A human disease-causing point mutation in mitochondrial threonyl-tRNA synthetase induces both structural and functional defects Y Wang, XL Zhou, ZR Ruan, RJ Liu, G Eriani, ED Wang Journal of Biological Chemistry 291 (12), 6507-6520, 2016 | 48 | 2016 |
A deafness-associated tRNAAsp mutation alters the m1G37 modification, aminoacylation and stability of tRNAAsp and mitochondrial function M Wang, Y Peng, J Zheng, B Zheng, X Jin, H Liu, Y Wang, X Tang, ... Nucleic acids research 44 (22), 10974-10985, 2016 | 42 | 2016 |
Mutations in KARS cause early‐onset hearing loss and leukoencephalopathy: Potential pathogenic mechanism XL Zhou, LX He, LJ Yu, Y Wang, XJ Wang, ED Wang, T Yang Human Mutation 38 (12), 1740-1750, 2017 | 31 | 2017 |
A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities Y Chen, ZR Ruan, Y Wang, Q Huang, MQ Xue, XL Zhou, ED Wang Nucleic acids research 46 (7), 3643-3656, 2018 | 30 | 2018 |
Molecular basis for t6A modification in human mitochondria JB Zhou, Y Wang, QY Zeng, SX Meng, ED Wang, XL Zhou Nucleic Acids Research 48 (6), 3181-3194, 2020 | 26 | 2020 |
A minimalist mitochondrial threonyl-tRNA synthetase exhibits tRNA-isoacceptor specificity during proofreading XL Zhou, ZR Ruan, M Wang, ZP Fang, Y Wang, Y Chen, RJ Liu, G Eriani, ... Nucleic acids research 42 (22), 13873-13886, 2014 | 24 | 2014 |
Hearing impairment-associated KARS mutations lead to defects in aminoacylation of both cytoplasmic and mitochondrial tRNALys Y Wang, JB Zhou, QY Zeng, S Wu, MQ Xue, P Fang, ED Wang, XL Zhou Science China Life Sciences 63, 1227-1239, 2020 | 22 | 2020 |
A natural non-Watson–Crick base pair in human mitochondrial tRNAThr causes structural and functional susceptibility to local mutations Y Wang, QY Zeng, WQ Zheng, QQ Ji, XL Zhou, ED Wang Nucleic acids research 46 (9), 4662-4676, 2018 | 21 | 2018 |
Translational quality control by bacterial threonyl-tRNA synthetases XL Zhou, Y Chen, ZP Fang, ZR Ruan, Y Wang, RJ Liu, MQ Xue, ED Wang Journal of Biological Chemistry 291 (40), 21208-21221, 2016 | 20 | 2016 |
ZMYND8 is a master regulator of 27-hydroxycholesterol that promotes tumorigenicity of breast cancer stem cells M Luo, L Bao, Y Chen, Y Xue, Y Wang, B Zhang, C Wang, CD Corley, ... Science Advances 8 (28), eabn5295, 2022 | 11 | 2022 |
ZMYND8 expression in breast cancer cells blocks T-lymphocyte surveillance to promote tumor growth Y Wang, M Luo, Y Chen, Y Wang, B Zhang, Z Ren, L Bao, Y Wang, ... Cancer research 81 (1), 174-186, 2021 | 11 | 2021 |