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YONG WANG
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A human disease-causing point mutation in mitochondrial threonyl-tRNA synthetase induces both structural and functional defects
Y Wang, XL Zhou, ZR Ruan, RJ Liu, G Eriani, ED Wang
Journal of Biological Chemistry 291 (12), 6507-6520, 2016
482016
A deafness-associated tRNAAsp mutation alters the m1G37 modification, aminoacylation and stability of tRNAAsp and mitochondrial function
M Wang, Y Peng, J Zheng, B Zheng, X Jin, H Liu, Y Wang, X Tang, ...
Nucleic acids research 44 (22), 10974-10985, 2016
422016
Mutations in KARS cause early‐onset hearing loss and leukoencephalopathy: Potential pathogenic mechanism
XL Zhou, LX He, LJ Yu, Y Wang, XJ Wang, ED Wang, T Yang
Human Mutation 38 (12), 1740-1750, 2017
312017
A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities
Y Chen, ZR Ruan, Y Wang, Q Huang, MQ Xue, XL Zhou, ED Wang
Nucleic acids research 46 (7), 3643-3656, 2018
302018
Molecular basis for t6A modification in human mitochondria
JB Zhou, Y Wang, QY Zeng, SX Meng, ED Wang, XL Zhou
Nucleic Acids Research 48 (6), 3181-3194, 2020
262020
A minimalist mitochondrial threonyl-tRNA synthetase exhibits tRNA-isoacceptor specificity during proofreading
XL Zhou, ZR Ruan, M Wang, ZP Fang, Y Wang, Y Chen, RJ Liu, G Eriani, ...
Nucleic acids research 42 (22), 13873-13886, 2014
242014
Hearing impairment-associated KARS mutations lead to defects in aminoacylation of both cytoplasmic and mitochondrial tRNALys
Y Wang, JB Zhou, QY Zeng, S Wu, MQ Xue, P Fang, ED Wang, XL Zhou
Science China Life Sciences 63, 1227-1239, 2020
222020
A natural non-Watson–Crick base pair in human mitochondrial tRNAThr causes structural and functional susceptibility to local mutations
Y Wang, QY Zeng, WQ Zheng, QQ Ji, XL Zhou, ED Wang
Nucleic acids research 46 (9), 4662-4676, 2018
212018
Translational quality control by bacterial threonyl-tRNA synthetases
XL Zhou, Y Chen, ZP Fang, ZR Ruan, Y Wang, RJ Liu, MQ Xue, ED Wang
Journal of Biological Chemistry 291 (40), 21208-21221, 2016
202016
ZMYND8 is a master regulator of 27-hydroxycholesterol that promotes tumorigenicity of breast cancer stem cells
M Luo, L Bao, Y Chen, Y Xue, Y Wang, B Zhang, C Wang, CD Corley, ...
Science Advances 8 (28), eabn5295, 2022
112022
ZMYND8 expression in breast cancer cells blocks T-lymphocyte surveillance to promote tumor growth
Y Wang, M Luo, Y Chen, Y Wang, B Zhang, Z Ren, L Bao, Y Wang, ...
Cancer research 81 (1), 174-186, 2021
112021
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