| Imaging dopamine receptors in humans with [11C]-(+)-PHNO: dissection of D3 signal and anatomy AC Tziortzi, GE Searle, S Tzimopoulou, C Salinas, JD Beaver, ... Neuroimage 54 (1), 264-277, 2011 | 448 | 2011 |
| Connectivity-based functional analysis of dopamine release in the striatum using diffusion-weighted MRI and positron emission tomography AC Tziortzi, SN Haber, GE Searle, C Tsoumpas, CJ Long, P Shotbolt, ... Cerebral cortex 24 (5), 1165-1177, 2014 | 341 | 2014 |
| Imaging dopamine D3 receptors in the human brain with positron emission tomography,[11C] PHNO, and a selective D3 receptor antagonist G Searle, JD Beaver, RA Comley, M Bani, A Tziortzi, M Slifstein, ... Biological psychiatry 68 (4), 392-399, 2010 | 169 | 2010 |
| Within-Subject Comparison of [11C]-( + )-PHNO and [11C]raclopride Sensitivity to Acute Amphetamine Challenge in Healthy Humans P Shotbolt, AC Tziortzi, GE Searle, A Colasanti, J Van Der Aart, ... Journal of Cerebral Blood Flow & Metabolism 32 (1), 127-136, 2012 | 144 | 2012 |
| Endogenous opioid release in the human brain reward system induced by acute amphetamine administration A Colasanti, GE Searle, CJ Long, SP Hill, RR Reiley, D Quelch, D Erritzoe, ... Biological psychiatry 72 (5), 371-377, 2012 | 130 | 2012 |
| Positron emission tomography imaging of amphetamine‐induced dopamine release in the human cortex: A comparative evaluation of the high affinity dopamine D2/3 radiotracers [11C … R Narendran, WG Frankle, NS Mason, EA Rabiner, RN Gunn, GE Searle, ... Synapse 63 (6), 447-461, 2009 | 129 | 2009 |
| Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson’s disease F Niccolini, T Foltynie, T Reis Marques, N Muhlert, AC Tziortzi, GE Searle, ... Brain 138 (10), 3003-3015, 2015 | 123 | 2015 |
| The simplified reference tissue model: model assumption violations and their impact on binding potential CA Salinas, GE Searle, RN Gunn Journal of Cerebral Blood Flow & Metabolism 35 (2), 304-311, 2015 | 120 | 2015 |
| Altered PDE10A expression detectable early before symptomatic onset in Huntington’s disease F Niccolini, S Haider, T Reis Marques, N Muhlert, AC Tziortzi, GE Searle, ... Brain 138 (10), 3016-3029, 2015 | 118 | 2015 |
| Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target occupancy and food reward-related brain activation in humans EA Rabiner, J Beaver, A Makwana, G Searle, C Long, PJ Nathan, ... Molecular psychiatry 16 (8), 826-835, 2011 | 117 | 2011 |
| A Multi-Center Randomized Proof-of-Concept Clinical Trial Applying [18F]FDG-PET for Evaluation of Metabolic Therapy with Rosiglitazone XR in Mild to Moderate … S Tzimopoulou, VJ Cunningham, TE Nichols, G Searle, NP Bird, P Mistry, ... Journal of Alzheimer’s Disease 22 (4), 1241-1256, 2011 | 111 | 2011 |
| Neuroinflammation and its relationship to changes in brain volume and white matter lesions in multiple sclerosis G Datta, A Colasanti, EA Rabiner, RN Gunn, O Malik, O Ciccarelli, ... Brain 140 (11), 2927-2938, 2017 | 98 | 2017 |
| Kinetic analysis of the translocator protein positron emission tomography ligand [18F]GE-180 in the human brain C Feeney, G Scott, J Raffel, S Roberts, C Coello, A Jolly, G Searle, ... European journal of nuclear medicine and molecular imaging 43, 2201-2210, 2016 | 89 | 2016 |
| Quantitative imaging of protein targets in the human brain with PET RN Gunn, M Slifstein, GE Searle, JC Price Physics in Medicine & Biology 60 (22), R363, 2015 | 87 | 2015 |
| Blunted endogenous opioid release following an oral amphetamine challenge in pathological gamblers I Mick, J Myers, AC Ramos, PRA Stokes, D Erritzoe, A Colasanti, ... Neuropsychopharmacology 41 (7), 1742-1750, 2016 | 81 | 2016 |
| Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer A Saleem, GE Searle, LM Kenny, M Huiban, K Kozlowski, AD Waldman, ... EJNMMI research 5, 1-10, 2015 | 76 | 2015 |
| Orbitofrontal connectivity with resting-state networks is associated with midbrain dopamine D3 receptor availability DM Cole, CF Beckmann, GE Searle, C Plisson, AC Tziortzi, TE Nichols, ... Cerebral Cortex 22 (12), 2784-2793, 2012 | 76 | 2012 |
| Combining PET biodistribution and equilibrium dialysis assays to assess the free brain concentration and BBB transport of CNS drugs RN Gunn, SG Summerfield, CA Salinas, KD Read, Q Guo, GE Searle, ... Journal of Cerebral Blood Flow & Metabolism 32 (5), 874-883, 2012 | 74 | 2012 |
| Application of a generic physiologically based pharmacokinetic model to the estimation of xenobiotic levels in human plasma FA Brightman, DE Leahy, GE Searle, S Thomas Drug metabolism and disposition 34 (1), 94-101, 2006 | 73 | 2006 |
| Guidelines for the content and format of PET brain data in publications and archives: a consensus paper GM Knudsen, M Ganz, S Appelhoff, R Boellaard, G Bormans, RE Carson, ... Journal of Cerebral Blood Flow & Metabolism 40 (8), 1576-1585, 2020 | 69 | 2020 |
