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Douglas Cavener
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The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor ζ-chain and induce a regulatory phenotype in naive T cells
F Fallarino, U Grohmann, S You, BC McGrath, DR Cavener, C Vacca, ...
The Journal of Immunology 176 (11), 6752-6761, 2006
12652006
Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates
DR Cavener
Nucleic acids research 15 (4), 1353-1361, 1987
11751987
Eukaryotic start and stop translation sites
DR Cavener, SC Ray
Nucleic acids research 19 (12), 3185-3192, 1991
7231991
The PERK eukaryotic initiation factor 2α kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas
P Zhang, B McGrath, A Frank, F Zambito, J Reinert, M Gannon, K Ma, ...
Molecular and cellular biology, 2002
7102002
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response
HY Jiang, SA Wek, BC McGrath, D Lu, T Hai, HP Harding, X Wang, D Ron, ...
Molecular and cellular biology 24 (3), 1365-1377, 2004
6052004
Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
T Ma, MA Trinh, AJ Wexler, C Bourbon, E Gatti, P Pierre, DR Cavener, ...
Nature neuroscience 16 (9), 1299-1305, 2013
5662013
The GCN2 eIF2α kinase is required for adaptation to amino acid deprivation in mice
P Zhang, BC McGrath, J Reinert, DAS Olsen, L Lei, S Gill, SA Wek, ...
Molecular and cellular biology 22 (19), 6681-6688, 2002
5392002
Phosphorylation of the α subunit of eukaryotic initiation factor 2 is required for activation of NF-κB in response to diverse cellular stresses
HY Jiang, SA Wek, BC McGrath, D Scheuner, RJ Kaufman, DR Cavener, ...
Molecular and cellular biology 23 (16), 5651-5663, 2003
5222003
Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism
V Senée, C Chelala, S Duchatelet, D Feng, H Blanc, JC Cossec, ...
Nature genetics 38 (6), 682-687, 2006
4012006
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex
S Hao, JW Sharp, CM Ross-Inta, BJ McDaniel, TG Anthony, RC Wek, ...
Science 307 (5716), 1776-1778, 2005
3812005
A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2α
R Sood, AC Porter, DA Olsen, DR Cavener, RC Wek
Genetics 154 (2), 787-801, 2000
3602000
PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage
E Bobrovnikova-Marjon, C Grigoriadou, D Pytel, F Zhang, J Ye, ...
Oncogene 29 (27), 3881-3895, 2010
3552010
Translational control and the unfolded protein response
RC Wek, DR Cavener
Antioxidants & redox signaling 9 (12), 2357-2372, 2007
3552007
GMC oxidoreductases: a newly defined family of homologous proteins with diverse catalytic activities
DR Cavener
Journal of molecular biology 223 (3), 811-814, 1992
3541992
PERK EIF2AK3 control of pancreatic β cell differentiation and proliferation is required for postnatal glucose homeostasis
W Zhang, D Feng, Y Li, K Iida, B McGrath, DR Cavener
Cell metabolism 4 (6), 491-497, 2006
3392006
Analysis of the PvuII Restriction Fragment-length Polymorphism and Exon Structure of the Estrogen Receptor Gene in Breast Cancer and Peripheral Blood
L Yaich, WD Dupont, DR Cavener, FF Parl
Cancer research 52 (1), 77-83, 1992
3341992
The GCN2 eIF2α kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid
F Guo, DR Cavener
Cell metabolism 5 (2), 103-114, 2007
3292007
Endoplasmic reticulum stress response mediated by the PERK-eIF2α-ATF4 pathway is involved in osteoblast differentiation induced by BMP2
A Saito, K Ochiai, S Kondo, K Tsumagari, T Murakami, DR Cavener, ...
Journal of biological chemistry 286 (6), 4809-4818, 2011
3102011
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation
E Bobrovnikova-Marjon, G Hatzivassiliou, C Grigoriadou, M Romero, ...
Proceedings of the National Academy of Sciences 105 (42), 16314-16319, 2008
2792008
Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2
TG Anthony, BJ McDaniel, RL Byerley, BC McGrath, DR Cavener, ...
Journal of Biological Chemistry 279 (35), 36553-36561, 2004
2642004
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