Transforming growth factors α and β are essential for modeling cholangiocarcinoma desmoplasia and progression in a three-dimensional organotypic culture model MÁ Manzanares, A Usui, DJ Campbell, CI Dumur, GT Maldonado, ... The American Journal of Pathology 187 (5), 1068-1092, 2017 | 19 | 2017 |
Calreticulin exploits TGF‐β for extracellular matrix induction engineering a tissue regenerative process UM Pandya, MA Manzanares, A Tellechea, C Egbuta, J Daubriac, ... The FASEB Journal, 2020 | 17 | 2020 |
Dietary extra-virgin olive oil and corn oil differentially modulate the mRNA expression of xenobiotic-metabolizing enzymes in the liver and in the mammary gland in a rat … MÁ Manzanares, M Solanas, R Moral, R Escrich, E Vela, I Costa, ... European Journal of Cancer Prevention 24 (3), 215-222, 2015 | 16 | 2015 |
Overexpression of periostin and distinct mesothelin forms predict malignant progression in a rat cholangiocarcinoma model MÁ Manzanares, DJW Campbell, GT Maldonado, AE Sirica Hepatology Communications 2 (2), 155-172, 2018 | 11 | 2018 |
Dietary lipids differentially modulate the initiation of experimental breast carcinogenesis through their influence on hepatic xenobiotic metabolism and DNA damage in the … MÁ Manzanares, C de Miguel, MCR de Villa, RM Santella, E Escrich, ... The Journal of Nutritional Biochemistry 43, 68-77, 2017 | 10 | 2017 |
Ontogeny of the Major Xenobiotic‐Metabolizing Enzymes Expression and the Dietary Lipids Modulatory Effect in the Rat Dimethylbenz (a) anthracene‐Induced Breast Cancer Model MA Manzanares, M Solanas, R Moral, R Escrich, E Vela, E Escrich Journal of Biochemical and Molecular Toxicology 28 (12), 539-548, 2014 | 6 | 2014 |
SpliceCore (R) a platform for identifying aberrant alternative splicing in triple negative breast cancer for novel therapeutic development MA Manzanares, D Priyanka, K Anderson, V Frederick, A Geier, A Casill, ... MOLECULAR CANCER THERAPEUTICS 20 (12), 2021 | 1 | 2021 |
Development and validation of AI/ML derived splice-switching oligonucleotides AD Fronk, MA Manzanares, P Zheng, A Geier, K Anderson, S Stanton, ... Molecular Systems Biology, 1-26, 2024 | | 2024 |
Novel splicing-derived neoantigen in triple negative breast cancer uncovered by SpliceIO™ a robust platform for the discovery and validation of disease-specific immunotherapies N Williams, MA Manzanares, K Anderson, H Zunrut, S Gera, N Habib, ... Cancer Research 84 (6_Supplement), 5894-5894, 2024 | | 2024 |
Novel immune-therapeutic target for lung cancer uncovered by SpliceIO™, an innovative platform that identifies disease-specific alternative splicing MA Manzanares, K Anderson, H Zumrut, S Gera, N Habib, N Williams, ... Cancer Research 84 (6_Supplement), 5888-5888, 2024 | | 2024 |
Calreticulin accelerates corneal wound closure and mitigates fibrosis: Potential therapeutic applications S Mishra, MA Manzanares, J Prater, D Culp, LI Gold Journal of Cellular and Molecular Medicine, 2024 | | 2024 |
SpliceIO: A robust platform for the discovery and validation of splicing-derived neoantigens. G Arun, K Anderson, MA Manzanares, S Gera, H Zumrut, S Smith, T Floyd, ... Journal of Clinical Oncology 41 (16_suppl), 2581-2581, 2023 | | 2023 |
Computational discovery and experimental validation of splicing-derived neoantigens HE Zumrut, K Anderson, M Manzanares, S Smith, S Gera, N Habib, ... Cancer Research 83 (7_Supplement), 448-448, 2023 | | 2023 |
Development and validation of an AI/ML platform for the discovery of splice-switching oligonucleotide targets AD Fronk, MA Manzanares, P Zheng, A Geier, K Anderson, V Frederick, ... bioRxiv, 2022.10. 14.512313, 2022 | | 2022 |
SpliceIO™ a novel AI platform for the discovery of splicing-derived immunotherapeutic targets M Manzanares, H Zumrut, S Gera, A Casill, K Anderson, A Geier, ... European Journal of Cancer 174, S126, 2022 | | 2022 |
SpliceCore® a novel ML tool for identifying disease-specific alternative splicing uncovered a promising therapeutic target for triple negative breast cancer MA Manzanares, A Casill, K Anderson, P Dhingra, V Frederick, A Geier, ... Cancer Research 82 (12_Supplement), 1873-1873, 2022 | | 2022 |
Abstract P5-17-11: Novel therapeutic target for triple negative breast cancer uncovered by SpliceCore® an innovative platform that identifies disease-specific alternative splicing MA Manzanares, P Dhingra, K Anderson, V Frederick, A Geier, A Casill, ... Cancer Research 82 (4_Supplement), P5-17-11-P5-17-11, 2022 | | 2022 |
Novel therapeutic target for triple negative breast cancer uncovered by SpliceCore (R) an innovative platform that identifies disease-specific alternative splicing MA Manzanares, P Dhingra, K Anderson, V Frederick, A Geier, A Casill, ... CANCER RESEARCH 82 (4), 2022 | | 2022 |
Abstract P170: SpliceCore® a platform for identifying aberrant alternative splicing in triple negative breast cancer for novel therapeutic development MA Manzanares, D Priyanka, K Anderson, V Frederick, A Geier, A Casill, ... Molecular Cancer Therapeutics 20 (12_Supplement), P170-P170, 2021 | | 2021 |
Calreticulin exploits TGF-beta for extracellular matrix induction engineering a tissue regenerative process (vol 34, pg 15849, 2020) UM Pandya, MA Manzanares, A Tellechea, C Egbuta, J Daubriac, ... FASEB JOURNAL 35 (4), 2021 | | 2021 |