Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats RM Rajani, S Quick, SR Ruigrok, D Graham, SE Harris, BFJ Verhaaren, ... Science translational medicine 10 (448), eaam9507, 2018 | 170 | 2018 |
Early-life stress lastingly alters the neuroinflammatory response to amyloid pathology in an Alzheimer’s disease mouse model L Hoeijmakers, SR Ruigrok, A Amelianchik, D Ivan, AM van Dam, ... Brain, behavior, and immunity 63, 160-175, 2017 | 134 | 2017 |
Ghrelin and hypothalamic NPY/AgRP expression in mice are affected by chronic early-life stress exposure in a sex-specific manner KY Yam, SR Ruigrok, I Ziko, SN De Luca, PJ Lucassen, SJ Spencer, ... Psychoneuroendocrinology 86, 73-77, 2017 | 46 | 2017 |
Increasing availability of ω‐3 fatty acid in the early‐life diet prevents the early‐life stress‐induced cognitive impairments without affecting metabolic alterations KY Yam, L Schipper, K Reemst, SR Ruigrok, MR Abbink, L Hoeijmakers, ... The FASEB Journal 33 (4), 5729-5740, 2019 | 43 | 2019 |
Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation JM van der Harg, L Eggels, FN Bangel, SR Ruigrok, R Zwart, ... Neurobiology of Disease 103, 163-173, 2017 | 32 | 2017 |
Early signature in the blood lipidome associated with subsequent cognitive decline in the elderly: A case-control analysis nested within the Three-City cohort study S Lefevre-Arbogast, BP Hejblum, C Helmer, C Klose, C Manach, DY Low, ... EBioMedicine 64, 103216, 2021 | 21 | 2021 |
Effects of early-life stress on peripheral and central mitochondria in male mice across ages SR Ruigrok, K Yim, TL Emmerzaal, B Geenen, N Stöberl, ... Psychoneuroendocrinology 132, 105346, 2021 | 20 | 2021 |
Food and Microbiota Metabolites Associate with Cognitive Decline in Older Subjects: A 12‐Year Prospective Study R González‐Domínguez, P Castellano‐Escuder, F Carmona, ... Molecular nutrition & food research 65 (23), 2100606, 2021 | 19 | 2021 |
Exploration of the Gut–Brain Axis through Metabolomics Identifies Serum Propionic Acid Associated with Higher Cognitive Decline in Older Persons J Neuffer, R González-Domínguez, S Lefèvre-Arbogast, DY Low, ... Nutrients 14 (21), 4688, 2022 | 16 | 2022 |
Effects of early-life stress, postnatal diet modulation and long-term western-style diet on peripheral and central inflammatory markers SR Ruigrok, MR Abbink, J Geertsema, JE Kuindersma, N Stöberl, ... Nutrients 13 (2), 288, 2021 | 15 | 2021 |
Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline R González-Domínguez, P Castellano-Escuder, S Lefèvre-Arbogast, ... Alzheimer's research & therapy 14 (1), 1-12, 2022 | 14 | 2022 |
Neuroinflammation is not a Prerequisite for Diabetes-induced Tau Phosphorylation JM Van der Harg, L Eggels, SR Ruigrok, JJM Hoozemans, SE La Fleur, ... Frontiers in neuroscience 9, 432, 2015 | 14 | 2015 |
The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia A Du Preez, S Lefèvre‐Arbogast, V Houghton, C De Lucia, DY Low, ... Alzheimer's & Dementia 18 (4), 654-675, 2022 | 13 | 2022 |
Adult food choices depend on sex and exposure to early-life stress: Underlying brain circuitry, adipose tissue adaptations and metabolic responses SR Ruigrok, JM Kotah, JE Kuindersma, E Speijer, AAS van Irsen, ... Neurobiology of stress 15, 100360, 2021 | 13 | 2021 |
Caffeine compromises proliferation of human hippocampal progenitor cells V Houghton, A Du Preez, S Lefèvre-Arbogast, C De Lucia, DY Low, ... Frontiers in cell and developmental biology, 806, 2020 | 11 | 2020 |
Sex-dependence and comorbidities of the early-life adversity induced mental and metabolic disease risks: where are we at? K Reemst, SR Ruigrok, L Bleker, E Naninck, T Ernst, J Kotah, ... Neuroscience & Biobehavioral Reviews, 104627, 2022 | 10 | 2022 |
Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study A Du Preez, S Lefèvre-Arbogast, R González-Domínguez, V Houghton, ... Molecular Psychiatry, 1-16, 2022 | 9 | 2022 |
Modulation of the Hypothalamic Nutrient Sensing Pathways by Sex and Early-Life Stress SR Ruigrok, N Stöberl, KY Yam, C De Lucia, PJ Lucassen, S Thuret, ... Frontiers in neuroscience, 914, 2021 | 9 | 2021 |
The age-related slow increase in amyloid pathology in APP. V717I mice activates microglia, but does not alter hippocampal neurogenesis L Hoeijmakers, GF Meerhoff, JW de Vries, SR Ruigrok, AM van Dam, ... Neurobiology of Aging 61, 112-123, 2018 | 9 | 2018 |
Metabolic programming by early-life stress exposure: Focus on sex differences SR Ruigrok | | 2021 |