Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer M Lacroix, R Riscal, G Arena, LK Linares, L Le Cam Molecular metabolism 33, 2-22, 2020 | 274 | 2020 |
Even cancer cells watch their cholesterol! R Riscal, N Skuli, MC Simon Molecular cell 76 (2), 220-231, 2019 | 159 | 2019 |
FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome F Li, P Huangyang, M Burrows, K Guo, R Riscal, J Godfrey, KE Lee, N Lin, ... Nature cell biology 22 (6), 728-739, 2020 | 129 | 2020 |
Chromatin-bound MDM2 regulates serine metabolism and redox homeostasis independently of p53 R Riscal, E Schrepfer, G Arena, MY Cissé, F Bellvert, M Heuillet, ... Molecular cell 62 (6), 890-902, 2016 | 114 | 2016 |
Mitochondrial MDM2 regulates respiratory complex I activity independently of p53 G Arena, MY Cissé, S Pyrdziak, L Chatre, R Riscal, M Fuentes, JJ Arnold, ... Molecular cell 69 (4), 594-609. e8, 2018 | 88 | 2018 |
Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia H Boutzen, E Saland, C Larrue, F De Toni, L Gales, FA Castelli, ... Journal of Experimental Medicine 213 (4), 483-497, 2016 | 85 | 2016 |
Cholesterol auxotrophy as a targetable vulnerability in clear cell renal cell carcinoma R Riscal, CJ Bull, C Mesaros, JM Finan, M Carens, ES Ho, JP Xu, ... Cancer discovery 11 (12), 3106-3125, 2021 | 54 | 2021 |
GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment R Missiaen, NM Anderson, LC Kim, B Nance, M Burrows, N Skuli, ... Cell metabolism 34 (8), 1151-1167. e7, 2022 | 50 | 2022 |
Gamma-glutamyltransferase 1 promotes clear cell renal cell carcinoma initiation and progression A Bansal, DJ Sanchez, V Nimgaonkar, D Sanchez, R Riscal, N Skuli, ... Molecular Cancer Research 17 (9), 1881-1892, 2019 | 38 | 2019 |
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma MY Cissé, S Pyrdziak, N Firmin, L Gayte, M Heuillet, F Bellvert, M Fuentes, ... Science translational medicine 12 (547), eaay2163, 2020 | 34 | 2020 |
Glycogen metabolism is dispensable for tumour progression in clear cell renal cell carcinoma H Xie, J Song, J Godfrey, R Riscal, N Skuli, I Nissim, MC Simon Nature metabolism 3 (3), 327-336, 2021 | 26 | 2021 |
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis P Goguet-Rubio, B Seyran, L Gayte, F Bernex, A Sutter, H Delpech, ... Proceedings of the National Academy of Sciences 113 (39), 11004-11009, 2016 | 25 | 2016 |
MDM2 controls gene expression independently of p53 in both normal and cancer cells G Arena, R Riscal, LK Linares, L Le Cam Cell death and differentiation 25 (9), 1533, 2018 | 19 | 2018 |
Chromatin-bound MDM2, a new player in metabolism R Riscal, L Le Cam, LK Linares Molecular & Cellular Oncology 3 (5), e1210560, 2016 | 4 | 2016 |
Glucagon signaling via supraphysiologic GCGR can reduce cell viability without stimulating gluconeogenic gene expression in liver cancer cells J Godfrey, R Riscal, N Skuli, MC Simon Cancer & Metabolism 10 (1), 4, 2022 | 3 | 2022 |
Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma R Riscal, SM Gardner, NJ Coffey, M Carens, C Mesaros, JP Xu, Y Xue, ... Cancer Research, 2024 | | 2024 |
Give and Take: The Reciprocal Control of Metabolism and Cell Cycle R Riscal, B Riquier-Morcant, G Gadea, LK Linares Cell Cycle Control: Methods and Protocols, 155-168, 2024 | | 2024 |
Isolating human RCC tumor cells details evolutionary relationships between cancer cell subsets and a role of OXPHOS in disease progression R Riscal, S Gardner, M Carens, C Mesaros, J Xu, N Coffey, L Davis, ... CANCER RESEARCH 83 (16), 2023 | | 2023 |
Abstract B008: Activation of the bile acid pathway promotes tumorigenesis in clear cell renal cell carcinoma R Riscal, S Gardner, M Carens, C Mesaros, J Xu, N Coffey, L Davis, ... Cancer Research 83 (16_Supplement), B008-B008, 2023 | | 2023 |
Abstract B003: Increasing branched-chain amino acid metabolism reduces clear cell renal cell carcinoma growth NJ Coffey, R Riscal, N Skuli, NP Lesner, M Noji, C Jiang, LC Kim, X Han, ... Cancer Research 83 (16_Supplement), B003-B003, 2023 | | 2023 |