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Hooman Hefzi
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Recon 2.2: from reconstruction to model of human metabolism
N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ...
Metabolomics 12, 1-7, 2016
3072016
Sensory maps in the olfactory cortex defined by long-range viral tracing of single neurons
S Ghosh, SD Larson, H Hefzi, Z Marnoy, T Cutforth, K Dokka, KK Baldwin
Nature 472 (7342), 217-220, 2011
2952011
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
Cell systems 3 (5), 434-443. e8, 2016
2352016
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion
JM Gutierrez, A Feizi, S Li, TB Kallehauge, H Hefzi, LM Grav, D Ley, ...
Nature communications 11 (1), 68, 2020
982020
Quantitative feature extraction from the Chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow
A Golabgir, JM Gutierrez, H Hefzi, S Li, BO Palsson, C Herwig, NE Lewis
Biotechnology advances 34 (5), 621-633, 2016
512016
Systematic evaluation of site-specific recombinant gene expression for programmable mammalian cell engineering
N Pristovsek, S Nallapareddy, LM Grav, H Hefzi, NE Lewis, P Rugbjerg, ...
ACS synthetic biology 8 (4), 758-774, 2019
452019
Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow
E Brunk, RL Chang, J Xia, H Hefzi, JT Yurkovich, D Kim, E Buckmiller, ...
Proceedings of the National Academy of Sciences 115 (43), 11096-11101, 2018
422018
Awakening dormant glycosyltransferases in CHO cells with CRISPRa
KJC Karottki, H Hefzi, K Xiong, I Shamie, AH Hansen, S Li, LE Pedersen, ...
Biotechnology and bioengineering 117 (2), 593-598, 2020
332020
Functional interrogation of Plasmodium genus metabolism identifies species-and stage-specific differences in nutrient essentiality and drug targeting
AM Abdel-Haleem, H Hefzi, K Mineta, X Gao, T Gojobori, BO Palsson, ...
PLoS computational biology 14 (1), e1005895, 2018
332018
Reprogramming AA catabolism in CHO cells with CRISPR/Cas9 genome editing improves cell growth and reduces byproduct secretion
D Ley, S Pereira, LE Pedersen, J Arnsdorf, H Hefzi, AM Davy, TK Ha, ...
Metabolic engineering 56, 120-129, 2019
292019
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
KJ la Cour Karottki, H Hefzi, S Li, LE Pedersen, PN Spahn, C Joshi, ...
Metabolic engineering 66, 114-122, 2021
192021
An optimized genome-wide, virus-free CRISPR screen for mammalian cells
K Xiong, KJ la Cour Karottki, H Hefzi, S Li, LM Grav, S Li, P Spahn, JS Lee, ...
Cell Reports Methods 1 (4), 2021
182021
Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells
PN Spahn, X Zhang, Q Hu, H Lu, NK Hamaker, H Hefzi, S Li, CC Kuo, ...
Biotechnology and bioengineering 119 (3), 963-982, 2022
172022
WormJam: A consensus C. elegans Metabolic Reconstruction and Metabolomics Community and Workshop Series
J Hastings, A Mains, M Artal-Sanz, S Bergmann, BP Braeckman, J Bundy, ...
Worm 6 (2), e1373939, 2017
172017
From random mutagenesis to systems biology in metabolic engineering of mammalian cells
H Hefzi, NE Lewis
Pharmaceutical Bioprocessing 2 (5), 355-358, 2014
142014
A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells
I Shamie, SH Duttke, KJC Karottki, CZ Han, AH Hansen, H Hefzi, K Xiong, ...
NAR genomics and bioinformatics 3 (3), lqab061, 2021
102021
A Consensus genomescale reconstruction of Chinese hamster ovary cell metabolism. Cell Syst 3 (5): 434-443. e8
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
62016
Recon 2.2: from reconstruction to model of human metabolism. Metabolomics 12
N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ...
62016
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism. Cell Syst. 3, 434–443 e8
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
52016
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium
TK Ha, A ̉dena, KJC Karottki, CL Kim, H Hefzi, GM Lee, ...
Biotechnology and Bioengineering 120 (4), 1159-1166, 2023
42023
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