Discrete LAT condensates encode antigen information from single pMHC: TCR binding events DB McAffee, MK O’Dair, JJ Lin, ST Low-Nam, KB Wilhelm, S Kim, S Morita, ... Nature communications 13 (1), 7446, 2022 | 18 | 2022 |
Membrane association transforms an inert anti-TCRβ Fab’ligand into a potent T cell receptor agonist JJ Lin, GP O’Donoghue, KB Wilhelm, MP Coyle, ST Low-Nam, NC Fay, ... Biophysical Journal 118 (12), 2879-2893, 2020 | 17 | 2020 |
Height, but not binding epitope, affects the potency of synthetic TCR agonists KB Wilhelm, S Morita, DB McAffee, S Kim, MK O'Dair, JT Groves Biophysical Journal 120 (18), 3869-3880, 2021 | 11 | 2021 |
The hydrogen-bonding dynamics of water to a nitrile-functionalized electrode is modulated by voltage according to ultrafast 2D IR spectroscopy MJ Ryan, N Yang, K Kwac, KB Wilhelm, BK Chi, DJ Weix, M Cho, ... Proceedings of the National Academy of Sciences 120 (52), e2314998120, 2023 | 2 | 2023 |
A Membrane‐Associated Light‐Harvesting Model is Enabled by Functionalized Assemblies of Gene‐Doubled TMV Proteins J Dai, KB Wilhelm, AJ Bischoff, JH Pereira, MT Dedeo, ... Small 19 (20), 2207805, 2023 | 2 | 2023 |
Allosteric inhibition of the T cell receptor by a designed membrane ligand Y Ye, S Morita, JJ Chang, PM Buckley, KB Wilhelm, D DiMaio, JT Groves, ... Elife 12, e82861, 2023 | 1 | 2023 |
T cell receptor inhibition with conditional transmembrane peptide Y Ye, S Morita, JJ Chang, PM Buckley, KB Wilhelm, D DiMaio, JT Groves, ... Biophysical Journal 123 (3), 510a, 2024 | | 2024 |
Synthetic T cell receptor ligands that mimic native pMHC ligand binding kinetics B Stinger, A Vissa, KB Wilhelm, JT Groves Biophysical Journal 123 (3), 102a, 2024 | | 2024 |
Differential Roles of Kinetic On-and Off-Rates in T-Cell Receptor Signal Integration Revealed with a Modified Fab′-DNA Ligand KB Wilhelm, A Vissa, JT Groves bioRxiv, 2024.04. 01.587588, 2024 | | 2024 |
Building an affinity panel of synthetic polyclonal T-cell receptor ligands that mimic native peptide-MHC A Vissa, KB Wilhelm, B Stinger, JT Groves Biophysical Journal 122 (3), 509a, 2023 | | 2023 |
The impact of Grb2 on phase condensation in live cells B Stinger, CW Lin, HT Phan, KB Wilhelm, A Vissa, JT Groves Biophysical Journal 122 (3), 159a, 2023 | | 2023 |
Mapping T-Cell Signal Integration From Synthetic, Membrane-Associated T-Cell Receptor Agonists KB Wilhelm UC Berkeley, 2022 | | 2022 |
Timing to Membrane-Associated Protein Condensation Controls Antigen Discrimination in T Cells MK O'Dair, D McAffee, KB Wilhelm, JT Groves Biophysical Journal 120 (3), 329a-330a, 2021 | | 2021 |
Differential Analysis of T-Cell Activation by a Library of Membrane-Tethered, Monovalent, Fab’-Based Synthetic T-Cell Receptor Agonists KB Wilhelm, S Morita, D McAffee, MK O'Dair, S Kim, JT Groves Biophysical Journal 120 (3), 330a, 2021 | | 2021 |
A Membrane-Activated, Universal T-Cell Receptor Agonist KB Wilhelm, MP Coyle, GP O'Donoghue, JJY Lin, ST Low-Nam, ... Biophysical Journal 116 (3), 530a-531a, 2019 | | 2019 |
Picking Up Good Vibes: Following Structural Dynamics of Fibril Aggregation with Two-Dimensional Infrared Spectroscopy KB Wilhelm, CA Olivares, IZ Han, A Ngamnithiporn, ME Wootton, ... | | 2015 |