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John R Jacob
John R Jacob
Unknown affiliation
Verified email at umich.edu
Title
Cited by
Cited by
Year
NNMT silencing activates tumor suppressor PP2A, inactivates oncogenic STKs, and inhibits tumor forming ability
K Palanichamy, S Kanji, N Gordon, K Thirumoorthy, JR Jacob, ...
Clinical Cancer Research 23 (9), 2325-2334, 2017
752017
Methionine and kynurenine activate oncogenic kinases in glioblastoma, and methionine deprivation compromises proliferation
K Palanichamy, K Thirumoorthy, S Kanji, N Gordon, R Singh, JR Jacob, ...
Clinical Cancer Research 22 (14), 3513-3523, 2016
612016
Altered gemcitabine and nab-paclitaxel scheduling improves therapeutic efficacy compared with standard concurrent treatment in preclinical models of pancreatic cancer
AR Wolfe, R Robb, A Hegazi, L Abushahin, L Yang, DL Shyu, JG Trevino, ...
Clinical Cancer Research 27 (2), 554-565, 2021
102021
Lack of constitutively active DNA repair sensitizes glioblastomas to Akt inhibition and induces synthetic lethality with radiation treatment in a p53-dependent manner
K Palanichamy, D Patel, JR Jacob, KT Litzenberg, N Gordon, K Acus, ...
Molecular cancer therapeutics 17 (2), 336-346, 2018
102018
Cells isolated from residual intracranial tumors after treatment express iPSC genes and possess neural lineage differentiation plasticity
K Palanichamy, JR Jacob, KT Litzenberg, A Ray-Chaudhury, ...
EBioMedicine 36, 281-292, 2018
82018
Clinically relevant brain tumor model and device development for experimental therapeutics
K Palanichamy, K Acus, JR Jacob, A Chakravarti
Journal of Analytical Oncology 4 (1), 5-12, 2015
52015
Nicotinamide N-methyltransferase epigenetic and metabolic rewiring promotes metastatic progression
JR Jacob, A Chakravarti, K Palanichamy
Biotarget 3, 2019
12019
Mir-194-3p suppresses tumorigenic potential of glioblastoma stem cells by targeting the canonical NF-kB pathway
R Singh, K Palanichamy, JR Jacob, A Chakravarti
Cancer Research 76 (14_Supplement), 1113-1113, 2016
12016
miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition
JR Jacob, R Singh, M Okamoto, A Chakravarti, K Palanichamy
Iscience 27 (1), 2024
2024
Elucidating the Molecular Mechanisms Exploited by Glioblastoma to Evade the Tumor Suppressive Functions of Protein Phosphatase 2A
JR Jacob
The Ohio State University, 2023
2023
Nicotinamide N-methyltransferase inhibits Protein Phosphatase 2A activity by promoting Y307 phosphorylation
JR Jacob, A Chakravarti, K Palanichamy
Cancer Research 77 (13_Supplement), 2383-2383, 2017
2017
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