A series of novel, highly potent, and orally bioavailable next-generation tricyclic peptide PCSK9 inhibitors TJ Tucker, MW Embrey, C Alleyne, RP Amin, A Bass, B Bhatt, E Bianchi, ... Journal of Medicinal Chemistry 64 (22), 16770-16800, 2021 | 70 | 2021 |
A proximal bisnitroxide initiator: studies in low-temperature nitroxide-mediated polymerizations J Ruehl, NL Hill, ED Walter, G Millhauser, R Braslau Macromolecules 41 (6), 1972-1982, 2008 | 40 | 2008 |
Synthesis and characterization of a novel bisnitroxide initiator for effecting “outside-in” polymerization NL Hill, R Braslau Macromolecules 38 (22), 9066-9074, 2005 | 38 | 2005 |
Discovery of MK-8831, a novel spiro-proline macrocycle as a pan-genotypic HCV-NS3/4a protease inhibitor SF Neelamkavil, S Agrawal, T Bara, C Bennett, S Bhat, D Biswas, ... ACS Medicinal Chemistry Letters 7 (1), 111-116, 2016 | 31 | 2016 |
Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys SB Hoyt, MK Park, C London, Y Xiong, J Tata, DJ Bennett, A Cooke, J Cai, ... ACS medicinal chemistry letters 6 (5), 573-578, 2015 | 26 | 2015 |
Synthesis of thiol-derivatized initiators for nitroxide-mediated radical polymerization: Reversible disulfide formation NL Hill, JL Jarvis, F Pettersson, R Braslau Reactive and Functional Polymers 68 (1), 361-368, 2008 | 24 | 2008 |
Synthesis of arylethyl-functionalized N-alkoxyamine initiators and use in nitroxide-mediated radical polymerization NL Hill, R Braslau Journal of Polymer Science-A-Polymer Chemistry Edition 45 (11), 2341, 2007 | 21 | 2007 |
Discovery of triazole CYP11B2 inhibitors with in vivo activity in rhesus monkeys SB Hoyt, W Petrilli, C London, GB Liang, J Tata, Q Hu, L Yin, ... ACS Medicinal Chemistry Letters 6 (8), 861-865, 2015 | 17 | 2015 |
Discovery and optimization of a novel triazole series of GPR142 agonists for the treatment of type 2 diabetes L Guo, DL Parker, Y Zang, RF Sweis, W Liu, EC Sherer, N Buist, ... ACS medicinal chemistry letters 7 (12), 1107-1111, 2016 | 15 | 2016 |
Assessing the Utility of In Vitro Screening Tools for Predicting Bio-Performance of Oral Peptide Delivery P Gadgil, C Alleyne, KI Feng, M Hu, M Gindy, AV Buevich, S Fauty, ... Pharmaceutical Research 36, 1-15, 2019 | 13 | 2019 |
Preclinical Characterization of the Phosphodiesterase 10A PET Tracer [11C]MK-8193 ED Hostetler, H Fan, AD Joshi, Z Zeng, W Eng, L Gantert, M Holahan, ... Molecular imaging and biology 18, 579-587, 2016 | 9 | 2016 |
Impacting Global Health Through Equipment Repurposing: Measurable Progress Through the Accumulation of Many Tiny Victories NL Buist, EC Minnihan, K Young, L Yang Journal of Pharmaceutical Sciences 107 (3), 788-793, 2018 | | 2018 |
Discovery of selective CYP11B2 inhibitors as potential treatments for resistant hypertension S Hoyt, W Petrilli, M Park, J Taylor, C London, A Cooke, J Cai, E Carswell, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
Discovery of triazole aldosterone synthase inhibitors with in vivo activity in Rhesus monkeys S Hoyt, W Petrilli, C London, J Tata, Q Hu, L Yin, C van Koppen, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |
Development of novel functionalized bis-nitroxide initiators for the preparation of designed polymers NL Hill University of California, Santa Cruz, 2007 | | 2007 |
POLY 40-Low temperature nitroxide-mediated polymerization by a bis-N-alkoxyamine initiator NL Hill, R Braslau ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 232, 2006 | | 2006 |