| Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance T Matsuzaka, H Shimano, N Yahagi, T Kato, A Atsumi, T Yamamoto, ... Nature medicine 13 (10), 1193-1202, 2007 | 586 | 2007 |
| Role of NLRP3 inflammasomes in atherosclerosis T Karasawa, M Takahashi Journal of atherosclerosis and thrombosis 24 (5), 443-451, 2017 | 261 | 2017 |
| Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice F Usui, K Shirasuna, H Kimura, K Tatsumi, A Kawashima, T Karasawa, ... Biochemical and biophysical research communications 425 (2), 162-168, 2012 | 196 | 2012 |
| Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure N Yamada, T Karasawa, H Kimura, S Watanabe, T Komada, R Kamata, ... Cell death & disease 11 (2), 144, 2020 | 193 | 2020 |
| Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II–induced aortic aneurysm F Usui, K Shirasuna, H Kimura, K Tatsumi, A Kawashima, T Karasawa, ... Arteriosclerosis, thrombosis, and vascular biology 35 (1), 127-136, 2015 | 180 | 2015 |
| Iron overload as a risk factor for hepatic ischemia-reperfusion injury in liver transplantation: potential role of ferroptosis N Yamada, T Karasawa, T Wakiya, A Sadatomo, H Ito, R Kamata, ... American Journal of Transplantation 20 (6), 1606-1618, 2020 | 176 | 2020 |
| NLRP3 regulates neutrophil functions and contributes to hepatic ischemia–reperfusion injury independently of inflammasomes Y Inoue, K Shirasuna, H Kimura, F Usui, A Kawashima, T Karasawa, ... The Journal of Immunology 192 (9), 4342-4351, 2014 | 142 | 2014 |
| Saturated fatty acids undergo intracellular crystallization and activate the NLRP3 inflammasome in macrophages T Karasawa, A Kawashima, F Usui-Kawanishi, S Watanabe, H Kimura, ... Arteriosclerosis, thrombosis, and vascular biology 38 (4), 744-756, 2018 | 130 | 2018 |
| ARIH2 ubiquitinates NLRP3 and negatively regulates NLRP3 inflammasome activation in macrophages A Kawashima, T Karasawa, K Tago, H Kimura, R Kamata, ... The Journal of Immunology 199 (10), 3614-3622, 2017 | 118 | 2017 |
| Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells A Sampilvanjil, T Karasawa, N Yamada, T Komada, T Higashi, ... American Journal of Physiology-Heart and Circulatory Physiology 318 (3 …, 2020 | 114 | 2020 |
| Role of NLRP3 inflammasomes for rhabdomyolysis-induced acute kidney injury T Komada, F Usui, A Kawashima, H Kimura, T Karasawa, Y Inoue, ... Scientific reports 5 (1), 10901, 2015 | 108 | 2015 |
| ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction T Komada, F Usui, K Shirasuna, A Kawashima, H Kimura, T Karasawa, ... The American journal of pathology 184 (5), 1287-1298, 2014 | 82 | 2014 |
| Role of the NLRP3 inflammasome in preeclampsia K Shirasuna, T Karasawa, M Takahashi Frontiers in endocrinology 11, 503953, 2020 | 78 | 2020 |
| Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC K Shirasuna, F Usui, T Karasawa, H Kimura, A Kawashima, H Mizukami, ... Nanotoxicology 9 (5), 554-567, 2015 | 73 | 2015 |
| Palmitic acid induces interleukin-1β secretion via NLRP3 inflammasomes and inflammatory responses through ROS production in human placental cells K Shirasuna, H Takano, K Seno, A Ohtsu, T Karasawa, M Takahashi, ... Journal of reproductive immunology 116, 104-112, 2016 | 71 | 2016 |
| NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β Y Mizushina, K Shirasuna, F Usui, T Karasawa, A Kawashima, H Kimura, ... Journal of Biological Chemistry 290 (8), 5065-5077, 2015 | 71 | 2015 |
| NLRP3 deficiency improves angiotensin II-induced hypertension but not fetal growth restriction during pregnancy K Shirasuna, T Karasawa, F Usui, M Kobayashi, T Komada, H Kimura, ... Endocrinology 156 (11), 4281-4292, 2015 | 68 | 2015 |
| GSDME-dependent incomplete pyroptosis permits selective IL-1α release under caspase-1 inhibition E Aizawa, T Karasawa, S Watanabe, T Komada, H Kimura, R Kamata, ... Iscience 23 (5), 2020 | 64 | 2020 |
| NLRP3 deficiency reduces macrophage interleukin-10 production and enhances the susceptibility to doxorubicin-induced cardiotoxicity M Kobayashi, F Usui, T Karasawa, A Kawashima, H Kimura, Y Mizushina, ... Scientific reports 6 (1), 26489, 2016 | 64 | 2016 |
| Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes Y Nakagawa, A Satoh, S Yabe, M Furusawa, N Tokushige, H Tezuka, ... Endocrinology 155 (12), 4706-4719, 2014 | 60 | 2014 |
