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Ariel Isaacs
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SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein
EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ...
Molecular psychiatry 28 (7), 2878-2893, 2023
752023
Preclinical development of a molecular clamp‐stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2
D Watterson, DK Wijesundara, N Modhiran, FL Mordant, Z Li, ...
Clinical & translational immunology 10 (4), e1269, 2021
542021
Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine
CLD McMillan, JJY Choo, A Idris, A Supramaniam, N Modhiran, ...
Science advances 7 (44), eabj8065, 2021
392021
A novel purification procedure for active recombinant human DPP4 and the inability of DPP4 to bind SARS-CoV-2
CR Xi, A Di Fazio, NA Nadvi, K Patel, MSW Xiang, HE Zhang, ...
Molecules 25 (22), 5392, 2020
322020
Bovine herpesvirus-4-vectored delivery of Nipah virus glycoproteins enhances T cell immunogenicity in pigs
M Pedrera, F Macchi, RK McLean, V Franceschi, N Thakur, L Russo, ...
Vaccines 8 (1), 115, 2020
302020
Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion
N Thakur, C Conceicao, A Isaacs, S Human, N Modhiran, RK McLean, ...
Journal of General Virology 102 (1), 001506, 2021
242021
Adjuvant selection for influenza and RSV prefusion subunit vaccines
A Isaacs, Z Li, STM Cheung, DK Wijesundara, CLD McMillan, N Modhiran, ...
Vaccines 9 (2), 71, 2021
152021
Molecular clamp stabilised Spike protein for protection against SARS-CoV-2
D Watterson, D Wijesundara, N Modhiran, F Mordant, Z Li, M Avumegah, ...
152020
Combinatorial FG immunogens as Nipah and respiratory syncytial virus vaccine candidates
A Isaacs, STM Cheung, N Thakur, N Jaberolansar, A Young, N Modhiran, ...
Viruses 13 (10), 1942, 2021
142021
Rapid response subunit vaccine design in the absence of structural information
DK Wijesundara, MS Avumegah, J Lackenby, N Modhiran, A Isaacs, ...
Frontiers in immunology 11, 592370, 2020
142020
Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants
A Isaacs, AA Amarilla, J Aguado, N Modhiran, EA Albornoz, AA Baradar, ...
Frontiers in Immunology 13, 926262, 2022
122022
A platform technology for generating subunit vaccines against diverse viral pathogens
A Young, A Isaacs, CAP Scott, N Modhiran, CLD McMillan, STM Cheung, ...
Frontiers in Immunology 13, 963023, 2022
112022
Monoclonal antibodies specific for SARS-CoV-2 spike protein suitable for multiple applications for current variants of concern
MS Morgan, K Yan, TT Le, RA Johnston, AA Amarilla, DA Muller, ...
Viruses 15 (1), 139, 2022
92022
Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology
J Aguado, AA Amarilla, A Taherian Fard, EA Albornoz, A Tyshkovskiy, ...
Nature Aging 3 (12), 1561-1575, 2023
72023
Structure and antigenicity of divergent Henipavirus fusion glycoproteins
A Isaacs, YS Low, KL Macauslane, J Seitanidou, CL Pegg, STM Cheung, ...
Nature communications 14 (1), 3577, 2023
72023
Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine
JS O’Donnell, A Isaacs, V Jakob, C Lebas, JB Barnes, PC Reading, ...
Frontiers in immunology 13, 976968, 2022
62022
Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concern
CLD McMillan, A Azuar, JJY Choo, N Modhiran, AA Amarilla, A Isaacs, ...
Vaccines 10 (4), 578, 2022
62022
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike-ACE2 receptor interaction
E Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ...
bioRxiv, 2022.01. 11.475947, 2022
52022
A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants
N Modhiran, SM Lauer, AA Amarilla, P Hewins, SIL van den Broek, ...
Iscience 26 (7), 107085, 2023
42023
Concerns regarding vaccination as a management strategy against koala retrovirus
BA Joyce, D Watterson, A Isaacs, KJ Chappell
bioRxiv, 2021.05. 10.443397, 2021
12021
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