| Neutrophil-derived proteases escalate inflammation through activation of IL-36 family cytokines CM Henry, GP Sullivan, DM Clancy, IS Afonina, D Kulms, SJ Martin Cell reports 14 (4), 708-722, 2016 | 323 | 2016 |
| Extracellular neutrophil proteases are efficient regulators of IL-1, IL-33, and IL-36 cytokine activity but poor effectors of microbial killing DM Clancy, GP Sullivan, HBT Moran, CM Henry, EP Reeves, ... Cell reports 22 (11), 2937-2950, 2018 | 184 | 2018 |
| Neutrophil extracellular traps can serve as platforms for processing and activation of IL‐1 family cytokines DM Clancy, CM Henry, GP Sullivan, SJ Martin The FEBS journal 284 (11), 1712-1725, 2017 | 114 | 2017 |
| iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE I Oikonomidi, E Burbridge, M Cavadas, G Sullivan, B Collis, H Naegele, ... Elife 7, e35032, 2018 | 62 | 2018 |
| TRAIL receptors serve as stress-associated molecular patterns to promote ER-stress-induced inflammation GP Sullivan, H O’Connor, CM Henry, P Davidovich, DM Clancy, ML Albert, ... Developmental Cell 52 (6), 714-730. e5, 2020 | 50 | 2020 |
| Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases GP Sullivan, CM Henry, DM Clancy, T Mametnabiev, E Belotcerkovskaya, ... Cell death & disease 9 (3), 378, 2018 | 47 | 2018 |
| Identification of small‐molecule elastase inhibitors as antagonists of IL‐36 cytokine activation GP Sullivan, PB Davidovich, S Sura‐Trueba, E Belotcerkovskaya, ... FEBS open bio 8 (5), 751-763, 2018 | 21 | 2018 |
| Production of biologically active IL‐36 family cytokines through insertion of N‐terminal caspase cleavage motifs DM Clancy, CM Henry, PB Davidovich, GP Sullivan, E Belotcerkovskaya, ... FEBS Open Bio 6 (4), 338-348, 2016 | 18 | 2016 |
| The path to venetoclax resistance is paved with mutations, metabolism, and more GP Sullivan, L Flanagan, DA Rodrigues, T Ní Chonghaile Science Translational Medicine 14 (674), eabo6891, 2022 | 11 | 2022 |
| Myeloid cell–derived proteases produce a proinflammatory form of IL-37 that signals via IL-36 receptor engagement GP Sullivan, P Davidovich, N Muñoz-Wolf, RW Ward, ... Science Immunology 7 (78), eade5728, 2022 | 5 | 2022 |
| Extracellular neutrophil proteases are efficient regulators of IL-1, IL-33, and IL-36 cytokine activity but poor effectors of microbial killing. Cell Rep 2018; 22: 2937-50 DM Clancy, GP Sullivan, HBT Moran, CM Henry, EP Reeves, ... | 5 | 2018 |
| IL-1α and IL-36 family cytokines can undergo processing and activation by diverse allergen-associated proteases V Frezza, Z Najda, P Davidovich, GP Sullivan, SJ Martin Frontiers in Immunology 13, 879029, 2022 | 4 | 2022 |
| Use of inhibitors of il-36 proteolytic processing for the treatment and/or reduction of inflammation SJ Martin, C Henry, G Sullivan US Patent App. 15/512,139, 2017 | 2 | 2017 |
| First-in-class metallo-PROTAC as an effective degrader of select Pt-binding proteins PD O’Dowd, GP Sullivan, DA Rodrigues, TN Chonghaile, DM Griffith Chemical Communications 59 (84), 12641-12644, 2023 | 1 | 2023 |
| Method for treatment of inflammatory skin disorders with inhibitors of IL-36 proteolytic processing SJ Martin, C Henry, G Sullivan US Patent 10,744,179, 2020 | | 2020 |
| Inflammatory Outcomes of Diverse Forms of Homeostatic Perturbation G Sullivan Trinity College Dublin, 2018 | | 2018 |
| Use of inhibitors of il-36 proteolytic processing for the treatment and/or reduction of inflammation SJ Martin, C Henry, G Sullivan | | 2016 |
