A bacterial expression platform for production of therapeutic proteins containing human-like O-linked glycans T Du, N Buenbrazo, L Kell, S Rahmani, L Sim, SG Withers, S DeFrees, ... Cell chemical biology 26 (2), 203-212. e5, 2019 | 46 | 2019 |
Development and preclinical validation of a novel covalent ubiquitin receptor Rpn13 degrader in multiple myeloma Y Song, PMC Park, L Wu, A Ray, S Picaud, D Li, VK Wimalasena, T Du, ... Leukemia 33 (11), 2685-2694, 2019 | 44 | 2019 |
Genetic and structural validation of Aspergillus fumigatus UDP‐N‐acetylglucosamine pyrophosphorylase as an antifungal target W Fang, T Du, OG Raimi, R Hurtado‐Guerrero, MD Urbaniak, ... Molecular microbiology 89 (3), 479-493, 2013 | 40 | 2013 |
Transcriptome and Biochemical Analysis Reveals That Suppression of GPI-Anchor Synthesis Leads to Autophagy and Possible Necroptosis in Aspergillus fumigatus J Yan, T Du, W Zhao, T Hartmann, H Lu, Y Lü, H Ouyang, X Jiang, L Sun, ... PLoS One 8 (3), e59013, 2013 | 36 | 2013 |
Preclinical validation of Alpha-Enolase (ENO1) as a novel immunometabolic target in multiple myeloma A Ray, Y Song, T Du, D Chauhan, KC Anderson Oncogene 39 (13), 2786-2796, 2020 | 34 | 2020 |
Genetic and structural validation of Aspergillus fumigatus N-acetylphosphoglucosamine mutase as an antifungal target W Fang, T Du, OG Raimi, R Hurtado-Guerrero, K Mariño, AFM Ibrahim, ... Bioscience Reports 33 (5), e00063, 2013 | 30 | 2013 |
Targeting tryptophan catabolic kynurenine pathway enhances antitumor immunity and cytotoxicity in multiple myeloma A Ray, Y Song, T Du, YT Tai, D Chauhan, KC Anderson Leukemia 34 (2), 567-577, 2020 | 25 | 2020 |
Kexin-like endoprotease KexB is required for N-glycan processing, morphogenesis and virulence in Aspergillus fumigatus J Wang, H Zhou, H Lu, T Du, Y Luo, IBH Wilson, C Jin Fungal Genetics and Biology 76, 57-69, 2015 | 25 | 2015 |
Comparative proteomic analysis of an Aspergillus fumigatus mutant deficient in glucosidase I (AfCwh41) L Zhang, D Feng, W Fang, H Ouyang, Y Luo, T Du, C Jin Microbiology 155 (7), 2157-2167, 2009 | 25 | 2009 |
N-Glycosylation of Gel1 or Gel2 is vital for cell wall β-glucan synthesis in Aspergillus fumigatus W Zhao, Y Lü, H Ouyang, H Zhou, J Yan, T Du, C Jin Glycobiology 23 (8), 955-968, 2013 | 19 | 2013 |
Proteomic analysis identifies mechanism (s) of overcoming bortezomib resistance via targeting ubiquitin receptor Rpn13 T Du, Y Song, A Ray, D Chauhan, KC Anderson Leukemia 35 (2), 550-561, 2021 | 13 | 2021 |
Identification and validation of ecto-5'nucleotidase as an immunotherapeutic target in multiple myeloma A Ray, Y Song, T Du, L Buon, YT Tai, D Chauhan, KC Anderson Blood Cancer Journal 12 (4), 50, 2022 | 11 | 2022 |
Ubiquitin receptor PSMD4/Rpn10 is a novel therapeutic target in multiple myeloma T Du, Y Song, A Ray, X Wan, Y Yao, MK Samur, C Shen, J Penailillo, ... Blood, The Journal of the American Society of Hematology 141 (21), 2599-2614, 2023 | 10 | 2023 |
Identification of novel anti-tumor therapeutic target via proteomic characterization of ubiquitin receptor ADRM1/Rpn13 Y Song, T Du, A Ray, K Chauhan, M Samur, N Munshi, D Chauhan, ... Blood Cancer Journal 11 (1), 13, 2021 | 9 | 2021 |
Aspergillus fumigatus Mnn9 is responsible for mannan synthesis and required for covalent linkage of mannoprotein to the cell wall T Du, H Ouyang, J Voglmeir, IBH Wilson, C Jin Fungal genetics and biology 128, 20-28, 2019 | 8 | 2019 |
Aspergillus fumigatus phosphoethanolamine transferase gene gpi7 is required for proper transportation of the cell wall GPI-anchored proteins and polarized growth H Ouyang, T Du, H Zhou, IBH Wilson, J Yang, JP Latgé, C Jin Scientific Reports 9 (1), 5857, 2019 | 6 | 2019 |
Targeting ubiquitin-specific protease-7 in plasmacytoid dendritic cells triggers anti-myeloma immunity A Ray, T Du, Y Song, SJ Buhrlage, D Chauhan, KC Anderson Leukemia 35 (8), 2435-2438, 2021 | 3 | 2021 |
CD73 inhibition reverses immunosuppression and has potential As an immunomodulatory therapy in patients with multiple myeloma MR Junttila, A Ray, R Warne, XR Chen, T Du, F Lui, S Katewa, B Blank, ... Blood 140 (Supplement 1), 9957-9958, 2022 | 2 | 2022 |
ORIC-533, a small molecule CD73 inhibitor with best-in-class properties, reversesimmunosuppression and has potential as an immunomodulatory therapy in patients with multiple … MR Junttila, A Ray, R Warne, X Chen, T Du, D Sutimantanapi, JH Chang, ... Cancer Research 82 (12_Supplement), 2074-2074, 2022 | 2 | 2022 |
Ubiquitin receptor PSMD4/Rpn10 is a novel therapeutic target in myeloma DU Ting, Y Song, A Ray, RD Carrasco, S Dhe-Paganon, D Chauhan, ... Blood 138, 1591, 2021 | 2 | 2021 |