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Claire Steppan
Claire Steppan
Verified email at pfizer.com
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Cited by
Year
The hormone resistin links obesity to diabetes
CM Steppan, ST Bailey, S Bhat, EJ Brown, RR Banerjee, CM Wright, ...
Nature 409 (6818), 307-312, 2001
73292001
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19
DR Owen, CMN Allerton, AS Anderson, L Aschenbrenner, M Avery, ...
Science 374 (6575), 1586-1593, 2021
12702021
A family of tissue-specific resistin-like molecules
CM Steppan, EJ Brown, CM Wright, S Bhat, RR Banerjee, CY Dai, ...
Proceedings of the National Academy of Sciences 98 (2), 502-506, 2001
10552001
Regulation of fasted blood glucose by resistin
RR Banerjee, SM Rangwala, JS Shapiro, AS Rich, B Rhoades, Y Qi, ...
Science 303 (5661), 1195-1198, 2004
10372004
Resistin and obesity-associated insulin resistance
CM Steppan, MA Lazar
Trends in endocrinology & Metabolism 13 (1), 18-23, 2002
9002002
Leptin is a potent stimulator of bone growth in ob/ob mice
CM Steppan, DT Crawford, KL Chidsey-Frink, HZ Ke, AG Swick
Regulatory peptides 92 (1-3), 73-78, 2000
6942000
The current biology of resistin
CM Steppan, MA Lazar
Journal of internal medicine 255 (4), 439-447, 2004
5832004
A futile metabolic cycle activated in adipocytes by antidiabetic agents
HP Guan, Y Li, MV Jensen, CB Newgard, CM Steppan, MA Lazar
Nature medicine 8 (10), 1122-1128, 2002
4782002
Activation of SOCS-3 by resistin
CM Steppan, J Wang, EL Whiteman, MJ Birnbaum, MA Lazar
Molecular and cellular biology 25 (4), 1569-1575, 2005
4442005
Discovery of ketone-based covalent inhibitors of coronavirus 3CL proteases for the potential therapeutic treatment of COVID-19
RL Hoffman, RS Kania, MA Brothers, JF Davies, RA Ferre, KS Gajiwala, ...
Journal of medicinal chemistry 63 (21), 12725-12747, 2020
4082020
Abdominal fat distribution in pre-and postmenopausal women: the impact of physical activity, age, and menopausal status
JA Kanaley, C Sames, L Swisher, AG Swick, LL Ploutz-Snyder, ...
Metabolism-Clinical and Experimental 50 (8), 976-982, 2001
2152001
A role for leptin in brain development
CM Steppan, AG Swick
Biochemical and biophysical research communications 256 (3), 600-602, 1999
2151999
Altered expression of C/EBP family members results in decreased adipogenesis with aging
I Karagiannides, T Tchkonia, DE Dobson, CM Steppan, P Cummins, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2001
2052001
Developing predictive assays: the phenotypic screening “rule of 3”
F Vincent, P Loria, M Pregel, R Stanton, L Kitching, K Nocka, R Doyonnas, ...
Science translational medicine 7 (293), 293ps15-293ps15, 2015
2022015
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
B Boras, RM Jones, BJ Anson, D Arenson, L Aschenbrenner, ...
Nature communications 12 (1), 6055, 2021
1962021
Bacterial colonization leads to the colonic secretion of RELMβ/FIZZ2, a novel goblet cell-specific protein
W He, ML Wang, HQ Jiang, CM Steppan, ME Shin, MC Thurnheer, ...
Gastroenterology 125 (5), 1388-1397, 2003
1832003
Discovery of a clinical candidate from the structurally unique dioxa-bicyclo [3.2. 1] octane class of sodium-dependent glucose cotransporter 2 inhibitors
V Mascitti, TS Maurer, RP Robinson, J Bian, CM Boustany-Kari, T Brandt, ...
Journal of medicinal chemistry 54 (8), 2952-2960, 2011
1292011
Mouse and human resistins impair glucose transport in primary mouse cardiomyocytes, and oligomerization is required for this biological action
C Graveleau, VG Zaha, A Mohajer, RR Banerjee, N Dudley-Rucker, ...
Journal of biological chemistry 280 (36), 31679-31685, 2005
1262005
Variation in resistin gene promoter not associated with polycystic ovary syndrome
M Urbanek, Y Du, K Silander, FS Collins, CM Steppan, JF Strauss III, ...
Diabetes 52 (1), 214-217, 2003
1252003
A Comparative Analysis of SARS-CoV-2 Antivirals Characterizes 3CLpro Inhibitor PF-00835231 as a Potential New Treatment for COVID-19
M de Vries, AS Mohamed, RA Prescott, AM Valero-Jimenez, L Desvignes, ...
Journal of Virology 95 (10), 10.1128/jvi. 01819-20, 2021
1192021
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