关注
Katerina Gurova
Katerina Gurova
Roswell Park Comprehensive Cancer Center
在 roswellpark.org 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-κB-dependent mechanism of p53 suppression in tumors
KV Gurova, JE Hill, C Guo, A Prokvolit, LG Burdelya, E Samoylova, ...
Proceedings of the National Academy of Sciences 102 (48), 17448-17453, 2005
2962005
New hopes from old drugs: revisiting DNA-binding small molecules as anticancer agents
K Gurova
Future oncology 5 (10), 1685-1704, 2009
2772009
Curaxins: anticancer compounds that simultaneously suppress NF-κB and activate p53 by targeting FACT
AV Gasparian, CA Burkhart, AA Purmal, L Brodsky, M Pal, M Saranadasa, ...
Science translational medicine 3 (95), 95ra74-95ra74, 2011
2572011
Inflammation and p53: a tale of two stresses
AV Gudkov, KV Gurova, EA Komarova
Genes & cancer 2 (4), 503-516, 2011
2102011
AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival
SS Bacus, DA Altomare, L Lyass, DM Chin, MP Farrell, K Gurova, ...
Oncogene 21 (22), 3532-3540, 2002
1992002
Facilitates chromatin transcription complex is an “accelerator” of tumor transformation and potential marker and target of aggressive cancers
H Garcia, JC Miecznikowski, A Safina, M Commane, A Ruusulehto, ...
Cell reports 4 (1), 159-173, 2013
1382013
p53 pathway in renal cell carcinoma is repressed by a dominant mechanism
KV Gurova, JE Hill, OV Razorenova, PM Chumakov, AV Gudkov
Cancer research 64 (6), 1951-1958, 2004
1382004
9-Aminoacridine-based anticancer drugs target the PI3K/AKT/mTOR, NF-κB and p53 pathways
C Guo, AV Gasparian, Z Zhuang, DA Bosykh, AA Komar, AV Gudkov, ...
Oncogene 28 (8), 1151-1161, 2009
1312009
Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma
DR Carter, J Murray, BB Cheung, L Gamble, J Koach, J Tsang, S Sutton, ...
Science translational medicine 7 (312), 312ra176-312ra176, 2015
1302015
Small-molecule multidrug resistance–associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma
CA Burkhart, F Watt, J Murray, M Pajic, A Prokvolit, C Xue, C Flemming, ...
Cancer research 69 (16), 6573-6580, 2009
1282009
Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells
H Garcia, D Fleyshman, K Kolesnikova, A Safina, M Commane, ...
Oncotarget 2 (10), 783, 2011
1132011
FACT is a sensor of DNA torsional stress in eukaryotic cells
A Safina, P Cheney, M Pal, L Brodsky, A Ivanov, K Kirsanov, E Lesovaya, ...
Nucleic acids research 45 (4), 1925-1945, 2017
1062017
Structure and function of the histone chaperone FACT–Resolving FACTual issues
K Gurova, HW Chang, ME Valieva, P Sandlesh, VM Studitsky
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1861 (9), 892-904, 2018
1012018
Mycoplasma infection suppresses p53, activates NF-κB and cooperates with oncogenic Ras in rodent fibroblast transformation
DY Logunov, DV Scheblyakov, OV Zubkova, MM Shmarov, ...
Oncogene 27 (33), 4521-4531, 2008
1012008
Targeted disruption of the mouse ing1 locus results in reduced body size, hypersensitivity to radiation and elevated incidence of lymphomas
JV Kichina, M Zeremski, L Aris, KV Gurova, E Walker, R Franks, AY Nikitin, ...
Oncogene 25 (6), 857-866, 2006
962006
Structure and regulation of the mouse ing1 gene: Three alternative transcripts encode two PHD finger proteins that have opposite effects on p53 function
M Zeremski, JE Hill, SSS Kwek, IA Grigorian, KV Gurova, IV Garkavtsev, ...
Journal of Biological Chemistry 274 (45), 32172-32181, 1999
911999
p53 determines multidrug sensitivity of childhood neuroblastoma
C Xue, M Haber, C Flemming, GM Marshall, RB Lock, KL MacKenzie, ...
Cancer research 67 (21), 10351-10360, 2007
892007
Quinacrine overcomes resistance to Erlotinib by inhibiting FACT, NF-κB, and cell-cycle progression in non–small cell lung cancer
JKT Dermawan, K Gurova, J Pink, A Dowlati, S De, G Narla, N Sharma, ...
Molecular cancer therapeutics 13 (9), 2203-2214, 2014
802014
Expression of prostate specific antigen (PSA) is negatively regulated by p53
KV Gurova, OW Roklin, VI Krivokrysenko, PM Chumakov, MB Cohen, ...
Oncogene 21 (1), 153-157, 2002
742002
Pharmacological targeting of the histone chaperone complex FACT preferentially eliminates glioblastoma stem cells and prolongs survival in preclinical models
JKT Dermawan, M Hitomi, DJ Silver, Q Wu, P Sandlesh, AE Sloan, ...
Cancer research 76 (8), 2432-2442, 2016
722016
系统目前无法执行此操作,请稍后再试。
文章 1–20