Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis D Cai, S Yin, J Yang, Q Jiang, W Cao Arthritis research & therapy 17, 1-11, 2015 | 149 | 2015 |
Rhein reverses Klotho repression via promoter demethylation and protects against kidney and bone injuries in mice with chronic kidney disease Q Zhang, L Liu, W Lin, S Yin, A Duan, Z Liu, W Cao Kidney international 91 (1), 144-156, 2017 | 117 | 2017 |
Toll-like receptor signaling induces Nrf2 pathway activation through p62-triggered Keap1 degradation S Yin, W Cao Molecular and cellular biology 35 (15), 2673-2683, 2015 | 92 | 2015 |
Sinomenine activation of Nrf2 signaling prevents hyperactive inflammation and kidney injury in a mouse model of obstructive nephropathy T Qin, R Du, F Huang, S Yin, J Yang, S Qin, W Cao Free Radical Biology and Medicine 92, 90-99, 2016 | 86 | 2016 |
TGFβ-incurred epigenetic aberrations of miRNA and DNA methyltransferase suppress Klotho and potentiate renal fibrosis S Yin, Q Zhang, J Yang, W Lin, Y Li, F Chen, W Cao Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (7), 1207-1216, 2017 | 82 | 2017 |
Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase-1 Y Jeong, R Du, X Zhu, S Yin, J Wang, H Cui, W Cao, CJ Lowenstein Journal of leukocyte biology 95 (4), 651-659, 2014 | 81 | 2014 |
LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control W Gan, X Dai, X Dai, J Xie, S Yin, J Zhu, C Wang, Y Liu, J Guo, M Wang, ... Nature cell biology 22 (2), 246-256, 2020 | 69 | 2020 |
Sinomenine attenuates renal fibrosis through Nrf2-mediated inhibition of oxidative stress and TGFβ signaling T Qin, S Yin, J Yang, Q Zhang, Y Liu, F Huang, W Cao Toxicology and applied pharmacology 304, 1-8, 2016 | 68 | 2016 |
Klotho restoration via acetylation of peroxisome proliferation–activated receptor γ reduces the progression of chronic kidney disease W Lin, Q Zhang, L Liu, S Yin, Z Liu, W Cao Kidney international 92 (3), 669-679, 2017 | 66 | 2017 |
Rhein reversal of DNA hypermethylation-associated Klotho suppression ameliorates renal fibrosis in mice Q Zhang, S Yin, L Liu, Z Liu, W Cao Scientific Reports 6 (1), 34597, 2016 | 59 | 2016 |
Hypoxia induces an endometrial cancer stem-like cell phenotype via HIF-dependent demethylation of SOX2 mRNA G Chen, B Liu, S Yin, S Li, Y Guo, M Wang, K Wang, X Wan Oncogenesis 9 (9), 81, 2020 | 57 | 2020 |
Nrf2 is essential for the anti-inflammatory effect of carbon monoxide in LPS-induced inflammation SY Qin, RH Du, SS Yin, XF Liu, GL Xu, W Cao Inflammation Research 64, 537-548, 2015 | 57 | 2015 |
Klotho recovery by genistein via promoter histone acetylation and DNA demethylation mitigates renal fibrosis in mice Y Li, F Chen, A Wei, F Bi, X Zhu, S Yin, W Lin, W Cao Journal of Molecular Medicine 97, 541-552, 2019 | 54 | 2019 |
PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis S Yin, L Liu, C Brobbey, V Palanisamy, LE Ball, SK Olsen, MC Ostrowski, ... Nature communications 12 (1), 3444, 2021 | 50 | 2021 |
Klotho preservation via histone deacetylase inhibition attenuates chronic kidney disease-associated bone injury in mice W Lin, Y Li, F Chen, S Yin, Z Liu, W Cao Scientific reports 7 (1), 46195, 2017 | 48 | 2017 |
Heme oxygenase-1 induction attenuates imiquimod-induced psoriasiform inflammation by negative regulation of Stat3 signaling B Zhang, S Xie, Z Su, S Song, H Xu, G Chen, W Cao, S Yin, Q Gao, ... Scientific Reports 6 (1), 21132, 2016 | 48 | 2016 |
TIMAP repression by TGFβ and HDAC3-associated Smad signaling regulates macrophage M2 phenotypic phagocytosis J Yang, S Yin, F Bi, L Liu, T Qin, H Wang, W Cao Journal of Molecular Medicine 95, 273-285, 2017 | 24 | 2017 |
The role of protein arginine methyltransferases in DNA damage response C Brobbey, L Liu, S Yin, W Gan International Journal of Molecular Sciences 23 (17), 9780, 2022 | 21 | 2022 |
The roles of post-translational modifications on mTOR signaling S Yin, L Liu, W Gan International Journal of Molecular Sciences 22 (4), 1784, 2021 | 20 | 2021 |
DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway L Liu, X Dai, S Yin, P Liu, EG Hill, W Wei, W Gan Science signaling 15 (715), eabh2290, 2022 | 17 | 2022 |