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Romain Riscal
Romain Riscal
Verified email at pennmedicine.upenn.edu
Title
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Cited by
Year
Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer
M Lacroix, R Riscal, G Arena, LK Linares, L Le Cam
Molecular metabolism 33, 2-22, 2020
2742020
Even cancer cells watch their cholesterol!
R Riscal, N Skuli, MC Simon
Molecular cell 76 (2), 220-231, 2019
1592019
FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome
F Li, P Huangyang, M Burrows, K Guo, R Riscal, J Godfrey, KE Lee, N Lin, ...
Nature cell biology 22 (6), 728-739, 2020
1292020
Chromatin-bound MDM2 regulates serine metabolism and redox homeostasis independently of p53
R Riscal, E Schrepfer, G Arena, MY Cissé, F Bellvert, M Heuillet, ...
Molecular cell 62 (6), 890-902, 2016
1142016
Mitochondrial MDM2 regulates respiratory complex I activity independently of p53
G Arena, MY Cissé, S Pyrdziak, L Chatre, R Riscal, M Fuentes, JJ Arnold, ...
Molecular cell 69 (4), 594-609. e8, 2018
882018
Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia
H Boutzen, E Saland, C Larrue, F De Toni, L Gales, FA Castelli, ...
Journal of Experimental Medicine 213 (4), 483-497, 2016
852016
Cholesterol auxotrophy as a targetable vulnerability in clear cell renal cell carcinoma
R Riscal, CJ Bull, C Mesaros, JM Finan, M Carens, ES Ho, JP Xu, ...
Cancer discovery 11 (12), 3106-3125, 2021
542021
GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
R Missiaen, NM Anderson, LC Kim, B Nance, M Burrows, N Skuli, ...
Cell metabolism 34 (8), 1151-1167. e7, 2022
502022
Gamma-glutamyltransferase 1 promotes clear cell renal cell carcinoma initiation and progression
A Bansal, DJ Sanchez, V Nimgaonkar, D Sanchez, R Riscal, N Skuli, ...
Molecular Cancer Research 17 (9), 1881-1892, 2019
382019
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma
MY Cissé, S Pyrdziak, N Firmin, L Gayte, M Heuillet, F Bellvert, M Fuentes, ...
Science translational medicine 12 (547), eaay2163, 2020
342020
Glycogen metabolism is dispensable for tumour progression in clear cell renal cell carcinoma
H Xie, J Song, J Godfrey, R Riscal, N Skuli, I Nissim, MC Simon
Nature metabolism 3 (3), 327-336, 2021
262021
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis
P Goguet-Rubio, B Seyran, L Gayte, F Bernex, A Sutter, H Delpech, ...
Proceedings of the National Academy of Sciences 113 (39), 11004-11009, 2016
252016
MDM2 controls gene expression independently of p53 in both normal and cancer cells
G Arena, R Riscal, LK Linares, L Le Cam
Cell death and differentiation 25 (9), 1533, 2018
192018
Chromatin-bound MDM2, a new player in metabolism
R Riscal, L Le Cam, LK Linares
Molecular & Cellular Oncology 3 (5), e1210560, 2016
42016
Glucagon signaling via supraphysiologic GCGR can reduce cell viability without stimulating gluconeogenic gene expression in liver cancer cells
J Godfrey, R Riscal, N Skuli, MC Simon
Cancer & Metabolism 10 (1), 4, 2022
32022
Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma
R Riscal, SM Gardner, NJ Coffey, M Carens, C Mesaros, JP Xu, Y Xue, ...
Cancer Research, 2024
2024
Give and Take: The Reciprocal Control of Metabolism and Cell Cycle
R Riscal, B Riquier-Morcant, G Gadea, LK Linares
Cell Cycle Control: Methods and Protocols, 155-168, 2024
2024
Isolating human RCC tumor cells details evolutionary relationships between cancer cell subsets and a role of OXPHOS in disease progression
R Riscal, S Gardner, M Carens, C Mesaros, J Xu, N Coffey, L Davis, ...
CANCER RESEARCH 83 (16), 2023
2023
Abstract B008: Activation of the bile acid pathway promotes tumorigenesis in clear cell renal cell carcinoma
R Riscal, S Gardner, M Carens, C Mesaros, J Xu, N Coffey, L Davis, ...
Cancer Research 83 (16_Supplement), B008-B008, 2023
2023
Abstract B003: Increasing branched-chain amino acid metabolism reduces clear cell renal cell carcinoma growth
NJ Coffey, R Riscal, N Skuli, NP Lesner, M Noji, C Jiang, LC Kim, X Han, ...
Cancer Research 83 (16_Supplement), B003-B003, 2023
2023
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