Nuclear protein-only ribonuclease P2 structure and biochemical characterization provide insight into the conserved properties of tRNA 5′ end processing enzymes A Karasik, A Shanmuganathan, MJ Howard, CA Fierke, M Koutmos Journal of molecular biology 428 (1), 26-40, 2016 | 41 | 2016 |
Loss of the mitochondrial protein-only ribonuclease P complex causes aberrant tRNA processing and lethality in Drosophila A Sen, A Karasik, A Shanmuganathan, E Mirkovic, M Koutmos, RT Cox Nucleic Acids Research 44 (13), 6409-6422, 2016 | 35 | 2016 |
Differential substrate recognition by isozymes of plant protein-only Ribonuclease P MJ Howard, A Karasik, BP Klemm, C Mei, A Shanmuganathan, CA Fierke, ... Rna 22 (5), 782-792, 2016 | 32 | 2016 |
Antivitamin B12 Inhibition of the Human B12‐Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate M Ruetz, A Shanmuganathan, C Gherasim, A Karasik, R Salchner, ... Angewandte Chemie International Edition 56 (26), 7387-7392, 2017 | 30 | 2017 |
Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P BP Klemm, A Karasik, KJ Kaitany, A Shanmuganathan, MJ Henley, ... Rna 23 (12), 1860-1873, 2017 | 22 | 2017 |
Interplay between substrate recognition, 5′ end tRNA processing and methylation activity of human mitochondrial RNase P A Karasik, CA Fierke, M Koutmos RNA 25 (12), 1646-1660, 2019 | 21 | 2019 |
Activation of the antiviral factor RNase L triggers translation of non-coding mRNA sequences A Karasik, GD Jones, AV DePass, NR Guydosh Nucleic Acids Research 49 (11), 6007-6026, 2021 | 12 | 2021 |
Disease-associated mutations in mitochondrial precursor tRNAs affect binding, m1R9 methylation, and tRNA processing by mtRNase P A Karasik, CA Wilhelm, CA Fierke, M Koutmos RNA 27 (4), 420-432, 2021 | 10 | 2021 |
Gambogic acid and juglone inhibit RNase P through distinct mechanisms NW Meyers, A Karasik, K Kaitany, CA Fierke, M Koutmos Journal of Biological Chemistry 298 (12), 2022 | 5 | 2022 |
In vitro transport of methotrexate by Drosophila Multidrug Resistance-associated Protein A Karasik, A Váradi, F Szeri Plos one 13 (10), e0205657, 2018 | 5 | 2018 |
Inhibierung des humanen B12‐verarbeitenden Enzyms CblC durch Antivitamine B12–Kristallstruktur des inaktiven ternären Komplexes mit dem Kosubstrat Glutathion M Ruetz, A Shanmuganathan, C Gherasim, A Karasik, R Salchner, ... Angewandte Chemie 129 (26), 7493-7498, 2017 | 5 | 2017 |
Boosted coupling of ATP hydrolysis to substrate transport upon cooperative estradiol-17-β-D-glucuronide binding in a Drosophila ATP binding cassette type-C transporter A Karasik, KV Ledwitch, T Arányi, A Váradi, A Roberts, F Szeri The FASEB Journal 32 (2), 669, 2018 | 3 | 2018 |
Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response A Karasik, HA Lorenzi, AV DePass, NR Guydosh bioRxiv, 2023 | | 2023 |
Mode of inhibition of RNase P by gambogic acid and juglone NW Meyers, A Karasik, K Kaitany, CA Fierke, M Koutmos bioRxiv, 2022.10. 20.512141, 2022 | | 2022 |
Precursor TRNA Processing By Protein Only RNASE PS And Its Connection To Mitochondrial Diseases A Karasik, ... Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, 2018 | | 2018 |