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Neil Mody
Neil Mody
MedImmune/ AstraZeneca
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Computational tool for the early screening of monoclonal antibodies for their viscosities
NJ Agrawal, B Helk, S Kumar, N Mody, HA Sathish, HS Samra, PM Buck, ...
MAbs 8 (1), 43-48, 2016
912016
Developability assessment of engineered monoclonal antibody variants with a complex self-association behavior using complementary analytical and in silico tools
L Shan, N Mody, P Sormani, KL Rosenthal, MM Damschroder, ...
Molecular pharmaceutics 15 (12), 5697-5710, 2018
562018
An “Fc-silenced” IgG1 format with extended half-life designed for improved stability
MJ Borrok, N Mody, X Lu, ML Kuhn, H Wu, WF Dall'Acqua, P Tsui
Journal of Pharmaceutical Sciences 106 (4), 1008-1017, 2017
482017
Utility of high throughput screening techniques to predict stability of monoclonal antibody formulations during early stage development
DS Goldberg, RA Lewus, R Esfandiary, DC Farkas, N Mody, KJ Day, ...
Journal of Pharmaceutical Sciences 106 (8), 1971-1977, 2017
452017
Machine learning prediction of antibody aggregation and viscosity for high concentration formulation development of protein therapeutics
PK Lai, A Gallegos, N Mody, HA Sathish, BL Trout
MAbs 14 (1), 2026208, 2022
322022
Understanding the role of preferential exclusion of sugars and polyols from native state IgG1 monoclonal antibodies and its effect on aggregation and reversible self-association
CM Sudrik, T Cloutier, N Mody, HA Sathish, BL Trout
Pharmaceutical Research 36, 1-12, 2019
282019
Molecular computations of preferential interaction coefficients of IgG1 monoclonal antibodies with sorbitol, sucrose, and trehalose and the impact of these excipients on …
T Cloutier, C Sudrik, N Mody, HA Sathish, BL Trout
Molecular pharmaceutics 16 (8), 3657-3664, 2019
232019
Machine learning models of antibody–excipient preferential interactions for use in computational formulation design
TK Cloutier, C Sudrik, N Mody, HA Sathish, BL Trout
Molecular Pharmaceutics 17 (9), 3589-3599, 2020
192020
Molecular computations of preferential interactions of proline, arginine. HCl, and NaCl with IgG1 antibodies and their impact on aggregation and viscosity
TK Cloutier, C Sudrik, N Mody, SA Hasige, BL Trout
MAbs 12 (1), 1816312, 2020
182020
Highland games: A benchmarking exercise in predicting biophysical and drug properties of monoclonal antibodies from amino acid sequences
J Coffman, B Marques, R Orozco, M Aswath, H Mohammad, ...
Biotechnology and Bioengineering 117 (7), 2100-2115, 2020
102020
Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies
A Dippel, A Gallegos, V Aleti, A Barnes, X Chen, E Christian, J Delmar, ...
Mabs 15 (1), 2152526, 2023
52023
Computational tool for the early screening of monoclonal antibodies for their viscosities. MAbs 8, 43–48
NJ Agrawal, B Helk, S Kumar, N Mody, HA Sathish, HS Samra, BL Trout
52016
Antibody formulations
MN Dimitrova, N Mody
US Patent 8,754,195, 2014
52014
Identification of a new IgG mAb format with enhanced complement mediated effector function and extended half life
A Digiandomenico, A Dippel, R Varkey, A Lidwell, L Zhuang, V Godfrey, ...
C65. COPD: PRE-CLINICAL MODELS AND MECHANISMS, A4648-A4648, 2022
12022
Critical reagents for ligand-binding assays: process development methodologies to enable high-quality reagents
C Kittinger, J Delmar, L Hewitt, R Holcomb, C Jones, H Jones, R Kubiak, ...
Bioanalysis 14 (3), 117-135, 2021
12021
Antibody formulations
MN Dimitrova, N Mody
12014
Antibody formulations
MN Dimitrova, N Mody
12012
Minimizing self-association: Application of conformational and colloidal stability analyses in developing an optimal formulation
N Mody, HS Samra, NJ DeJesus, SM Bishop, MN Dimitrova
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 241, 2011
2011
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Articles 1–18