Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T-cell dysfunction N Singh, YG Lee, O Shestova, P Ravikumar, KE Hayer, SJ Hong, XM Lu, ... Cancer discovery 10 (4), 552-567, 2020 | 221 | 2020 |
An NK-like CAR T cell transition in CAR T cell dysfunction CR Good, MA Aznar, S Kuramitsu, P Samareh, S Agarwal, G Donahue, ... Cell 184 (25), 6081-6100. e26, 2021 | 202 | 2021 |
TET1-mediated hypomethylation activates oncogenic signaling in triple-negative breast cancer CR Good, S Panjarian, AD Kelly, J Madzo, B Patel, J Jelinek, JPJ Issa Cancer research 78 (15), 4126-4137, 2018 | 114 | 2018 |
A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer CR Good, J Madzo, B Patel, S Maegawa, N Engel, J Jelinek, JPJ Issa Nucleic Acids Research 45 (14), 8269-8281, 2017 | 68 | 2017 |
p53 mediates target gene association with nuclear speckles for amplified RNA expression KA Alexander, A Coté, SC Nguyen, L Zhang, O Gholamalamdari, ... Molecular cell 81 (8), 1666-1681. e6, 2021 | 61 | 2021 |
Reverse transcriptase inhibition disrupts repeat element life cycle in colorectal cancer M Rajurkar, AR Parikh, A Solovyov, E You, AS Kulkarni, C Chu, KH Xu, ... Cancer discovery 12 (6), 1462-1481, 2022 | 31 | 2022 |
Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor T cells S Agarwal, MA Aznar, AJ Rech, CR Good, S Kuramitsu, T Da, M Gohil, ... Immunity 56 (10), 2388-2407. e9, 2023 | 25 | 2023 |
Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks AN Catizone, CR Good, KA Alexander, SL Berger, MA Sammons Cell Cycle 18 (8), 809-823, 2019 | 11 | 2019 |
Demethylator phenotypes in acute myeloid leukemia AD Kelly, J Madzo, P Madireddi, P Kropf, CR Good, J Jelinek, JPJ Issa Leukemia 32 (10), 2178-2188, 2018 | 9 | 2018 |
Histone acetylation in an Alzheimer’s disease cell model promotes homeostatic amyloid-reducing pathways DC Xu, H Sas-Nowosielska, G Donahue, H Huang, N Pourshafie, ... Acta Neuropathologica Communications 12 (1), 3, 2024 | 3 | 2024 |
TOX2 coordinates with TET2 to positively regulate central memory differentiation in human CAR T cells SM Collins, KA Alexander, S Lundh, AJ Dimitri, Z Zhang, CR Good, ... Science Advances 9 (29), eadh2605, 2023 | 2 | 2023 |
Impaired tumor death receptor signaling drives resistance to CAR T cell therapy N Singh, O Shestova, P Ravikumar, KE Hayer, SJ Hong, EJ Orlando, ... bioRxiv, 627562, 2019 | 2 | 2019 |
Induction of T cell dysfunction and NK-like T cell differentiation in vitro and in patients after CAR T cell treatment CR Good, S Kuramitsu, P Samareh, G Donahue, K Ishiyama, Y Ma, ... Cancer Research 81 (13_Supplement), 60-60, 2021 | 1 | 2021 |
Compositions and methods for assessing and treating t cell dysfunction CH June, RM Young, SL Berger, CR Good, MAA Gomez, S Kuramitsu US Patent App. 18/549,252, 2024 | | 2024 |
Mechanisms of CAR T cell dysfunction and identification of transcription factors that drive the exhaustion phenotype MA Aznar, CR Good, S Kuramitsu, P Samareh, S Agarwal, G Donahue, ... Cancer Research 82 (12_Supplement), 3602-3602, 2022 | | 2022 |
RESEARCH WATCH CR Good, MA Aznar, S Kuramitsu, P Samareh, S Agarwal, G Donahue cancer. Immunity 54, 2812-24, 2021 | | 2021 |
The role of TET1 and TET1ALT in cancer CR Good Theses and Dissertations, 2017 | | 2017 |