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Miguel A. Manzanares, Ph.D.
Miguel A. Manzanares, Ph.D.
Envisagenics - Principal Scientist, Biology Dept.
Verified email at envisagenics.com - Homepage
Title
Cited by
Cited by
Year
Transforming growth factors α and β are essential for modeling cholangiocarcinoma desmoplasia and progression in a three-dimensional organotypic culture model
MÁ Manzanares, A Usui, DJ Campbell, CI Dumur, GT Maldonado, ...
The American Journal of Pathology 187 (5), 1068-1092, 2017
192017
Calreticulin exploits TGF‐β for extracellular matrix induction engineering a tissue regenerative process
UM Pandya, MA Manzanares, A Tellechea, C Egbuta, J Daubriac, ...
The FASEB Journal, 2020
172020
Dietary extra-virgin olive oil and corn oil differentially modulate the mRNA expression of xenobiotic-metabolizing enzymes in the liver and in the mammary gland in a rat …
MÁ Manzanares, M Solanas, R Moral, R Escrich, E Vela, I Costa, ...
European Journal of Cancer Prevention 24 (3), 215-222, 2015
162015
Overexpression of periostin and distinct mesothelin forms predict malignant progression in a rat cholangiocarcinoma model
MÁ Manzanares, DJW Campbell, GT Maldonado, AE Sirica
Hepatology Communications 2 (2), 155-172, 2018
112018
Dietary lipids differentially modulate the initiation of experimental breast carcinogenesis through their influence on hepatic xenobiotic metabolism and DNA damage in the …
MÁ Manzanares, C de Miguel, MCR de Villa, RM Santella, E Escrich, ...
The Journal of Nutritional Biochemistry 43, 68-77, 2017
102017
Ontogeny of the Major Xenobiotic‐Metabolizing Enzymes Expression and the Dietary Lipids Modulatory Effect in the Rat Dimethylbenz (a) anthracene‐Induced Breast Cancer Model
MA Manzanares, M Solanas, R Moral, R Escrich, E Vela, E Escrich
Journal of Biochemical and Molecular Toxicology 28 (12), 539-548, 2014
62014
SpliceCore (R) a platform for identifying aberrant alternative splicing in triple negative breast cancer for novel therapeutic development
MA Manzanares, D Priyanka, K Anderson, V Frederick, A Geier, A Casill, ...
MOLECULAR CANCER THERAPEUTICS 20 (12), 2021
12021
Development and validation of AI/ML derived splice-switching oligonucleotides
AD Fronk, MA Manzanares, P Zheng, A Geier, K Anderson, S Stanton, ...
Molecular Systems Biology, 1-26, 2024
2024
Novel splicing-derived neoantigen in triple negative breast cancer uncovered by SpliceIO™ a robust platform for the discovery and validation of disease-specific immunotherapies
N Williams, MA Manzanares, K Anderson, H Zunrut, S Gera, N Habib, ...
Cancer Research 84 (6_Supplement), 5894-5894, 2024
2024
Novel immune-therapeutic target for lung cancer uncovered by SpliceIO™, an innovative platform that identifies disease-specific alternative splicing
MA Manzanares, K Anderson, H Zumrut, S Gera, N Habib, N Williams, ...
Cancer Research 84 (6_Supplement), 5888-5888, 2024
2024
Calreticulin accelerates corneal wound closure and mitigates fibrosis: Potential therapeutic applications
S Mishra, MA Manzanares, J Prater, D Culp, LI Gold
Journal of Cellular and Molecular Medicine, 2024
2024
SpliceIO: A robust platform for the discovery and validation of splicing-derived neoantigens.
G Arun, K Anderson, MA Manzanares, S Gera, H Zumrut, S Smith, T Floyd, ...
Journal of Clinical Oncology 41 (16_suppl), 2581-2581, 2023
2023
Computational discovery and experimental validation of splicing-derived neoantigens
HE Zumrut, K Anderson, M Manzanares, S Smith, S Gera, N Habib, ...
Cancer Research 83 (7_Supplement), 448-448, 2023
2023
Development and validation of an AI/ML platform for the discovery of splice-switching oligonucleotide targets
AD Fronk, MA Manzanares, P Zheng, A Geier, K Anderson, V Frederick, ...
bioRxiv, 2022.10. 14.512313, 2022
2022
SpliceIO™ a novel AI platform for the discovery of splicing-derived immunotherapeutic targets
M Manzanares, H Zumrut, S Gera, A Casill, K Anderson, A Geier, ...
European Journal of Cancer 174, S126, 2022
2022
SpliceCore® a novel ML tool for identifying disease-specific alternative splicing uncovered a promising therapeutic target for triple negative breast cancer
MA Manzanares, A Casill, K Anderson, P Dhingra, V Frederick, A Geier, ...
Cancer Research 82 (12_Supplement), 1873-1873, 2022
2022
Abstract P5-17-11: Novel therapeutic target for triple negative breast cancer uncovered by SpliceCore® an innovative platform that identifies disease-specific alternative splicing
MA Manzanares, P Dhingra, K Anderson, V Frederick, A Geier, A Casill, ...
Cancer Research 82 (4_Supplement), P5-17-11-P5-17-11, 2022
2022
Novel therapeutic target for triple negative breast cancer uncovered by SpliceCore (R) an innovative platform that identifies disease-specific alternative splicing
MA Manzanares, P Dhingra, K Anderson, V Frederick, A Geier, A Casill, ...
CANCER RESEARCH 82 (4), 2022
2022
Abstract P170: SpliceCore® a platform for identifying aberrant alternative splicing in triple negative breast cancer for novel therapeutic development
MA Manzanares, D Priyanka, K Anderson, V Frederick, A Geier, A Casill, ...
Molecular Cancer Therapeutics 20 (12_Supplement), P170-P170, 2021
2021
Calreticulin exploits TGF-beta for extracellular matrix induction engineering a tissue regenerative process (vol 34, pg 15849, 2020)
UM Pandya, MA Manzanares, A Tellechea, C Egbuta, J Daubriac, ...
FASEB JOURNAL 35 (4), 2021
2021
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