WRN helicase is a synthetic lethal target in microsatellite unstable cancers EM Chan, T Shibue, JM McFarland, B Gaeta, M Ghandi, N Dumont, ... Nature 568 (7753), 551-556, 2019 | 282 | 2019 |
Synthetic lethal interaction of SHOC2 depletion with MEK inhibition in RAS-driven cancers R Sulahian, JJ Kwon, KH Walsh, E Pailler, TL Bosse, M Thaker, ... Cell reports 29 (1), 118-134. e8, 2019 | 71 | 2019 |
FOS licenses early events in stem cell activation driving skeletal muscle regeneration AE Almada, N Horwitz, FD Price, AE Gonzalez, M Ko, OV Bolukbasi, ... Cell Reports 34 (4), 108656, 2021 | 48 | 2021 |
Synthetic lethal interaction between the ESCRT paralog enzymes VPS4A and VPS4B in cancers harboring loss of chromosome 18q or 16q JE Neggers, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, A Yang, ... Cell reports 33 (11), 108493, 2020 | 30 | 2020 |
Phosphate dysregulation via the XPR1–KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer DP Bondeson, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, ... Nature Cancer, 1-15, 2022 | 27 | 2022 |
Selective modulation of a pan-essential protein as a therapeutic strategy in cancer CF Malone, NV Dharia, G Kugener, AB Forman, MV Rothberg, ... Cancer Discovery 11 (9), 2282-2299, 2021 | 25 | 2021 |
Drug screening at single-organoid resolution via bioprinting and interferometry PJ Tebon, B Wang, AL Markowitz, A Davarifar, BL Tsai, P Krawczuk, ... Nature Communications 14 (1), 3168, 2023 | 20 | 2023 |
A ubiquitination cascade regulating the integrated stress response and survival in carcinomas LD Cervia, T Shibue, AA Borah, B Gaeta, L He, L Leung, N Li, SM Moyer, ... Cancer discovery 13 (3), 766-795, 2023 | 12 | 2023 |
Prolonged FOS activity disrupts a global myogenic transcriptional program by altering 3D chromatin architecture in primary muscle progenitor cells AR Barutcu, G Elizalde, AE Gonzalez, K Soni, JL Rinn, AJ Wagers, ... Skeletal muscle 12 (1), 1-18, 2022 | 7 | 2022 |
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q JE Neggers, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, A Yang, ... Cell reports 36 (2), 2021 | 4 | 2021 |
Alteration of p‐PKM2 by UV radiation and H2O2 in Human Keratinocytes R Garrity, A Gonzalez, J Justiniano, Y Wan The FASEB Journal 29, 726.16, 2015 | 1 | 2015 |
Phosphate dysregulation as a novel therapeutic strategy in ovarian and uterine cancers D Bondeson, B Paolella, A Asfaw, M Rothberg, T Skipper, G Mesa, ... Cancer Research 82 (12_Supplement), 1028-1028, 2022 | | 2022 |
A ubiquitination cascade regulates the integrated stress response and epithelial cancer survival LD Cervia, T Shibue, B Gaeta, A Borah, L Leung, N Li, N Dumont, ... Cancer Research 81 (13 Supplement), 1950-1950, 2021 | | 2021 |
Abstract LB-053: VPS4A is a synthetic lethal target in VPS4B-deficient cancers due to co-deletion with SMAD4 JE Neggers, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, RL Kalekar, ... Cancer Research 80 (16 Supplement), LB-053-LB-053, 2020 | | 2020 |
Novel cell line barcoding method reveals tepoxalin as a selective drug against MDR1-high tumor cells SM Corsello, RD Spangler, RT Nagari, M Kocak, J Rossen, P O'Hearn, ... Cancer Research 79 (13 Supplement), 2948-2948, 2019 | | 2019 |
CRISPR-Cas9 screens identify the nuclear export factor NXT1 as a novel therapeutic target in MYCN-amplified neuroblastoma CF Malone, NV Dharia, G Kugener, B Paolella, M Rothberg, ... Cancer Research 79 (13 Supplement), 2878-2878, 2019 | | 2019 |
WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers A Bass, E Chan, T Shibue, J McFarland, B Gaeta, M Ghandi, N Dumont, ... Nature, 2018 | | 2018 |
Yeast Bax Inhibitor, BXI1, is involved in calcium homeostasis of the ER in Saccharomyces cerevisiae N Andrews, N Mello, L McDonough, J Alisch, D Eagan, J Mullin, ... Cancer Research 78 (13 Supplement), 308-308, 2018 | | 2018 |
Abstract 234A: Aberrant sodium current contributes to constitutive mTOR activity in malignant melanoma cells B Gallant, N Lizza, R Garrity, A Madigan, Z Jost, A Gonzalez, J Justiniano, ... Cancer Research 76 (14 Supplement), 234A-234A, 2016 | | 2016 |
mTOR and PKM2 are constitutively up-regulated in human melanoma cells but not in melanocytes A Gonzalez, J Justiniano, R Garrity, Y Cui, Y Wan JOURNAL OF INVESTIGATIVE DERMATOLOGY 135, S108-S108, 2015 | | 2015 |