Cancer-associated protein kinase C mutations reveal kinase’s role as tumor suppressor CE Antal, AM Hudson, E Kang, C Zanca, C Wirth, NL Stephenson, ... Cell 160 (3), 489-502, 2015 | 352 | 2015 |
Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors AA Marusiak, ZC Edwards, W Hugo, EW Trotter, MR Girotti, ... Nature communications 5 (1), 3901, 2014 | 86 | 2014 |
What three wise men have to say about diagnosis N Mani, N Slevin, A Hudson BMJ 343, 2011 | 50 | 2011 |
Somatic insulin signaling regulates a germline starvation response in Drosophila egg chambers KM Burn, Y Shimada, K Ayers, S Vemuganti, F Lu, AM Hudson, L Cooley Developmental biology 398 (2), 206-217, 2015 | 44 | 2015 |
Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery AM Hudson, T Yates, Y Li, EW Trotter, S Fawdar, P Chapman, P Lorigan, ... Cancer research 74 (22), 6390-6396, 2014 | 40 | 2014 |
Somatically mutated ABL 1 is an actionable and essential NSCLC survival gene E Testoni, NL Stephenson, P Torres‐Ayuso, AA Marusiak, EW Trotter, ... EMBO molecular medicine 8 (2), 105-116, 2016 | 27 | 2016 |
Actin Cytoskeletal Organization in Drosophila Germline Ring Canals Depends on Kelch Function in a Cullin-RING E3 Ligase AM Hudson, KM Mannix, L Cooley Genetics 201 (3), 1117-1131, 2015 | 27 | 2015 |
Is heterogeneity in stage 3 non-small cell lung cancer obscuring the potential benefits of dose-escalated concurrent chemo-radiotherapy in clinical trials? A Hudson, C Chan, D Woolf, A McWilliam, C Hiley, J O’Connor, ... Lung Cancer 118, 139-147, 2018 | 15 | 2018 |
Truncation-and motif-based pan-cancer analysis reveals tumor-suppressing kinases AM Hudson, NL Stephenson, C Li, E Trotter, AJ Fletcher, G Katona, ... Science signaling 11 (526), eaan6776, 2018 | 14 | 2018 |
Using large-scale genomics data to identify driver mutations in lung cancer: methods and challenges AM Hudson, C Wirth, NL Stephenson, S Fawdar, J Brognard, CJ Miller Pharmacogenomics 16 (10), 1149-1160, 2015 | 14 | 2015 |
HtsRC-Mediated Accumulation of F-Actin Regulates Ring Canal Size During Drosophila melanogaster Oogenesis JA Gerdes, KM Mannix, AM Hudson, L Cooley Genetics 216 (3), 717-734, 2020 | 12 | 2020 |
Palliative lung radiotherapy: higher dose leads to improved survival? TS Lewis, JA Kennedy, GJ Price, T Mee, DK Woolf, NA Bayman, C Chan, ... Clinical Oncology 32 (10), 674-684, 2020 | 12 | 2020 |
Tissue-specific dynamic codon redefinition in Drosophila AM Hudson, NL Szabo, G Loughran, NM Wills, JF Atkins, L Cooley Proceedings of the National Academy of Sciences 118 (5), e2012793118, 2021 | 11 | 2021 |
Expanded access programmes: patient interests versus clinical trial integrity P Lorigan, PA Ascierto, R Dummer, AM Eggermont, KT Flaherty, C Garbe, ... The Lancet Oncology 16 (1), 15-17, 2015 | 10 | 2015 |
Targeted substrate degradation by Kelch controls the actin cytoskeleton during ring canal expansion AM Hudson, KM Mannix, JA Gerdes, MC Kottemann, L Cooley Development 146 (1), dev169219, 2019 | 9 | 2019 |
Impact of introducing intensity modulated radiotherapy on curative intent radiotherapy and survival for lung cancer I Fornacon-Wood, C Chan, N Bayman, K Banfill, J Coote, A Garbett, ... Frontiers in Oncology 12, 835844, 2022 | 4 | 2022 |
Phase I trial of the MEK inhibitor selumetinib in combination with thoracic radiotherapy in non-small cell lung cancer K Haslett, P Koh, A Hudson, WD Ryder, S Falk, D Mullan, B Taylor, ... Clinical and translational radiation oncology 28, 24-31, 2021 | 4 | 2021 |
Protein kinase C loss-of-function mutations in cancer reveal role as tumor suppressor CE Antal, AM Hudson, E Kang, C Zanca, C Wirth, NL Stephenson, ... Cancer Research 75 (15_Supplement), 125-125, 2015 | 2 | 2015 |
Phase 1/2a study of AZD5305, a novel poly (adenosine diphosphate ribose) polymerase (PARP) 1-selective inhibitor in combination with new hormonal agents (NHAs) in patients (pts … A Azad, M Voskoboynik, AF Palma dos Reis, AM Joshua, AJ Weickhardt, ... Journal of Clinical Oncology 41 (6_suppl), TPS296-TPS296, 2023 | 1 | 2023 |
P16 status is an independent predictor of overall survival in metastatic penile cancer in a large contemporary cohort J Churchill, A Sachdeva, C Jones, A Issa, C Fankhauser, AM Hudson, ... | 1 | 2023 |