Lipid nanoparticles for delivery of therapeutic RNA oligonucleotides KH Moss, P Popova, SR Hadrup, K Astakhova, M Taskova Molecular pharmaceutics 16 (6), 2265-2277, 2019 | 87 | 2019 |
Highly Fluorescent Conjugated Pyrenes in Nucleic Acid Probes:(Phenylethynyl) pyrenecarbonyl‐Functionalized Locked Nucleic Acids IV Astakhova, VA Korshun, J Wengel Chemistry–A European Journal 14 (35), 11010-11026, 2008 | 71 | 2008 |
Scaffolding along nucleic acid duplexes using 2′-amino-locked nucleic acids IK Astakhova, J Wengel Accounts of chemical research 47 (6), 1768-1777, 2014 | 70 | 2014 |
1‐, 2‐, and 4‐Ethynylpyrenes in the Structure of Twisted Intercalating Nucleic Acids: Structure, Thermal Stability, and Fluorescence Relationship VV Filichev, IV Astakhova, AD Malakhov, VA Korshun, EB Pedersen Chemistry–A European Journal 14 (32), 9968-9980, 2008 | 70 | 2008 |
Interfacing click chemistry with automated oligonucleotide synthesis for the preparation of fluorescent DNA probes containing internal xanthene and cyanine dyes IK Astakhova, J Wengel Chemistry–A European Journal 19 (3), 1112-1122, 2013 | 57 | 2013 |
Pyrene–perylene as a FRET pair coupled to the N2′-functionality of 2′-amino-LNA D Lindegaard, AS Madsen, IV Astakhova, AD Malakhov, BR Babu, ... Bioorganic & medicinal chemistry 16 (1), 94-99, 2008 | 57 | 2008 |
Perylene Attached to 2′-Amino-LNA: Synthesis, Incorporation into Oligonucleotides, and Remarkable Fluorescence Properties in Vitro and in Cell Culture IV Astakhova, VA Korshun, K Jahn, J Kjems, J Wengel Bioconjugate chemistry 19 (10), 1995-2007, 2008 | 55 | 2008 |
Sensitive SNP Dual‐Probe Assays Based on Pyrene‐Functionalized 2′‐Amino‐LNA: Lessons To Be Learned T Umemoto, PJ Hrdlicka, BR Babu, J Wengel ChemBioChem 8 (18), 2240-2248, 2007 | 47 | 2007 |
1-Phenylethynylpyrene (1-PEPy) as refined excimer forming alternative to pyrene: Case of DNA major groove excimer IV Astakhova, AD Malakhov, IA Stepanova, AV Ustinov, SL Bondarev, ... Bioconjugate chemistry 18 (6), 1972-1980, 2007 | 47 | 2007 |
Autoantibodies in morphea: an update S Khatri, KS Torok, E Mirizio, C Liu, K Astakhova Frontiers in immunology 10, 462707, 2019 | 40 | 2019 |
Antisense oligonucleotides internally labeled with peptides show improved target recognition and stability to enzymatic degradation M Taskova, CS Madsen, KJ Jensen, LH Hansen, B Vester, K Astakhova Bioconjugate chemistry 28 (3), 768-774, 2017 | 35 | 2017 |
Novel interstrand communication systems within DNA duplexes based on 1-, 2-and 4-(phenylethynyl) pyrenes attached to 2′-amino-LNA: high-affinity hybridization and fluorescence … IV Astakhova, D Lindegaard, VA Korshun, J Wengel Chemical communications 46 (44), 8362-8364, 2010 | 35 | 2010 |
Synthetic nucleic acid analogues in gene therapy: an update for peptide–oligonucleotide conjugates M Taskova, A Mantsiou, K Astakhova ChemBioChem 18 (17), 1671-1682, 2017 | 34 | 2017 |
Peptide–LNA oligonucleotide conjugates IK Astakhova, LH Hansen, B Vester, J Wengel Organic & Biomolecular Chemistry 11 (25), 4240-4249, 2013 | 34 | 2013 |
Branched DNA nanostructures efficiently stabilised and monitored by novel pyrene–perylene 2′-α-l-amino-LNA FRET pairs IK Astakhova, TS Kumar, MA Campbell, AV Ustinov, VA Korshun, ... Chemical communications 49 (5), 511-513, 2013 | 30 | 2013 |
Novel (phenylethynyl) pyrene–LNA constructs for fluorescence SNP sensing in polymorphic nucleic acid targets IK Astakhova, E Samokhina, BR Babu, J Wengel ChemBioChem 13 (10), 1509-1519, 2012 | 30 | 2012 |
Reactive trityl derivatives: stabilised carbocation mass-tags for life sciences applications AV Ustinov, VV Shmanai, K Patel, IA Stepanova, IA Prokhorenko, ... Organic & Biomolecular Chemistry 6 (24), 4593-4608, 2008 | 29 | 2008 |
Carbon nanotubes—potent carriers for targeted drug delivery in rheumatoid arthritis C Kofoed Andersen, S Khatri, J Hansen, S Slott, R Pavan Parvathaneni, ... Pharmaceutics 13 (4), 453, 2021 | 28 | 2021 |
LNA for optimization of fluorescent oligonucleotide probes: improved spectral properties and target binding IV Astakhova, AV Ustinov, VA Korshun, J Wengel Bioconjugate Chemistry 22 (4), 533-539, 2011 | 27 | 2011 |
Revealing nucleic acid mutations using Förster resonance energy transfer-based probes NPL Junager, J Kongsted, K Astakhova Sensors 16 (8), 1173, 2016 | 26 | 2016 |