| Awakening guardian angels: drugging the p53 pathway CJ Brown, S Lain, CS Verma, AR Fersht, DP Lane Nature Reviews Cancer 9 (12), 862-873, 2009 | 1093 | 2009 |
| Highlights and prospects of potyvirus molecular biology JL Riechmann, S Lain, JA García Journal of General Virology 73 (1), 1-16, 1992 | 853 | 1992 |
| SUMO‐1 modification activates the transcriptional response of p53 MS Rodriguez, JMP Desterro, S Lain, CA Midgley, DP Lane, RT Hay The EMBO journal, 1999 | 838 | 1999 |
| Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator S Lain, JJ Hollick, J Campbell, OD Staples, M Higgins, M Aoubala, ... Cancer cell 13 (5), 454-463, 2008 | 594 | 2008 |
| Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation MS Rodriguez, JMP Desterro, S Lain, DP Lane, RT Hay Molecular and cellular biology 20 (22), 8458-8467, 2000 | 534 | 2000 |
| P53 abnormalities and outcomes in colorectal cancer: a systematic review AJ Munro, S Lain, DP Lane British journal of cancer 92 (3), 434-444, 2005 | 372 | 2005 |
| p53-based cancer therapy DP Lane, CF Cheok, S Lain Cold Spring Harbor perspectives in biology 2 (9), a001222, 2010 | 342 | 2010 |
| Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90RSK and cAMP-dependent protein kinase, but not its farnesylation at … GP Sapkota, A Kieloch, JM Lizcano, S Lain, JSC Arthur, MR Williams, ... Journal of Biological Chemistry 276 (22), 19469-19482, 2001 | 318 | 2001 |
| Activation of p53 in cervical carcinoma cells by small molecules S Hietanen, S Lain, E Krausz, C Blattner, DP Lane Proceedings of the National Academy of Sciences 97 (15), 8501-8506, 2000 | 299 | 2000 |
| RNA helicase: a novel activity associated with a protein encoded by a positive strand RNA virus S Lain, JL Riechmann, JA Garcia Nucleic acids research 18 (23), 7003-7006, 1990 | 294 | 1990 |
| Acetylation site specificities of lysine deacetylase inhibitors in human cells C Schölz, BT Weinert, SA Wagner, P Beli, Y Miyake, J Qi, LJ Jensen, ... Nature biotechnology 33 (4), 415-423, 2015 | 270 | 2015 |
| SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells L Li, T Osdal, Y Ho, S Chun, T McDonald, P Agarwal, A Lin, S Chu, J Qi, ... Cell stem cell 15 (4), 431-446, 2014 | 235 | 2014 |
| Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide from p16CDKN2/INK4A R Fåhraeus, JM Paramio, KL Ball, S Laín, DP Lane Current Biology 6 (1), 84-91, 1996 | 232 | 1996 |
| Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1 KL Ball, S Lain, R Fåhraeus, C Smythe, DP Lane Current Biology 7 (1), 71-80, 1997 | 218 | 1997 |
| An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs S Laı́n, C Midgley, A Sparks, EB Lane, DP Lane Experimental cell research 248 (2), 457-472, 1999 | 213 | 1999 |
| Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo D Xirodimas, MK Saville, C Edling, DP Lane, S Lain Oncogene 20 (36), 4972-4983, 2001 | 207 | 2001 |
| The complete nucleotide sequence of plum pox potyvirus RNA S Laín, JL Riechmann, JA García Virus research 13 (2), 157-172, 1989 | 188 | 1989 |
| Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain S Yadavilli, LD Mayo, M Higgins, S Lain, V Hegde, WA Deutsch DNA repair 8 (10), 1215-1224, 2009 | 179 | 2009 |
| Therapeutic exploitation of the p53 pathway DP Lane, S Lain Trends in molecular medicine 8 (4), S38-S42, 2002 | 173 | 2002 |
| Novel catalytic activity associated with positive-strand RNA virus infection: nucleic acid-stimulated ATPase activity of the plum pox potyvirus helicaselike protein S Lain, MT Martin, JL Riechmann, JA Garcia Journal of virology 65 (1), 1-6, 1991 | 167 | 1991 |
