The translational benefits of sheep as large animal models of human neurological disorders SJ Murray, NL Mitchell Frontiers in Veterinary Science 9, 831838, 2022 | 26 | 2022 |
Intravitreal gene therapy protects against retinal dysfunction and degeneration in sheep with CLN5 Batten disease SJ Murray, KN Russell, TR Melzer, SJ Gray, SJ Heap, DN Palmer, ... Experimental Eye Research 207, 108600, 2021 | 26 | 2021 |
Chemical neuroanatomy of the substantia nigra in the ovine brain SJ Murray, BL Black, SJ Reid, SR Rudiger, CS Bawden, RG Snell, ... Journal of chemical neuroanatomy 97, 43-56, 2019 | 16 | 2019 |
Natural history of retinal degeneration in ovine models of CLN5 and CLN6 neuronal ceroid lipofuscinoses SJ Murray, NL Mitchell Scientific Reports 12 (1), 3670, 2022 | 6 | 2022 |
Progressive MRI brain volume changes in ovine models of CLN5 and CLN6 neuronal ceroid lipofuscinosis SJ Murray, MM Almuqbel, SA Felton, NJ Palmer, DJ Myall, R Shoorangiz, ... Brain Communications 5 (1), fcac339, 2023 | 3 | 2023 |
Intravitreal injections in the ovine eye SJ Murray, NL Mitchell JoVE (Journal of Visualized Experiments), e63823, 2022 | 3 | 2022 |
Aggregation chimeras provide evidence of in vivo intercellular correction in ovine CLN6 neuronal ceroid lipofuscinosis (Batten disease) LA Barry, GW Kay, NL Mitchell, SJ Murray, NP Jay, DN Palmer Plos one 17 (4), e0261544, 2022 | 3 | 2022 |
Intraparenchymal convection enhanced delivery of AAV in sheep to treat Mucopolysaccharidosis IIIC C O’Leary, G Forte, NL Mitchell, AS Youshani, A Dyer, MP Wellby, ... Journal of Translational Medicine 21 (1), 437, 2023 | 2 | 2023 |
Ocular therapies for neuronal ceroid lipofuscinoses: more than meets the eye SJ Murray, NL Mitchell Neural Regeneration Research 17 (8), 1755-1756, 2022 | 2 | 2022 |
Efficacy of dual intracerebroventricular and intravitreal CLN5 gene therapy in sheep prompts the first clinical trial to treat CLN5 Batten disease SJ Murray, MP Wellby, GK Barrell, KN Russell, AR Deane, JR Wynyard, ... Frontiers in Pharmacology 14, 1212235, 2023 | 1 | 2023 |
Long-term safety and dose escalation of intracerebroventricular CLN5 gene therapy in sheep supports clinical translation for CLN5 Batten disease NL Mitchell, SJ Murray, MP Wellby, GK Barrell, KN Russell, AR Deane, ... Frontiers in Genetics 14, 1212228, 2023 | 1 | 2023 |
BRAIN COMMUNICATIONS SJ Murray, MM Almuqbel, SA Felton, NJ Palmer, DJ Myall, R Shoorangiz, ... | | 2023 |
A novel Adeno-associated viral gene therapy treatment protocol in sheep for use in MPSIIIC and other neurological disorders C O'Leary, G Forte, NL Mitchell, AS Youshani, A Dyer, M Wellby, ... Human Gene Therapy 33 (23-24), A76-A77, 2022 | | 2022 |
Breed specific ovine brain MRI tissue probability maps SJ Murray, TR Melzer OSF, 2022 | | 2022 |
Efficacy of gene therapy in a CLN5 sheep model using a dual route of administration supports a first-in-human clinical trial L Jacobsen, J Daily, S Murray, D Palmer, N Mitchell, E Beausoleil, ... Elsevier, 2022 | | 2022 |
Efficacy of Gene Therapy in a CLN5 Sheep Model Using a Dual Route of Administration J Daily, S Murray, D Palmer, N Mitchell ANNALS OF NEUROLOGY 90, S85-S85, 2021 | | 2021 |
AAV Gene Transfer Halts Disease Progression in Sheep with CLN5 Batten Disease after Pre-Or Post-Symptomatic Administration NL Mitchell, SJ Murray, KN Russell, MP Wellby, GK Barrell, SJ Gray, ... MOLECULAR THERAPY 27 (4), 423-423, 2019 | | 2019 |
Characterisation of the anatomy and neurochemistry of the basal ganglia in a transgenic sheep model of Huntington's disease S Murray PhD Thesis-University of Auckland, 2017 | | 2017 |
Was verursacht Multiple Sklerose? M Paulig Nervenheilkunde 29 (12), 820-824, 2010 | | 2010 |
Supplementary Material Long-term safety and dose escalation of intracerebroventricular CLN5 gene therapy in sheep supports clinical translation for CLN5 Batten NL Mitchell, SJ Murray, MP Wellby, GK Barrell, KN Russell, AR Deane, ... | | |