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Samantha J Murray
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The translational benefits of sheep as large animal models of human neurological disorders
SJ Murray, NL Mitchell
Frontiers in Veterinary Science 9, 831838, 2022
262022
Intravitreal gene therapy protects against retinal dysfunction and degeneration in sheep with CLN5 Batten disease
SJ Murray, KN Russell, TR Melzer, SJ Gray, SJ Heap, DN Palmer, ...
Experimental Eye Research 207, 108600, 2021
262021
Chemical neuroanatomy of the substantia nigra in the ovine brain
SJ Murray, BL Black, SJ Reid, SR Rudiger, CS Bawden, RG Snell, ...
Journal of chemical neuroanatomy 97, 43-56, 2019
162019
Natural history of retinal degeneration in ovine models of CLN5 and CLN6 neuronal ceroid lipofuscinoses
SJ Murray, NL Mitchell
Scientific Reports 12 (1), 3670, 2022
62022
Progressive MRI brain volume changes in ovine models of CLN5 and CLN6 neuronal ceroid lipofuscinosis
SJ Murray, MM Almuqbel, SA Felton, NJ Palmer, DJ Myall, R Shoorangiz, ...
Brain Communications 5 (1), fcac339, 2023
32023
Intravitreal injections in the ovine eye
SJ Murray, NL Mitchell
JoVE (Journal of Visualized Experiments), e63823, 2022
32022
Aggregation chimeras provide evidence of in vivo intercellular correction in ovine CLN6 neuronal ceroid lipofuscinosis (Batten disease)
LA Barry, GW Kay, NL Mitchell, SJ Murray, NP Jay, DN Palmer
Plos one 17 (4), e0261544, 2022
32022
Intraparenchymal convection enhanced delivery of AAV in sheep to treat Mucopolysaccharidosis IIIC
C O’Leary, G Forte, NL Mitchell, AS Youshani, A Dyer, MP Wellby, ...
Journal of Translational Medicine 21 (1), 437, 2023
22023
Ocular therapies for neuronal ceroid lipofuscinoses: more than meets the eye
SJ Murray, NL Mitchell
Neural Regeneration Research 17 (8), 1755-1756, 2022
22022
Efficacy of dual intracerebroventricular and intravitreal CLN5 gene therapy in sheep prompts the first clinical trial to treat CLN5 Batten disease
SJ Murray, MP Wellby, GK Barrell, KN Russell, AR Deane, JR Wynyard, ...
Frontiers in Pharmacology 14, 1212235, 2023
12023
Long-term safety and dose escalation of intracerebroventricular CLN5 gene therapy in sheep supports clinical translation for CLN5 Batten disease
NL Mitchell, SJ Murray, MP Wellby, GK Barrell, KN Russell, AR Deane, ...
Frontiers in Genetics 14, 1212228, 2023
12023
BRAIN COMMUNICATIONS
SJ Murray, MM Almuqbel, SA Felton, NJ Palmer, DJ Myall, R Shoorangiz, ...
2023
A novel Adeno-associated viral gene therapy treatment protocol in sheep for use in MPSIIIC and other neurological disorders
C O'Leary, G Forte, NL Mitchell, AS Youshani, A Dyer, M Wellby, ...
Human Gene Therapy 33 (23-24), A76-A77, 2022
2022
Breed specific ovine brain MRI tissue probability maps
SJ Murray, TR Melzer
OSF, 2022
2022
Efficacy of gene therapy in a CLN5 sheep model using a dual route of administration supports a first-in-human clinical trial
L Jacobsen, J Daily, S Murray, D Palmer, N Mitchell, E Beausoleil, ...
Elsevier, 2022
2022
Efficacy of Gene Therapy in a CLN5 Sheep Model Using a Dual Route of Administration
J Daily, S Murray, D Palmer, N Mitchell
ANNALS OF NEUROLOGY 90, S85-S85, 2021
2021
AAV Gene Transfer Halts Disease Progression in Sheep with CLN5 Batten Disease after Pre-Or Post-Symptomatic Administration
NL Mitchell, SJ Murray, KN Russell, MP Wellby, GK Barrell, SJ Gray, ...
MOLECULAR THERAPY 27 (4), 423-423, 2019
2019
Characterisation of the anatomy and neurochemistry of the basal ganglia in a transgenic sheep model of Huntington's disease
S Murray
PhD Thesis-University of Auckland, 2017
2017
Was verursacht Multiple Sklerose?
M Paulig
Nervenheilkunde 29 (12), 820-824, 2010
2010
Supplementary Material Long-term safety and dose escalation of intracerebroventricular CLN5 gene therapy in sheep supports clinical translation for CLN5 Batten
NL Mitchell, SJ Murray, MP Wellby, GK Barrell, KN Russell, AR Deane, ...
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