| An enhanced CRISPR repressor for targeted mammalian gene regulation NC Yeo, A Chavez, A Lance-Byrne, Y Chan, D Menn, D Milanova, ... Nature methods 15 (8), 611-616, 2018 | 423 | 2018 |
| Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions JP Shen, D Zhao, R Sasik, J Luebeck, A Birmingham, ... Nature methods 14 (6), 573-576, 2017 | 359 | 2017 |
| The emerging role of systems biology for engineering protein production in CHO cells CC Kuo, AWT Chiang, I Shamie, M Samoudi, JM Gutierrez, NE Lewis Current Opinion in Biotechnology 51, 64-69, 2018 | 104 | 2018 |
| Increasing consensus of context-specific metabolic models by integrating data-inferred cell functions A Richelle, AWT Chiang, CC Kuo, NE Lewis PLoS computational biology 15 (4), e1006867, 2019 | 71 | 2019 |
| Modulating carbohydrate–protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology AWT Chiang, S Li, PN Spahn, A Richelle, CC Kuo, M Samoudi, NE Lewis Current opinion in structural biology 40, 104-111, 2016 | 28 | 2016 |
| Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins M Malm, CC Kuo, MM Barzadd, A Mebrahtu, N Wistbacka, R Razavi, ... Metabolic engineering 72, 171-187, 2022 | 19 | 2022 |
| Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells PN Spahn, X Zhang, Q Hu, H Lu, NK Hamaker, H Hefzi, S Li, CC Kuo, ... Biotechnology and bioengineering 119 (3), 963-982, 2022 | 17 | 2022 |
| A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis LY Hsieh, AWT Chiang, LD Duong, CC Kuo, SX Dong, R Dohil, R Kurten, ... Journal of Allergy and Clinical Immunology 148 (2), 486-494, 2021 | 16 | 2021 |
| Combating viral contaminants in CHO cells by engineering innate immunity AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ... Scientific reports 9 (1), 8827, 2019 | 16 | 2019 |
| The human secretome–the proteins secreted from human cells M Uhlen, H Tegel, Å Sivertsson, CC Kuo, JM Gutierrez, NE Lewis, ... BioRxiv, 465815, 2018 | 16 | 2018 |
| Dysregulation of the secretory pathway connects Alzheimer’s disease genetics to aggregate formation CC Kuo, AWT Chiang, HM Baghdassarian, NE Lewis Cell systems 12 (9), 873-884. e4, 2021 | 14 | 2021 |
| Increased mAb production in amplified CHO cell lines is associated with increased interaction of CREB1 with transgene promoter H Dahodwala, P Kaushik, V Tejwani, CC Kuo, P Menard, M Henry, ... Current research in biotechnology 1, 49-57, 2019 | 14 | 2019 |
| Systems glycobiology for discovering drug targets, biomarkers, and rational designs for glyco-immunotherapy AWT Chiang, HM Baghdassarian, BP Kellman, B Bao, JT Sorrentino, ... Journal of Biomedical Science 28, 1-15, 2021 | 7 | 2021 |
| From omics to cellular mechanisms in mammalian cell factory development M Samoudi, HO Masson, CC Kuo, CM Robinson, NE Lewis Current opinion in chemical engineering 32, 100688, 2021 | 6 | 2021 |
| In situ detection of protein interactions for recombinant therapeutic enzymes M Samoudi, CC Kuo, CM Robinson, K Shams‐Ud‐Doha, SM Schinn, ... Biotechnology and bioengineering 118 (2), 890-904, 2021 | 4 | 2021 |
| Combating viral contaminants in CHO cells by engineering STAT1 mediated innate immunity AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ... bioRxiv, 423590, 2018 | 3 | 2018 |
| Deciphering the determinants of recombinant protein yield across the human secretome HO Masson, CC Kuo, M Malm, M Lundqvist, Å Sievertsson, A Berling, ... bioRxiv, 2022.12. 12.520152, 2022 | 2 | 2022 |
| Inferring secretory and metabolic pathway activity from omic data with secCellFie HO Masson, M Samoudi, CM Robinson, CC Kuo, L Weiss, KSU Doha, ... Metabolic Engineering 81, 273-285, 2024 | 1 | 2024 |
| Restoration of deficient DNA Repair Genes Mitigates Genome Instability and Increases Productivity of Chinese Hamster Ovary Cells PN Spahn, X Zhang, Q Hu, NK Hamaker, H Hefzi, S Li, CC Kuo, Y Huang, ... bioRxiv, 2021.01. 07.425558, 2021 | 1 | 2021 |
| A Novel Tissue-Free Method to Estimate Tumor-Derived Cell-Free DNA Quantity Using Tumor Methylation Patterns CA Melton, P Freese, Y Zhou, A Shenoy, S Bagaria, C Chang, CC Kuo, ... Cancers 16 (1), 82, 2023 | | 2023 |
