| Discovery of small molecules that target the Phosphatidylinositol (3, 4, 5) Trisphosphate (PIP3)-Dependent Rac Exchanger 1 (P-Rex1) PIP3-Binding Site and Inhibit P-Rex1 … JN Cash, NR Chandan, AY Hsu, PV Sharma, Q Deng, AV Smrcka, ... Molecular pharmacology 97 (3), 226-236, 2020 | 13 | 2020 |
| A network of Gαi signaling partners is revealed by proximity labeling proteomics analysis and includes PDZ-RhoGEF NR Chandan, S Abraham, S SenGupta, CA Parent, AV Smrcka Science signaling 15 (717), eabi9869, 2022 | 8 | 2022 |
| Signaling, Physiology, and Targeting of GPCR‐Regulated Phospholipase C Enzymes NR Chandan, AV Smrcka, HTN Phan GPCRs as Therapeutic Targets 1, 458-520, 2022 | 2 | 2022 |
| Identification of G Protein αi Signaling Partners by Proximity Labeling Reveals a Network of Interactions that Includes PDZ-RhoGEF NR Chandan, S Abraham, S SenGupta, CA Parent, AV Smrcka bioRxiv, 2021.07. 15.452545, 2021 | 2 | 2021 |
| Stabilization of interdomain interactions in G protein α subunits as a determinant of Gαi subtype signaling specificity TJ Lefevre, W Wei, E Mukhaleva, SPM Venkata, NR Chandan, S Abraham, ... Journal of Biological Chemistry 300 (5), 2024 | 1 | 2024 |
| Identification of a sequence of the activity-dependent neuroprotective protein (ADNP) that is necessary for its interaction with G?? i1 N Momplaisir, NR Chandan, AV Smrcka Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
| SMARCD3: A Link Between Gαq and Chromatin Remodeling? J Loomis, NR Chandan, AV Smrcka Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
| Identification of the Activity‐Dependent Neuroprotective Protein (ADNP) as a Novel Effector of Gαi1 NL Momplaisir, N Chandan, T Lefevre, AV Smrcka The FASEB Journal 36, 2022 | | 2022 |
| Identifying Novel Signaling Mechanisms Downstream of Gq‐Coupled Receptors JF Loomis, NR Chandan, MJ Brody, AV Smrcka The FASEB Journal 36, 2022 | | 2022 |
| Identification of PDZ‐RhoGEF (PRG) as a Novel Gαi Target N Chandan, S Abraham, S SenGupta, C Parent, A Smrcka The FASEB Journal 35, 2021 | | 2021 |
| Signaling Specificity of the Gαi G Protein Subfamily8.5.5 T Lefevre, N Chandan, A Smrcka The FASEB Journal 35, 2021 | | 2021 |
| Identification and Characterization of G Protein Signaling Networks by Proximity Labeling-Coupled Proteomics NR Chandan | | 2021 |
| Identification of PDZ‐RhoGEF as a Novel Target of Gαi Signaling NR Chandan, A Saji, AV Smrcka The FASEB Journal 34, 1-1, 2020 | | 2020 |
| Discovery of small molecules that target the P-Rex1 PIP3-binding site and inhibit P-Rex1-dependent functions in neutrophils JN Cash, NR Chandan, AY Hsu, PV Sharma, Q Deng, AV Smrcka, ... Molecular Pharmacology, 2020 | | 2020 |
Alan SmrckaProfessor of Pharmacology, University of MichiganVerified email at umich.edu
