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Kiera B. Wilhelm
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Discrete LAT condensates encode antigen information from single pMHC: TCR binding events
DB McAffee, MK O’Dair, JJ Lin, ST Low-Nam, KB Wilhelm, S Kim, S Morita, ...
Nature communications 13 (1), 7446, 2022
182022
Membrane association transforms an inert anti-TCRβ Fab’ligand into a potent T cell receptor agonist
JJ Lin, GP O’Donoghue, KB Wilhelm, MP Coyle, ST Low-Nam, NC Fay, ...
Biophysical Journal 118 (12), 2879-2893, 2020
172020
Height, but not binding epitope, affects the potency of synthetic TCR agonists
KB Wilhelm, S Morita, DB McAffee, S Kim, MK O'Dair, JT Groves
Biophysical Journal 120 (18), 3869-3880, 2021
112021
The hydrogen-bonding dynamics of water to a nitrile-functionalized electrode is modulated by voltage according to ultrafast 2D IR spectroscopy
MJ Ryan, N Yang, K Kwac, KB Wilhelm, BK Chi, DJ Weix, M Cho, ...
Proceedings of the National Academy of Sciences 120 (52), e2314998120, 2023
22023
A Membrane‐Associated Light‐Harvesting Model is Enabled by Functionalized Assemblies of Gene‐Doubled TMV Proteins
J Dai, KB Wilhelm, AJ Bischoff, JH Pereira, MT Dedeo, ...
Small 19 (20), 2207805, 2023
22023
Allosteric inhibition of the T cell receptor by a designed membrane ligand
Y Ye, S Morita, JJ Chang, PM Buckley, KB Wilhelm, D DiMaio, JT Groves, ...
Elife 12, e82861, 2023
12023
T cell receptor inhibition with conditional transmembrane peptide
Y Ye, S Morita, JJ Chang, PM Buckley, KB Wilhelm, D DiMaio, JT Groves, ...
Biophysical Journal 123 (3), 510a, 2024
2024
Synthetic T cell receptor ligands that mimic native pMHC ligand binding kinetics
B Stinger, A Vissa, KB Wilhelm, JT Groves
Biophysical Journal 123 (3), 102a, 2024
2024
Differential Roles of Kinetic On-and Off-Rates in T-Cell Receptor Signal Integration Revealed with a Modified Fab′-DNA Ligand
KB Wilhelm, A Vissa, JT Groves
bioRxiv, 2024.04. 01.587588, 2024
2024
Building an affinity panel of synthetic polyclonal T-cell receptor ligands that mimic native peptide-MHC
A Vissa, KB Wilhelm, B Stinger, JT Groves
Biophysical Journal 122 (3), 509a, 2023
2023
The impact of Grb2 on phase condensation in live cells
B Stinger, CW Lin, HT Phan, KB Wilhelm, A Vissa, JT Groves
Biophysical Journal 122 (3), 159a, 2023
2023
Mapping T-Cell Signal Integration From Synthetic, Membrane-Associated T-Cell Receptor Agonists
KB Wilhelm
UC Berkeley, 2022
2022
Timing to Membrane-Associated Protein Condensation Controls Antigen Discrimination in T Cells
MK O'Dair, D McAffee, KB Wilhelm, JT Groves
Biophysical Journal 120 (3), 329a-330a, 2021
2021
Differential Analysis of T-Cell Activation by a Library of Membrane-Tethered, Monovalent, Fab’-Based Synthetic T-Cell Receptor Agonists
KB Wilhelm, S Morita, D McAffee, MK O'Dair, S Kim, JT Groves
Biophysical Journal 120 (3), 330a, 2021
2021
A Membrane-Activated, Universal T-Cell Receptor Agonist
KB Wilhelm, MP Coyle, GP O'Donoghue, JJY Lin, ST Low-Nam, ...
Biophysical Journal 116 (3), 530a-531a, 2019
2019
Picking Up Good Vibes: Following Structural Dynamics of Fibril Aggregation with Two-Dimensional Infrared Spectroscopy
KB Wilhelm, CA Olivares, IZ Han, A Ngamnithiporn, ME Wootton, ...
2015
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Articles 1–16