| Growthcurver: an R package for obtaining interpretable metrics from microbial growth curves K Sprouffske, A Wagner BMC bioinformatics 17, 1-4, 2016 | 642 | 2016 |
| Cancer in light of experimental evolution K Sprouffske, LMF Merlo, PJ Gerrish, CC Maley, PD Sniegowski Current Biology 22 (17), R762-R771, 2012 | 108 | 2012 |
| Fast NMDA Receptor–Mediated Synaptic Currents in Neurons From Mice Lacking the ε2 (NR2B) Subunit KR Tovar, K Sprouffske, GL Westbrook Journal of neurophysiology 83 (1), 616-620, 2000 | 105 | 2000 |
| High mutation rates limit evolutionary adaptation in Escherichia coli K Sprouffske, J Aguilar-Rodríguez, P Sniegowski, A Wagner PLoS genetics 14 (4), e1007324, 2018 | 96 | 2018 |
| Animal cell differentiation patterns suppress somatic evolution JW Pepper, K Sprouffske, CC Maley PLoS computational biology 3 (12), e250, 2007 | 91 | 2007 |
| Accurate reconstruction of the temporal order of mutations in neoplastic progression K Sprouffske, JW Pepper, CC Maley Cancer prevention research 4, 1135-1144, 2011 | 81 | 2011 |
| Solving the puzzle of metastasis: the evolution of cell migration in neoplasms J Chen, K Sprouffske, Q Huang, CC Maley PloS one 6 (4), e17933, 2011 | 80 | 2011 |
| PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma M Bleu, S Gaulis, R Lopes, K Sprouffske, V Apfel, S Holwerda, ... Nature communications 10 (1), 3739, 2019 | 53 | 2019 |
| The SIB Swiss Institute of Bioinformatics’ resources: focus on curated databases SIB Swiss Institute of Bioinformatics Members Nucleic acids research 44 (D1), D27-D37, 2016 | 51 | 2016 |
| Assessing the benefits of horizontal gene transfer by laboratory evolution and genome sequencing HY Chu, K Sprouffske, A Wagner BMC evolutionary biology 18 (1), 54, 2018 | 40 | 2018 |
| An evolutionary explanation for the presence of cancer nonstem cells in neoplasms K Sprouffske, C Athena Aktipis, JP Radich, M Carroll, AM Nedelcu, ... Evolutionary applications 6 (1), 92-101, 2013 | 37 | 2013 |
| Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens R Lopes, K Sprouffske, C Sheng, ECH Uijttewaal, AE Wesdorp, ... Science advances 7 (27), eabf5733, 2021 | 27 | 2021 |
| Peto's paradox revisited: theoretical evolutionary dynamics of cancer in wild populations B Roche, K Sprouffske, H Hbid, D Misse, F Thomas Evolutionary Applications 6 (1), 109-116, 2013 | 27 | 2013 |
| Exquisite sensitivity to dual BRG1/BRM ATPase inhibitors reveals broad SWI/SNF dependencies in acute myeloid leukemia F Rago, LU Rodrigues, M Bonney, K Sprouffske, E Kurth, GN Elliott, ... Molecular cancer research 20 (3), 361-372, 2022 | 24 | 2022 |
| growthcurver: Simple metrics to summarize growth curves K Sprouffske R package version 0.3 1, 2020 | 23 | 2020 |
| How Archiving by Freezing Affects the Genome-Scale Diversity of Escherichia coli Populations K Sprouffske, J Aguilar-Rodríguez, A Wagner Genome biology and evolution 8 (5), 1290-1298, 2016 | 23 | 2016 |
| The discovery of SWI/SNF chromatin remodeling activity as a novel and targetable dependency in uveal melanoma F Rago, GN Elliott, A Li, K Sprouffske, G Kerr, A Desplat, D Abramowski, ... Molecular cancer therapeutics 19 (10), 2186-2195, 2020 | 19 | 2020 |
| Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models K Sprouffske, G Kerr, C Li, A Prahallad, R Rebmann, V Waehle, ... Computational and structural biotechnology journal 18, 323-331, 2020 | 18 | 2020 |
| The role of recombination in evolutionary adaptation of Escherichia coli to a novel nutrient HY Chu, K Sprouffske, A Wagner Journal of evolutionary biology 30 (9), 1692-1711, 2017 | 11 | 2017 |
| Effect of population size and mutation rate on the evolution of RNA sequences on an adaptive landscape determined by RNA folding AR Vahdati, K Sprouffske, A Wagner International journal of biological sciences 13 (9), 1138, 2017 | 10 | 2017 |
Andreas WagnerUniversity of ZurichVerified email at ieu.uzh.ch
