| On the selectivity of heparan sulfate recognition by SARS-CoV-2 spike glycoprotein JE Chittum, NV Sankaranarayanan, CP O’Hara, UR Desai ACS Medicinal Chemistry Letters 12 (11), 1710-1717, 2021 | 28 | 2021 |
| Glycan Modulation of Insulin‐like Growth Factor‐1 Receptor RS Boothello, NV Sankaranarayanan, JC Sistla, B Nagarajan, C Sharon, ... Angewandte Chemie 134 (49), e202211320, 2022 | 7 | 2022 |
| Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting In Vivo Anticancer Activity S Morla, O Ravikumar, C O’Hara, R Boothello, A Vera, EI Abdelfadiel, ... Journal of Medicinal Chemistry 66 (2), 1321-1338, 2023 | 3 | 2023 |
| Mechanistic Studies on Glycosaminoglycan Mimetics Binding to Cancer Related Proteins CP O'Hara | | 2023 |
| Non-Saccharide Glycosaminoglycan Mimetics Selectively Target Certain Receptor Tyrosine Kinases to Induce Anti-Cancer Stem Cell Activity C O’Hara, S Morla, RK Ongolu, NV Sankaranarayanan, N Patel, ... Journal of Biological Chemistry 299 (3), S141, 2023 | | 2023 |
| Synthetic, small molecule glycosaminoglycan mimetics induce novel anti-cancer activity through preferential targeting of a growth factor receptor C O'Hara, S Morla, R Ongolu, N Patel, R Boothello, B Patel, U Desai Cancer Research 82 (12_Supplement), 2653-2653, 2022 | | 2022 |
| Lipidic analogs of anti-cancer stem cell agent UR Desai, B Nagarajan, OH Connor, DK Afosah, EI Abdelfadiel, J Sistla, ... US Patent App. 17/436,448, 2022 | | 2022 |
| Synthetic mimetics of Glycosaminoglycans preferentially target insulin-like growth Factor-1 receptor present on surface of colorectal spheroids C O'Hara, S Morla, R Ongolu, N Patel, R Boothello, B Patel, U Desai GLYCOBIOLOGY 31 (12), 1687-1687, 2021 | | 2021 |
| Structurally defined glycosaminoglycan mimetics exhibit preference for proteins of the growth factor family CP O'Hara, NV Sankaranarayanan, RS Boothello, BB Patel, UR Desai Cancer Research 81 (13_Supplement), 1166-1166, 2021 | | 2021 |
| Heparan Sulfate Microarray Lends Insight into Selective Binding of SARS‐CoV‐2 Spike Glycoprotein J Chittum, N Sankaranarayanan, C O'Hara, U Desai The FASEB Journal 35, 2021 | | 2021 |
| Identification of the pharmacophore defining SARS-CoV-2 spike glycoprotein-Heparan Sulfate interaction based on microarray and computational studies J Chittum, NV Sankaranarayanan, C O'Hara, U Desai Glycobiology, 1699-1699, 2021 | | 2021 |
| Cholesterol modification enhances potency and pharmacokinetic properties of a selective cancer stem cell targeting agent CP O'Hara, RS Boothello, S Morla, A Vera, DK Afosah, ... Cancer Research 80 (16_Supplement), 6353-6353, 2020 | | 2020 |
| Selective Inhibition of a Panel of Cancer Stem Cell Lines by Novel Glycosaminoglycan Mimetics CP O'Hara, S Morla, D Afosah, C Sharon, R Boothello, B Patel, U Desai The FASEB Journal 33 (S1), 675.11-675.11, 2019 | | 2019 |
| Lipophilic Modification of an Anti‐Cancer Stem Cell Agent Improves Pharmacokinetic and Anti‐Cancer Properties S Morla, DK Afosah, C O'Hara, R Boothello, BB Patel, M Sakagami, ... The FASEB Journal 33 (S1), 782.17-782.17, 2019 | | 2019 |
| Inhibition of Cancer Stem Cells by Glycosaminoglycan Mimetics CP O'Hara | | 2019 |
Umesh DesaiProfessor of Medicinal Chemistry, Virginia Commonwealth UniversityVerified email at vcu.edu
