Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2–/– mice and human cholangiocarcinoma tumorigenesis L Kennedy, L Hargrove, J Demieville, W Karstens, H Jones, S DeMorrow, ... Hepatology 68 (3), 1042-1056, 2018 | 64 | 2018 |
The interplay between mast cells, pineal gland, and circadian rhythm: Links between histamine, melatonin, and inflammatory mediators L Pham, L Baiocchi, L Kennedy, K Sato, V Meadows, F Meng, CK Huang, ... Journal of pineal research 70 (2), e12699, 2021 | 55 | 2021 |
Mast cells induce ductular reaction mimicking liver injury in mice through mast cell–derived transforming growth factor beta 1 signaling K Kyritsi, L Kennedy, V Meadows, L Hargrove, J Demieville, L Pham, ... Hepatology 73 (6), 2397-2410, 2021 | 41* | 2021 |
Mast cells regulate ductular reaction and intestinal inflammation in cholestasis through farnesoid X receptor signaling V Meadows, L Kennedy, B Ekser, K Kyritsi, D Kundu, T Zhou, L Chen, ... Hepatology 74 (5), 2684-2698, 2021 | 40 | 2021 |
Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC M Awoniyi, J Wang, B Ngo, V Meadows, J Tam, A Viswanathan, Y Lai, ... Gut 72 (4), 671-685, 2023 | 39 | 2023 |
Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2−/− mouse model of primary sclerosing cholangitis (PSC) T Zhou, K Kyritsi, N Wu, H Francis, Z Yang, L Chen, A O'Brien, L Kennedy, ... EBioMedicine 48, 130-142, 2019 | 38 | 2019 |
Mast cells promote nonalcoholic fatty liver disease phenotypes and microvesicular steatosis in mice fed a western diet L Kennedy, V Meadows, A Sybenga, J Demieville, L Chen, L Hargrove, ... Hepatology 74 (1), 164-182, 2021 | 37 | 2021 |
Bile acid receptor therapeutics effects on chronic liver diseases V Meadows, L Kennedy, D Kundu, G Alpini, H Francis Frontiers in Medicine 7, 15, 2020 | 31 | 2020 |
Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2−/− mice V Meadows, L Kennedy, L Hargrove, J Demieville, F Meng, S Virani, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (12), 165557, 2019 | 31 | 2019 |
Inhibition of secretin/secretin receptor axis ameliorates NAFLD phenotypes L Chen, N Wu, L Kennedy, H Francis, L Ceci, T Zhou, N Samala, K Kyritsi, ... Hepatology 74 (4), 1845-1863, 2021 | 26 | 2021 |
Biliary damage and liver fibrosis are ameliorated in a novel mouse model lacking l-histidine decarboxylase/histamine signaling L Kennedy, V Meadows, J Demieville, L Hargrove, S Virani, S Glaser, ... Laboratory Investigation 100 (6), 837-848, 2020 | 24 | 2020 |
Functional role of the secretin/secretin receptor signaling during cholestatic liver injury N Wu, L Baiocchi, T Zhou, L Kennedy, L Ceci, F Meng, K Sato, C Wu, ... Hepatology 72 (6), 2219-2227, 2020 | 23 | 2020 |
Secretin alleviates biliary and liver injury during late-stage primary biliary cholangitis via restoration of secretory processes L Kennedy, G Carpino, T Owen, L Ceci, D Kundu, V Meadows, K Kyritsi, ... Journal of Hepatology 78 (1), 99-113, 2023 | 20 | 2023 |
Feedback signaling between cholangiopathies, ductular reaction, and non-alcoholic fatty liver disease T Zhou, D Kundu, J Robles-Linares, V Meadows, K Sato, L Baiocchi, ... Cells 10 (8), 2072, 2021 | 18 | 2021 |
Biliary epithelial senescence in liver disease: there will be SASP V Meadows, L Baiocchi, D Kundu, K Sato, Y Fuentes, C Wu, ... Frontiers in Molecular Biosciences 8, 803098, 2021 | 17 | 2021 |
Amelioration of large bile duct damage by histamine-2 receptor vivo-morpholino treatment L Kennedy, V Meadows, K Kyritsi, L Pham, D Kundu, R Kulkarni, ... The American Journal of Pathology 190 (5), 1018-1029, 2020 | 17 | 2020 |
The dynamic interplay between mast cells, aging/cellular senescence, and liver disease D Kundu, L Kennedy, V Meadows, L Baiocchi, G Alpini, H Francis Gene Expression 20 (2), 77, 2020 | 17 | 2020 |
Knockout of the tachykinin receptor 1 in the Mdr2−/−(Abcb4−/−) mouse model of primary sclerosing cholangitis reduces biliary damage and liver fibrosis L Ceci, H Francis, T Zhou, T Giang, Z Yang, F Meng, N Wu, L Kennedy, ... The American Journal of Pathology 190 (11), 2251-2266, 2020 | 16 | 2020 |
Melatonin receptor 1A, but not 1B, knockout decreases biliary damage and liver fibrosis during cholestatic liver injury N Wu, G Carpino, L Ceci, L Baiocchi, H Francis, L Kennedy, T Zhou, ... Hepatology 75 (4), 797-813, 2022 | 15 | 2022 |
Mast cells in liver disease progression: An update on current studies and implications L Pham, L Kennedy, L Baiocchi, V Meadows, B Ekser, D Kundu, T Zhou, ... Hepatology 75 (1), 213-218, 2022 | 14 | 2022 |