| The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation R Hashizume, M Fukuda, I Maeda, H Nishikawa, D Oyake, Y Yabuki, ... Journal of Biological Chemistry 276 (18), 14537-14540, 2001 | 882 | 2001 |
| ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity T Ohta, JJ Michel, AJ Schottelius, Y Xiong Molecular cell 3 (4), 535-541, 1999 | 591 | 1999 |
| Targeted ubiquitination of CDT1 by the DDB1–CUL4A–ROC1 ligase in response to DNA damage J Hu, CM McCall, T Ohta, Y Xiong Nature cell biology 6 (10), 1003-1009, 2004 | 407 | 2004 |
| Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex PS Brzovic, JR Keeffe, H Nishikawa, K Miyamoto, D Fox III, M Fukuda, ... Proceedings of the National Academy of Sciences 100 (10), 5646-5651, 2003 | 397 | 2003 |
| Stem-loop binding protein, the protein that binds the 3′ end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms ML Whitfield, LX Zheng, A Baldwin, T Ohta, MM Hurt, WF Marzluff Molecular and cellular biology 20 (12), 4188-4198, 2000 | 317 | 2000 |
| Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase H Nishikawa, S Ooka, K Sato, K Arima, J Okamoto, RE Klevit, M Fukuda, ... Journal of Biological Chemistry 279 (6), 3916-3924, 2004 | 313 | 2004 |
| BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity H Nishikawa, W Wu, A Koike, R Kojima, H Gomi, M Fukuda, T Ohta Cancer research 69 (1), 111-119, 2009 | 265 | 2009 |
| Cytoplasmic destruction of p53 by the endoplasmic reticulum‐resident ubiquitin ligase ‘Synoviolin’ S Yamasaki, N Yagishita, T Sasaki, M Nakazawa, Y Kato, T Yamadera, ... The EMBO journal 26 (1), 113-122, 2007 | 228 | 2007 |
| Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase K Sato, R Hayami, W Wu, T Nishikawa, H Nishikawa, Y Okuda, H Ogata, ... Journal of Biological Chemistry 279 (30), 30919-30922, 2004 | 190 | 2004 |
| Ubiquitin acetylation inhibits polyubiquitin chain elongation F Ohtake, Y Saeki, K Sakamoto, K Ohtake, H Nishikawa, H Tsuchiya, ... EMBO reports 16 (2), 192-201, 2015 | 183 | 2015 |
| Ubiquitin and breast cancer T Ohta, M Fukuda Oncogene 23 (11), 2079-2088, 2004 | 182 | 2004 |
| The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1 M Furukawa, Y Zhang, J McCarville, T Ohta, Y Xiong Molecular and cellular biology 20 (21), 8185-8197, 2000 | 180 | 2000 |
| Involvement of kinesin family member 2C/mitotic centromere‐associated kinesin overexpression in mammary carcinogenesis A Shimo, C Tanikawa, T Nishidate, ML Lin, K Matsuda, JH Park, T Ueki, ... Cancer science 99 (1), 62-70, 2008 | 171 | 2008 |
| A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair N Matsushita, H Kitao, M Ishiai, N Nagashima, S Hirano, K Okawa, T Ohta, ... Molecular cell 19 (6), 841-847, 2005 | 171 | 2005 |
| HERC2 is an E3 ligase that targets BRCA1 for degradation W Wu, K Sato, A Koike, H Nishikawa, H Koizumi, AR Venkitaraman, ... Cancer research 70 (15), 6384-6392, 2010 | 155 | 2010 |
| The ubiquitin E3 ligase activity of BRCA1 and its biological functions W Wu, A Koike, T Takeshita, T Ohta Cell division 3, 1-10, 2008 | 149 | 2008 |
| Essential role of synoviolin in embryogenesis N Yagishita, K Ohneda, T Amano, S Yamasaki, A Sugiura, K Tsuchimochi, ... Journal of Biological Chemistry 280 (9), 7909-7916, 2005 | 124 | 2005 |
| Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates A Koike, H Nishikawa, W Wu, Y Okada, AR Venkitaraman, T Ohta Cancer research 70 (17), 6746-6756, 2010 | 122 | 2010 |
| Expression of β‐catenin in normal breast tissue and breast carcinoma: a comparative study with epithelial cadherin and α‐catenin R Hashizume, H Koizumi, A Ihara, T Ohta, T Uchikoshi Histopathology 29 (2), 139-146, 1996 | 122 | 1996 |
| Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells A Shimo, T Nishidate, T Ohta, M Fukuda, Y Nakamura, T Katagiri Cancer Science 98 (2), 174-181, 2007 | 116 | 2007 |
