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Deepthi Ashok
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High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria
GW Rogers, MD Brand, S Petrosyan, D Ashok, AA Elorza, DA Ferrick, ...
PloS one 6 (7), e21746, 2011
4902011
Clinical utility of random anti–tumor necrosis factor drug–level testing and measurement of antidrug antibodies on the long‐term treatment response in rheumatoid arthritis
M Jani, H Chinoy, RB Warren, CEM Griffiths, D Plant, B Fu, AW Morgan, ...
Arthritis & rheumatology 67 (8), 2011-2019, 2015
1102015
Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening
AL Orr, D Ashok, MR Sarantos, T Shi, RE Hughes, MD Brand
Free Radical Biology and Medicine 65, 1047-1059, 2013
842013
Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase
AL Orr, D Ashok, MR Sarantos, R Ng, T Shi, AA Gerencser, RE Hughes, ...
PLoS One 9 (2), e89938, 2014
572014
A new phenotype of brain iron accumulation with dystonia, optic atrophy, and peripheral neuropathy
R Horvath, E Holinski‐Feder, VCM Neeve, A Pyle, H Griffin, D Ashok, ...
Movement disorders 27 (6), 789-793, 2012
562012
Mitochondrial Ca2+ in heart failure: Not enough or too much?
B O'Rourke, D Ashok, T Liu
Journal of molecular and cellular cardiology 151, 126-134, 2021
342021
Global knockout of ROMK potassium channel worsens cardiac ischemia-reperfusion injury but cardiomyocyte-specific knockout does not: Implications for the identity of mitoKATP
KN Papanicolaou, D Ashok, T Liu, TM Bauer, J Sun, Z Li, E Da Costa, ...
Journal of molecular and cellular cardiology 139, 176-189, 2020
312020
Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old
J Collerton, D Ashok, C Martin-Ruiz, A Pyle, G Hudson, M Yadegarfar, ...
Neurobiology of aging 34 (12), 2889. e1-2889. e4, 2013
212013
Inhibition of phosphodiesterase type 9 reduces obesity and cardiometabolic syndrome in mice
S Mishra, N Sadagopan, B Dunkerly-Eyring, S Rodriguez, DC Sarver, ...
The Journal of Clinical Investigation 131 (21), 2021
18*2021
Reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old
L Wiley, D Ashok, C Martin-Ruiz, DCS Talbot, J Collerton, A Kingston, ...
PLoS One 9 (3), e91005, 2014
152014
Nuclear-mitochondrial communication involving miR-181c plays an important role in cardiac dysfunction during obesity
B Roman, P Kaur, D Ashok, M Kohr, R Biswas, B O'Rourke, ...
Journal of molecular and cellular cardiology 144, 87-96, 2020
132020
Mitochondrial membrane potential instability on reperfusion after ischemia does not depend on mitochondrial Ca2+ uptake
D Ashok, K Papanicolaou, A Sidor, M Wang, S Solhjoo, T Liu, B O’Rourke
Journal of Biological Chemistry 299 (6), 2023
92023
Inhibiting O-GlcNAcylation impacts p38 and Erk1/2 signaling and perturbs cardiomyocyte hypertrophy
KN Papanicolaou, J Jung, D Ashok, W Zhang, A Modaressanavi, E Avila, ...
Journal of Biological Chemistry 299 (3), 2023
82023
MitoWave: Spatiotemporal analysis of mitochondrial membrane potential fluctuations during I/R
D Ashok, B O’Rourke
Biophysical journal 120 (16), 3261-3271, 2021
52021
Reverse-mode Mitochondrial Na+ / Ca2+ Mitochondrial Exchange, Not the Mcu, is the Primary Mode of Ca2+ Import Into the Mitochondria During Ischemia …
D Ashok, K Papanicolaou, T Liu, B O'Rourke
Circulation Research 127 (Suppl_1), A554-A554, 2020
12020
Reverse-mode mitochondrial Na+/Ca2+ exchange, not the MCU, is the primary mode of Ca2+ import into the mitochondria during ischemia/reperfusion in neonatal cardiac myocytes
D Ashok, K Papanicolaou, T Liu, B O'Rourke
Biophysical Journal 118 (3), 407a, 2020
12020
Enhancing mitochondrial biogenesis with a CRISPR/ndCas9 adenoviral vector system in cardiomyocytes
D Ashok, A Sidor, B O'Rourke
Biophysical Journal 114 (3), 662a, 2018
12018
Regulation of stress granules by O-GlcNAcylation in stressed and ischemic cardiomyocytes
HC Swimm, W Zhang, Y Mallikarjun, D Ashok, DB Foster, B O'Rourke, ...
Biophysical Journal 123 (3), 218a-219a, 2024
2024
Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19
D Ashok, T Liu, J Criscione, M Prakash, B Kim, J Chow, M Craney, ...
bioRxiv, 2024.01. 05.574280, 2024
2024
Role of O-GlcNAcylation in stress granule formation in cardiomyocytes undergoing chemical or ischemic challenges
H Swimm, W Zhang, Y Mallikarjun, D Ashok, DB Foster, B O'Rourke, ...
GLYCOBIOLOGY 33 (11), 977-978, 2023
2023
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