Follow
Gopinath Prakasam
Gopinath Prakasam
Verified email at utsouthwestern.edu
Title
Cited by
Cited by
Year
MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance
MA Iqbal, S Arora, G Prakasam, GA Calin, MA Syed
Molecular aspects of medicine 70, 3-20, 2019
3732019
Pyruvate kinase M2 and cancer: an updated assessment
MA Iqbal, V Gupta, P Gopinath, S Mazurek, RNK Bamezai
FEBS letters 588 (16), 2685-2692, 2014
2302014
Posttranslational modifications of pyruvate kinase M2: tweaks that benefit cancer
G Prakasam, MA Iqbal, RNK Bamezai, S Mazurek
Frontiers in oncology 8, 22, 2018
1342018
Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition
FA Siddiqui, G Prakasam, S Chattopadhyay, AU Rehman, RA Padder, ...
Scientific reports 8 (1), 8323, 2018
1282018
Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2
MA Iqbal, FA Siddiqui, V Gupta, S Chattopadhyay, P Gopinath, B Kumar, ...
Molecular cancer 12, 1-12, 2013
1052013
DNA Methyltransferase1 (DNMT1) Isoform3 methylates mitochondrial genome and modulates its biology
SK Saini, KC Mangalhara, G Prakasam, RNK Bamezai
Scientific reports 7 (1), 1525, 2017
812017
Pyruvate kinase M knockdown–induced signaling via AMP-activated protein kinase promotes mitochondrial biogenesis, autophagy, and cancer cell survival
G Prakasam, RK Singh, MA Iqbal, SK Saini, AB Tiku, RNK Bamezai
Journal of Biological Chemistry 292 (37), 15561-15576, 2017
612017
Silibinin induces metabolic crisis in triple‐negative breast cancer cells by modulating EGFR‐MYC‐TXNIP axis: potential therapeutic implications
MA Iqbal, S Chattopadhyay, FA Siddiqui, A Ur Rehman, S Siddiqui, ...
The FEBS journal 288 (2), 471-485, 2021
432021
Missense mutations in pyruvate kinase M2 promote cancer metabolism, oxidative endurance, anchorage independence, and tumor growth in a dominant negative manner
MA Iqbal, FA Siddiqui, N Chaman, V Gupta, B Kumar, P Gopinath, ...
Journal of Biological Chemistry 289 (12), 8098-8105, 2014
272014
Role of ectopically expressed mtDNA encoded cytochrome c oxidase subunit I (MT-COI) in tumorigenesis
RK Singh, SK Saini, G Prakasam, P Kalairasan, RNK Bamezai
Mitochondrion 49, 56-65, 2019
202019
Interplay between epigenetics & cancer metabolism
V Gupta, P Gopinath, M Askandar Iqbal, S Mazurek, K E Wellen, ...
Current pharmaceutical design 20 (11), 1706-1714, 2014
182014
ERK2-pyruvate kinase axis permits phorbol 12-myristate 13-acetate-induced megakaryocyte differentiation in K562 cells
N Chaman, MA Iqbal, FA Siddiqui, P Gopinath, RNK Bamezai
Journal of Biological Chemistry 290 (39), 23803-23815, 2015
172015
Pyruvate kinase
G Prakasam, RNK Bamezai
Academic Press, 2019
72019
Heterotypic signaling of cancer-associated fibroblasts in shaping the cancer cell drug resistance
R Butti, A Khaladkar, P Bhardwaj, G Prakasam
Cancer Drug Resistance 6 (1), 182, 2023
62023
HPV18 oncoproteins driven expression of PKM2 reprograms HeLa cell metabolism to maintain aerobic glycolysis and viability
G Prakasam, MA Iqbal, A Srivastava, RNK Bamezai, RK Singh
Virusdisease 33 (3), 223-235, 2022
22022
Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis
G Prakasam, A Mishra, A Christie, J Miyata, D Carrillo, VT Tcheuyap, H Ye, ...
The Journal of Clinical Investigation, 2024
12024
Abstract PR004: Comparative genomic analysis of novel translocation renal cell carcinoma model reveals molecular mechanisms of disease progression and therapeutic opportunities
G Prakasam, A Mishra, A Christie, J Miyata, VT Tcheuyap, H Ye, QN Do, ...
Cancer Research 83 (16_Supplement), PR004-PR004, 2023
2023
AMP-Activated Protein Kinase (AMPK)
G Prakasam, MA Iqbal, RK Singh, RNK Bamezai
Encyclopedia of Signaling Molecules, 301-312, 2018
2018
Abstract B19: LKB1-AMPK axis regulates the switch of Pyruvate Kinase M isoforms to tolerate nutritional stress
G Prakasam, RNK Bamezai
Molecular Cancer Research 14 (1_Supplement), B19-B19, 2016
2016
IoT-Driven Roof Support Management in Underground Mining: Enhancing Safety and Efficiency
D Haripranesh, L Arulmurugan, P Gopinath, B Kumar
The system can't perform the operation now. Try again later.
Articles 1–20