| Local protease signaling contributes to neural tube closure in the mouse embryo E Camerer, A Barker, DN Duong, R Ganesan, H Kataoka, I Cornelissen, ... Developmental cell 18 (1), 25-38, 2010 | 179 | 2010 |
| Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression M Tripathi, S Nandana, H Yamashita, R Ganesan, D Kirchhofer, ... Journal of biological chemistry 283 (45), 30576-30584, 2008 | 116 | 2008 |
| Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2,-3,-6,-7,-8,-9, and-10 ÖD Ekici, ZZ Li, AJ Campbell, KE James, JL Asgian, J Mikolajczyk, ... Journal of medicinal chemistry 49 (19), 5728-5749, 2006 | 103 | 2006 |
| Structural and functional analysis of HtrA1 and its subdomains C Eigenbrot, M Ultsch, MT Lipari, P Moran, SJ Lin, R Ganesan, C Quan, ... Structure 20 (6), 1040-1050, 2012 | 102 | 2012 |
| Inhibiting alternative pathway complement activation by targeting the factor D exosite KJ Katschke, P Wu, R Ganesan, RF Kelley, MA Mathieu, PE Hass, ... Journal of Biological Chemistry 287 (16), 12886-12892, 2012 | 101 | 2012 |
| Structural insight into distinct mechanisms of protease inhibition by antibodies Y Wu, C Eigenbrot, WC Liang, S Stawicki, S Shia, B Fan, R Ganesan, ... Proceedings of the National Academy of Sciences 104 (50), 19784-19789, 2007 | 94 | 2007 |
| Regulatory T cell targeting in cancer: Emerging strategies in immunotherapy S Dees, R Ganesan, S Singh, IS Grewal European Journal of Immunology 51 (2), 280-291, 2021 | 88 | 2021 |
| Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies R Ganesan, EL Raymond, D Mennerich, JR Woska Jr, G Caviness, ... MAbs 9 (7), 1143-1154, 2017 | 78 | 2017 |
| Emerging CAR-T Cell Therapy for the Treatment of Triple Negative Breast Cancer ISG Sundee Dees, Rajkumar Ganesan, Sanjaya Singh Mol Cancer Ther ., 2020 | 74 | 2020 |
| Proteolytic activation of pro-macrophage-stimulating protein by hepsin R Ganesan, GA Kolumam, SJ Lin, MH Xie, L Santell, TD Wu, RA Lazarus, ... Molecular Cancer Research 9 (9), 1175-1186, 2011 | 73 | 2011 |
| Unraveling the allosteric mechanism of serine protease inhibition by an antibody R Ganesan, C Eigenbrot, Y Wu, WC Liang, S Shia, MT Lipari, ... Structure 17 (12), 1614-1624, 2009 | 66 | 2009 |
| Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis W Li, BE Wang, P Moran, T Lipari, R Ganesan, R Corpuz, MJC Ludlam, ... Cancer research 69 (21), 8395-8402, 2009 | 64 | 2009 |
| Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis R Ganesan, PRE Mittl, S Jelakovic, MG Grütter Journal of molecular biology 359 (5), 1378-1388, 2006 | 63 | 2006 |
| Structural and mechanistic insight into how antibodies inhibit serine proteases R Ganesan, C Eigenbrot, D Kirchhofer Biochemical Journal 430 (2), 179-189, 2010 | 56 | 2010 |
| Structural and functional attributes of the interleukin-36 receptor G Yi, JA Ybe, SS Saha, G Caviness, E Raymond, R Ganesan, ML Mbow, ... Journal of Biological Chemistry 291 (32), 16597-16609, 2016 | 54 | 2016 |
| The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyperproliferative epidermis of psoriasis and regenerating wounds W Li, DM Danilenko, S Bunting, R Ganesan, S Sa, R Ferrando, TD Wu, ... Journal of biological chemistry 284 (1), 218-228, 2009 | 52 | 2009 |
| Human caspases in vitro: expression, purification and kinetic characterization H Roschitzki-Voser, T Schroeder, ED Lenherr, F Frölich, A Schweizer, ... Protein expression and purification 84 (2), 236-246, 2012 | 45 | 2012 |
| Selective recruitment of γδ T cells by a bispecific antibody for the treatment of acute myeloid leukemia SSISG Rajkumar Ganesan, Vijaykumar Chennupati, Balaji Ramachandran, Michael ... Leukemia, 2021 | 39 | 2021 |
| Design and characterization of Zweimab and Doppelmab, high affinity dual antagonistic anti-TSLP/IL13 bispecific antibodies S Venkataramani, S Low, B Weigle, D Dutcher, K Jerath, M Menzenski, ... Biochemical and biophysical research communications 504 (1), 19-24, 2018 | 38 | 2018 |
| Bispecific antibodies for triple negative breast cancer S Dees, R Ganesan, S Singh, IS Grewal Trends in cancer 7 (2), 162-173, 2021 | 37 | 2021 |
