| Silent allosteric modulation of mGluR5 maintains glutamate signaling while rescuing Alzheimer’s mouse phenotypes LT Haas, SV Salazar, LM Smith, HR Zhao, TO Cox, CS Herber, ... Cell reports 20 (1), 76-88, 2017 | 105 | 2017 |
| Binding sites for amyloid-β oligomers and synaptic toxicity LM Smith, SM Strittmatter Cold Spring Harbor perspectives in medicine 7 (5), a024075, 2017 | 104 | 2017 |
| In vivo synaptic density imaging with 11C-UCB-J detects treatment effects of saracatinib in a mouse model of Alzheimer disease T Toyonaga, LM Smith, SJ Finnema, JD Gallezot, M Naganawa, J Bini, ... Journal of Nuclear Medicine 60 (12), 1780-1786, 2019 | 67 | 2019 |
| Systematic and standardized comparison of reported amyloid-β receptors for sufficiency, affinity, and Alzheimer's disease relevance LM Smith, MA Kostylev, S Lee, SM Strittmatter Journal of Biological Chemistry 294 (15), 6042-6053, 2019 | 63 | 2019 |
| Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy SJ Tang, A Fesharaki-Zadeh, H Takahashi, SH Nies, LM Smith, A Luo, ... Acta neuropathologica communications 8, 1-21, 2020 | 53 | 2020 |
| Disease-modifying benefit of Fyn blockade persists after washout in mouse Alzheimer's model LM Smith, R Zhu, SM Strittmatter Neuropharmacology 130, 54-61, 2018 | 48 | 2018 |
| Rescue of transgenic Alzheimer’s pathophysiology by polymeric cellular prion protein antagonists EC Gunther, LM Smith, MA Kostylev, TO Cox, AC Kaufman, S Lee, ... Cell reports 26 (1), 145-158. e8, 2019 | 42 | 2019 |
| Anti‐PrPC antibody rescues cognition and synapses in transgenic alzheimer mice TO Cox, EC Gunther, AH Brody, MT Chiasseu, A Stoner, LM Smith, ... Annals of Clinical and Translational Neurology 6 (3), 554-574, 2019 | 28 | 2019 |
| Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy AH Brody, SH Nies, F Guan, LM Smith, B Mukherjee, SA Salazar, S Lee, ... Molecular neurodegeneration 17 (1), 32, 2022 | 20 | 2022 |
| Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer’s Mouse Phenotypes. Cell Rep. 2017; 20 (1): 76-88 LT Haas, SV Salazar, LM Smith, HR Zhao, TO Cox, CS Herber, ... Epub 2017/07/07. doi: https://doi. org/10.1016/j. celrep. 2017.06. 023, 2017 | 9 | 2017 |
| High-throughput screening system for inhibitors of human Heat Shock Factor 2 LM Smith, D Bhattacharya, DJ Williams, I Dixon, NR Powell, TY Erkina, ... Cell Stress and Chaperones 20, 833-841, 2015 | 3 | 2015 |
| The new PET tracer F-18-SDM-8 effectively detects reduced SV2a binding in a rodent model of Alzheimer's disease P Sadasivam, L Smith, J Spurrier, S Lee, M Lindemann, T Toyonaga, ... JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 39, 97-97, 2019 | 1 | 2019 |
| Synaptic density imaging with 11C-UCB-J detects treatment effects of a Fyn tyrosine kinase inhibitor on Alzheimer’s disease mice. T Toyonaga, L Smith, S Finnema, JD Gallezot, M Naganawa, J Bini, Z Cai, ... Journal of Nuclear Medicine 59 (supplement 1), 197-197, 2018 | 1 | 2018 |
| Methods and compositions for the treatment of amyloid-related disorders SM Strittmatter, EC Gunther, LM Smith US Patent App. 17/258,357, 2021 | | 2021 |
| Receptors for Amyloid Beta and Pharmacologic Intervention in Alzheimer's Disease LM Smith Yale University, 2019 | | 2019 |
| Quantitative PCR using patient specific primers detects occult central nervous system involvement in more than one-third of children with acute lymphoblastic leukaemia YM Yousafzai, S Bhatti, AVE Smith, LM Smith, A Cousins, W Taylor, ... BRITISH JOURNAL OF HAEMATOLOGY 169, 13-13, 2015 | | 2015 |
| 24 ABUSED DRUG AND TOXICOLOGY MONITORING ON THE AXSYM® RANDOM ACCESS IMMUNOASSAY ANALYZER C Harrington, J Bishop, G Novak, J Douglas, N Siegel, C Azzano, ... Therapeutic Drug Monitoring 17 (4), 389, 1995 | | 1995 |
| JLFM L BARNES, Y HUANG, LM SMITH, D DURR, S LI | | |
