Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth CA Higgins, JC Chen, JE Cerise, CAB Jahoda, AM Christiano Proceedings of the National Academy of Sciences 110 (49), 19679-19688, 2013 | 356 | 2013 |
Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata MK Crispin, JM Ko, BG Craiglow, S Li, G Shankar, JR Urban, JC Chen, ... JCI insight 1 (15), 2016 | 344 | 2016 |
Tissue engineering of human hair follicles using a biomimetic developmental approach HE Abaci, A Coffman, Y Doucet, J Chen, J Jacków, E Wang, Z Guo, ... Nature communications 9 (1), 5301, 2018 | 227 | 2018 |
Pharmacologic inhibition of JAK-STAT signaling promotes hair growth S Harel, CA Higgins, JE Cerise, Z Dai, JC Chen, R Clynes, AM Christiano Science Advances 1 (9), e1500973, 2015 | 215 | 2015 |
Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks JC Chen, MJ Alvarez, F Talos, H Dhruv, GE Rieckhof, A Iyer, KL Diefes, ... Cell 159 (2), 402-414, 2014 | 205 | 2014 |
An open-label pilot study to evaluate the efficacy of tofacitinib in moderate to severe patch-type alopecia areata, totalis, and universalis A Jabbari, F Sansaricq, J Cerise, JC Chen, A Bitterman, G Ulerio, ... Journal of investigative dermatology 138 (7), 1539-1545, 2018 | 174 | 2018 |
Molecular signatures define alopecia areata subtypes and transcriptional biomarkers A Jabbari, JE Cerise, JC Chen, J Mackay-Wiggan, M Duvic, V Price, ... EBioMedicine 7, 240-247, 2016 | 102 | 2016 |
Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata Z Dai, J Chen, Y Chang, AM Christiano JCI insight 6 (7), 2021 | 51 | 2021 |
The tissue factor pathway and wound healing M Hoffman Seminars in thrombosis and hemostasis 44 (02), 142-150, 2018 | 41 | 2018 |
IKZF1 enhances immune infiltrate recruitment in solid tumors and susceptibility to immunotherapy JC Chen, R Perez-Lorenzo, YM Saenger, CG Drake, AM Christiano Cell Systems 7 (1), 92-103. e4, 2018 | 34 | 2018 |
Master Regulators of Infiltrate Recruitment in Autoimmune Disease Identified through Network-Based Molecular Deconvolution JC Chen, JE Cerise, A Jabbari, R Clynes, AM Christiano Cell Systems 1 (5), 326-337, 2015 | 27 | 2015 |
DIGGIT: a Bioconductor package to infer genetic variants driving cellular phenotypes MJ Alvarez, JC Chen, A Califano Bioinformatics 31 (24), 4032-4034, 2015 | 14 | 2015 |
An open-label study evaluating the efficacy of abatacept in alopecia areata J Mackay-Wiggan, BN Sallee, EHC Wang, F Sansaricq, N Nguyen, C Kim, ... Journal of the American Academy of Dermatology 84 (3), 841-844, 2021 | 13 | 2021 |
Primary cicatricial alopecias are characterized by dysregulation of shared gene expression pathways EHC Wang, I Monga, BN Sallee, JC Chen, AR Abdelaziz, ... PNAS nexus 1 (3), pgac111, 2022 | 10 | 2022 |
Pharmacologic inhibition of JAK-STAT signaling promotes hair growth. Sci Adv. 2015; 1 (9): e1500973 S Harel, CA Higgins, JE Cerise, Z Dai, JC Chen, R Clynes, AM Christiano | 7 | |
Regulatory network analysis defines unique drug mechanisms of action and facilitates patient-drug matching in alopecia areata clinical trials JC Chen, Z Dai, AM Christiano Computational and Structural Biotechnology Journal 19, 4751-4758, 2021 | 6 | 2021 |
Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata. JCI Insight. 2016; 1 (15): e89776 M Kennedy Crispin, JM Ko, BG Craiglow, S Li, G Shankar, JR Urban, ... | 5 | |
331 an open label clinical trial of the JAK inhibitor tofacitinib for alopecia areata A Jabbari, J Cerise, JC Chen, F Sansaricq, R Clynes, AM Christiano, ... Journal of Investigative Dermatology 137 (5), S56, 2017 | 3 | 2017 |
277 An open label pilot clinical trial of the JAK inhibitor tofacitinib for alopecia areata A Jabbari, J Cerise, JC Chen, G Ulerio, J Borbon, S Sidharthan, R Clynes, ... Journal of Investigative Dermatology 136 (5), S49, 2016 | 3 | 2016 |
Pharmacologic inhibition of JAK-STAT signaling promotes hair growth. Sci Adv 1 (9) S Harel, CA Higgins, JE Cerise, Z Dai, JC Chen, R Clynes, AM Christiano | 3 | 2015 |