Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin P Krafcikova, J Silhan, R Nencka, E Boura Nature communications 11 (1), 3717, 2020 | 257 | 2020 |
Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein DC Dinesh, D Chalupska, J Silhan, E Koutna, R Nencka, V Veverka, ... PLoS Pathogens 16 (12), e1009100, 2020 | 243 | 2020 |
14-3-3 proteins: a family of versatile molecular regulators V Obšlova, J Šilhan, E BouŔa, J Teisinger, T Obšil Physiol Res, S11-S21, 2008 | 186 | 2008 |
Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair MRG Hodskinson, J Silhan, GP Crossan, JI Garaycoechea, S Mukherjee, ... Molecular cell 54 (3), 472-484, 2014 | 161 | 2014 |
Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding E Boura, J Silhan, P Herman, J Vecer, M Sulc, J Teisinger, V Obsilova, ... Journal of biological chemistry 282 (11), 8265-8275, 2007 | 98 | 2007 |
Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms KJPPK Michael R. Hodskinson, Alice Bolner, Koichi Sato, Ashley N. Kamimae ... Nature, 2020 | 96 | 2020 |
14-3-3 protein C-terminal stretch occupies ligand binding groove and is displaced by phosphopeptide binding J Silhan, V Obsilova, J Vecer, P Herman, M Sulc, J Teisinger, T Obsil Journal of Biological Chemistry 279 (47), 49113-49119, 2004 | 86 | 2004 |
14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4 J Silhan, P Vacha, P Strnadova, J Vecer, P Herman, M Sulc, J Teisinger, ... Journal of biological chemistry 284 (29), 19349-19360, 2009 | 79 | 2009 |
The 14-3-3 protein affects the conformation of the regulatory domain of human tyrosine hydroxylase V Obsilova, E Nedbalkova, J Silhan, E Boura, P Herman, J Vecer, M Sulc, ... Biochemistry 47 (6), 1768-1777, 2008 | 71 | 2008 |
Kobuviral Non-structural 3A Proteins Act as Molecular Harnesses to Hijack the Host ACBD3 Protein EB Martin Klima, Dominika Chalupska, Bartosz Różycki, Jana Humpolickova ... Structure 25 (February 7), 1-12, 2017 | 43* | 2017 |
Coronaviral RNA-methyltransferases: function, structure and inhibition R Nencka, J Silhan, M Klima, T Otava, H Kocek, P Krafcikova, E Boura Nucleic acids research 50 (2), 635-650, 2022 | 40 | 2022 |
A network of enzymes involved in repair of oxidative DNA damage in Neisseria meningitidis K Nagorska, J Silhan, Y Li, V Pelicic, PS Freemont, GS Baldwin, CM Tang Molecular microbiology 83 (5), 1064-1079, 2012 | 26 | 2012 |
Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis D Lu, J Silhan, JT MacDonald, EP Carpenter, K Jensen, CM Tang, ... Proceedings of the National Academy of Sciences 109 (42), 16852-16857, 2012 | 25 | 2012 |
The interactions of the C-terminal region of the TRPC6 channel with calmodulin E Friedlova, L Grycova, B Holakovska, J Silhan, H Janouskova, M Sulc, ... Neurochemistry international 56 (2), 363-366, 2010 | 24 | 2010 |
Specialization of an Exonuclease III family enzyme in the repair of 3′ DNA lesions during base excision repair in the human pathogen Neisseria meningitidis J Silhan, K Nagorska, Q Zhao, K Jensen, PS Freemont, CM Tang, ... Nucleic acids research 40 (5), 2065-2075, 2012 | 16 | 2012 |
Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase EB Jan Silhan, Martin Klima,Tomas Otava, Petr Skvara, Dominika Chalupska ... Nature Communications 14, 1-9, 2023 | 14* | 2023 |
Conformational Changes of DNA Repair Glycosylase MutM Triggered by DNA Binding JS Barbora Landova FEBS Lett., 2020 | 14 | 2020 |
High-throughput fluorescent assay for inhibitor screening of proteases from RNA viruses B Cihlova, A Huskova, J Böserle, R Nencka, E Boura, J Silhan Molecules 26 (13), 3792, 2021 | 13 | 2021 |
Structural analysis of the OC43 coronavirus 2′-O-RNA methyltransferase P Dostalik, P Krafcikova, J Silhan, J Kozic, D Chalupska, K Chalupsky, ... Journal of virology 95 (15), 10.1128/jvi. 00463-21, 2021 | 12 | 2021 |
The rate of formation and stability of abasic site interstrand crosslinks in the DNA duplex A Huskova, B Landova, E Boura, J Silhan DNA repair 113, 103300, 2022 | 7 | 2022 |