| 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice AD Rathnayake, J Zheng, Y Kim, KD Perera, S Mackin, DK Meyerholz, ... Science translational medicine 12 (557), eabc5332, 2020 | 228 | 2020 |
| The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase YMO Alhammad, MM Kashipathy, A Roy, JP Gagné, P McDonald, P Gao, ... Journal of virology 95 (3), 10.1128/jvi. 01969-20, 2021 | 99 | 2021 |
| Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection CS Dampalla, J Zheng, KD Perera, LYR Wong, DK Meyerholz, ... Proceedings of the National Academy of Sciences 118 (29), e2101555118, 2021 | 75 | 2021 |
| Structure-guided design of conformationally constrained cyclohexane inhibitors of severe acute respiratory syndrome coronavirus-2 3CL protease CS Dampalla, Y Kim, N Bickmeier, AD Rathnayake, HN Nguyen, J Zheng, ... Journal of medicinal chemistry 64 (14), 10047-10058, 2021 | 49 | 2021 |
| Structure-guided design of potent inhibitors of SARS-CoV-2 3CL protease: structural, biochemical, and cell-based studies CS Dampalla, AD Rathnayake, KD Perera, ARM Jesri, HN Nguyen, ... Journal of medicinal chemistry 64 (24), 17846-17865, 2021 | 34 | 2021 |
| Structure-guided design of potent spirocyclic inhibitors of severe acute respiratory syndrome coronavirus-2 3C-like protease CS Dampalla, AD Rathnayake, AC Galasiti Kankanamalage, Y Kim, ... Journal of Medicinal Chemistry 65 (11), 7818-7832, 2022 | 24 | 2022 |
| The SARS-CoV-2 conserved macrodomain is a highly efficient ADP-ribosylhydrolase YMO Alhammad, MM Kashipathy, A Roy, JP Gagne, L Nonfoux, ... BioRxiv, 2020 | 19 | 2020 |
| Structure-guided optimization of dipeptidyl inhibitors of norovirus 3CL protease AD Rathnayake, Y Kim, CS Dampalla, HN Nguyen, ARM Jesri, ... Journal of Medicinal Chemistry 63 (20), 11945-11963, 2020 | 15 | 2020 |
| Costameric integrin and sarcoglycan protein levels are altered in a Drosophila model for Limb-girdle muscular dystrophy type 2H S Bawa, S Gameros, K Baumann, DS Brooks, JA Kollhoff, M Zolkiewski, ... Molecular Biology of the Cell 32 (3), 260-273, 2021 | 13 | 2021 |
| Structure of the diphtheria toxin at acidic pH: Implications for the conformational switching of the translocation domain MV Rodnin, MM Kashipathy, A Kyrychenko, KP Battaile, S Lovell, ... Toxins 12 (11), 704, 2020 | 11 | 2020 |
| Broad-spectrum cyclopropane-based inhibitors of coronavirus 3C-like proteases: biochemical, structural, and virological studies CS Dampalla, HN Nguyen, AD Rathnayake, Y Kim, KD Perera, ... ACS Pharmacology & Translational Science 6 (1), 181-194, 2022 | 9 | 2022 |
| Crystal and solution structures of human oncoprotein Musashi‐2 N‐terminal RNA recognition motif 1 L Lan, M Xing, M Kashipathy, J Douglas, P Gao, K Battaile, R Hanzlik, ... Proteins: Structure, Function, and Bioinformatics 88 (4), 573-583, 2020 | 9 | 2020 |
| Structural insight into the novel iron‐coordination and domain interactions of transferrin‐1 from a model insect, Manduca sexta JJ Weber, MM Kashipathy, KP Battaile, E Go, H Desaire, MR Kanost, ... Protein Science 30 (2), 408-422, 2021 | 8 | 2021 |
| Crystal structure of VapBC-1 from nontypeable Haemophilus influenzae and the effect of pin domain mutations on survival during infection AL Molinaro, MM Kashipathy, S Lovell, KP Battaile, NP Coussens, ... Journal of Bacteriology 201 (12), 10.1128/jb. 00026-19, 2019 | 8 | 2019 |
| 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med 12: eabc5332 AD Rathnayake, J Zheng, Y Kim, KD Perera, S Mackin, DK Meyerholz, ... | 7 | 2020 |
| 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med. 2020; 12 (557) AD Rathnayake, J Zheng, Y Kim, KD Perera, S Mackin, DK Meyerholz, ... Epub 2020/08/05. doi: 10.1126/scitranslmed. abc5332. PubMed PMID: 32747425, 0 | 6 | |
| RNA structures and dynamics with Å resolution revealed by x-ray free-electron lasers KA Zielinski, S Sui, SA Pabit, DA Rivera, T Wang, Q Hu, MM Kashipathy, ... Science Advances 9 (39), eadj3509, 2023 | 5 | 2023 |
| Structure–activity relationship of ipglycermide binding to phosphoglycerate mutases M Wiedmann, PK Dranchak, M Aitha, B Queme, CD Collmus, ... Journal of Biological Chemistry 296, 2021 | 3 | 2021 |
| Pseudomonas aeruginosa Dps (PA0962) Functions in H2O2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity N Rajapaksha, A Soldano, H Yao, F Donnarumma, MM Kashipathy, ... International Journal of Molecular Sciences 24 (5), 4669, 2023 | 2 | 2023 |
| Histidine Protonation and Conformational Switching in Diphtheria Toxin Translocation Domain MV Rodnin, V Vasques-Montes, A Kyrychenko, NFB Oliveira, ... Toxins 15 (7), 410, 2023 | 1 | 2023 |
