Jia, ... ALZHEIMERS & DEMENTIA 15 (4), 604-604, 2019 | 14 | 2019 |
The influence of packed cell volume versus plasma proteins on thromboelastographic variables in canine blood AM Lynch, L Ruterbories, J Jack, AA Motsinger‐Reif, R Hanel Journal of Veterinary Emergency and Critical Care 30 (4), 418-425, 2020 | 12 | 2020 |
Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics … CW McDonough, HR Warren, JR Jack, AA Motsinger‐Reif, ND Armstrong, ... Clinical Pharmacology & Therapeutics 110 (3), 723-732, 2021 | 11 | 2021 |
A comparison of DMET Plus microarray and genome-wide technologies by assessing population substructure JN Jackson, KM Long, Y He, AA Motsinger-Reif, HL McLeod, J Jack Pharmacogenetics and genomics 26 (4), 147-153, 2016 | 11 | 2016 |