| Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: an autophagy-like origin for virus-induced vesicles DA Suhy, TH Giddings Jr, K Kirkegaard Journal of virology 74 (19), 8953-8965, 2000 | 616 | 2000 |
| Metallothionein is part of a zinc-scavenging mechanism for cell survival under conditions of extreme zinc deprivation DA Suhy, KD Simon, DIH Linzer, TV O'Halloran Journal of Biological Chemistry 274 (14), 9183-9192, 1999 | 184 | 1999 |
| The chemical cell biology of zinc: structure and intracellular fluorescence of a zinc-quinolinesulfonamide complex MS Nasir, CJ Fahrni, DA Suhy, KJ Kolodsick, CP Singer, TV O'Halloran JBIC Journal of Biological Inorganic Chemistry 4, 775-783, 1999 | 177 | 1999 |
| PABPN1 gene therapy for oculopharyngeal muscular dystrophy A Malerba, P Klein, H Bachtarzi, SA Jarmin, G Cordova, A Ferry, V Strings, ... Nature Communications 8 (1), 14848, 2017 | 81 | 2017 |
| Safe, long-term hepatic expression of anti-HCV shRNA in a nonhuman primate model DA Suhy, SC Kao, T Mao, L Whiteley, H Denise, B Souberbielle, ... Molecular Therapy 20 (9), 1737-1749, 2012 | 69 | 2012 |
| Multiple promoter expression cassettes for simultaneous delivery of RNAi agents targeted to Hepatitis C virus PW Roelvink, DA Suhy, AA Kolykhalov US Patent 7,727,970, 2010 | 59 | 2010 |
| Metal-responsive gene regulation and the zinc metalloregulatory model. DA Suhy, TV O'Halloran Metal ions in biological systems 32, 557-578, 1996 | 31 | 1996 |
| Identification of cell surface and secreted proteins essential for tumor cell survival using a genetic suppressor element screen MS Gelman, XK Ye, R Stull, D Suhy, L Jin, D Ng, B Than, M Ji, A Pan, ... Oncogene 23 (49), 8158-8170, 2004 | 27 | 2004 |
| RNAi expression constructs with liver-specific enhancer/promoter PW Roelvink, DA Suhy, AA Kolykhalov, MA Kay, JC Giering US Patent 8,008,468, 2011 | 25 | 2011 |
| Deep sequencing insights in therapeutic shRNA processing and siRNA target cleavage precision H Denise, SA Moschos, B Sidders, F Burden, H Perkins, N Carter, ... Molecular Therapy-Nucleic Acids 3, 2014 | 23 | 2014 |
| RNAi expression constructs PW Roelvink, DA Suhy, AA Kolykhalov, L Couto US Patent 8,076,471, 2011 | 22 | 2011 |
| Double-stranded nucleic acid M Graham, K Reed, R Rice, B Harrison, P Roelvink, D Suhy, A Kolykhalov US Patent App. 10/861,191, 2005 | 18 | 2005 |
| In Vitro Characterization of the Activity of PF-05095808, a Novel Biological Agent for Hepatitis C Virus Therapy H Lavender, K Brady, F Burden, O Delpuech-Adams, H Denise, A Palmer, ... Antimicrobial agents and chemotherapy 56 (3), 1364-1375, 2012 | 17 | 2012 |
| Minigene expression cassette M Kay, M Hebert, PW Roelvink, DA Suhy US Patent 8,129,510, 2012 | 16 | 2012 |
| Device and methods for detecting and quantifying one or more target agents MR Labgold, GG Jokhadze, IMM Jen, N Shen, MT Kozlowski, CV Ammini, ... US Patent App. 11/703,103, 2009 | 16 | 2009 |
| Established PABPN1 intranuclear inclusions in OPMD muscle can be efficiently reversed by AAV-mediated knockdown and replacement of mutant expanded PABPN1 A Malerba, P Klein, N Lu-Nguyen, O Cappellari, V Strings-Ufombah, ... Human Molecular Genetics 28 (19), 3301-3308, 2019 | 13 | 2019 |
| Rnai expression constructs PW Roelvink, DA Suhy, AA Kolykhalov, L Couto US Patent App. 14/673,468, 2015 | 12 | 2015 |
| BB-301: a silence and replace AAV-based vector for the treatment of oculopharyngeal muscular dystrophy V Strings-Ufombah, A Malerba, SC Kao, S Harbaran, F Roth, O Cappellari, ... Molecular Therapy-Nucleic Acids 24, 67-78, 2021 | 11 | 2021 |
| 258. Phase I/IIa Study of TT-034, a DNA-Directed RNA Interference (ddRNAi) agent delivered as a single administration for the treatment of subjects with chronic hepatitis C … K Patel, G Kilfoil, DL Wyles, S Naggie, E Lawitz, S Bradley, P Lindell, ... Molecular Therapy 24, S102, 2016 | 10 | 2016 |
| RNAi expression constructs PW Roelvink, DA Suhy, AA Kolykhalov, L Couto US Patent 7,803,611, 2010 | 9 | 2010 |
