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Gyula Pálfy
Gyula Pálfy
Verified email at phys.chem.ethz.ch
Title
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Cited by
Year
Structural impact of GTP binding on downstream KRAS signaling
DK Menyhárd, G Pálfy, Z Orgován, I Vida, GM Keserű, A Perczel
Chemical science 11 (34), 9272-9289, 2020
342020
1H, 15N backbone assignment and comparative analysis of the wild type and G12C, G12D, G12V mutants of K-Ras bound to GDP at physiological pH
G Pálfy, I Vida, A Perczel
Biomolecular NMR Assignments 14 (1), 1-7, 2020
332020
Ezrin interacts with S100A4 via both its N-and C-terminal domains
B Biri-Kovács, B Kiss, H Vadászi, G Gógl, G Pálfy, G Török, L Homolya, ...
PloS one 12 (5), e0177489, 2017
242017
Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery
G Pálfy, DK Menyhárd, A Perczel
Cancer and Metastasis Reviews 39 (4), 1075-1089, 2020
202020
DUckCov: a Dynamic Undocking‐Based Virtual Screening Protocol for Covalent Binders
M Rachman, A Scarpino, D Bajusz, G Pálfy, I Vida, A Perczel, X Barril, ...
ChemMedChem 14 (10), 1011-1021, 2019
192019
Multiple S100 protein isoforms and C-terminal phosphorylation contribute to the paralog-selective regulation of nonmuscle myosin 2 filaments
P Ecsédi, N Billington, G Pálfy, G Gógl, B Kiss, É Bulyáki, A Bodor, ...
Journal of Biological Chemistry 293 (38), 14850-14867, 2018
182018
Multilevel Changes in Protein Dynamics upon Complex Formation of the Calcium‐Loaded S100A4 with a Nonmuscle Myosin IIA Tail Fragment
G Pálfy, B Kiss, L Nyitray, A Bodor
ChemBioChem 17 (19), 1829-1838, 2016
182016
Assessment of tractable cysteines for covalent targeting by screening covalent fragments
L Petri, P Ábrányi‐Balogh, I Tímea, G Pálfy, A Perczel, D Knez, M Hrast, ...
ChemBioChem 22 (4), 743-753, 2021
172021
Tumor‐Suppressor p53TAD1–60 Forms a Fuzzy Complex with Metastasis‐Associated S100A4: Structural Insights and Dynamics by an NMR/MD Approach
EF Dudás, G Pálfy, DK Menyhárd, F Sebák, P Ecsédi, L Nyitray, A Bodor
ChemBioChem 21 (21), 3087-3095, 2020
172020
The Importance of Mg2+‐Free State in Nucleotide Exchange of Oncogenic K‐Ras Mutants
G Pálfy, DK Menyhárd, H Ákontz‐Kiss, I Vida, G Batta, O Tőke, A Perczel
Chemistry–A European Journal 28 (59), e202201449, 2022
92022
Investigating thermal stability based on the structural changes of lactase enzyme by several orthogonal methods
M Király, BD Kiss, P Horváth, L Drahos, A Mirzahosseini, G Pálfy, I Antal, ...
Biotechnology Reports 30, e00637, 2021
52021
Bacterial fermentation and isotope labelling optimized for amyloidogenic proteins
I Vida, Z Fazekas, G Gyulai, D Nagy‐Fazekas, G Pálfy, P Stráner, E Kiss, ...
Microbial Biotechnology 14 (3), 1107-1119, 2021
32021
Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency
Z Orgován, N Péczka, L Petri, P Ábrányi-Balogh, I Ranđelović, S Tóth, ...
European Journal of Medicinal Chemistry 250, 115212, 2023
22023
NMR-Chemical-Shift-Driven Protocol Reveals the Cofactor-Bound, Complete Structure of Dynamic Intermediates of the Catalytic Cycle of Oncogenic KRAS G12C Protein and the …
M Gadanecz, Z Fazekas, G Pálfy, D Karancsiné Menyhárd, A Perczel
International Journal of Molecular Sciences 24 (15), 12101, 2023
12023
Assessment of tractable cysteines by covalent fragments screening
L Petri, P Abranyi-Balogh, T Imre, G Pálfy, A Perczel, D Knez, M Hrast, ...
ChemBioChem 10, 2020
12020
Mapping protein binding sites by photoreactive fragment pharmacophores
G Keseru, P Ábrányi-Balogh, D Bajusz, Z Orgovan, A Keeley, L Petri, ...
2023
Investigating the Influence of Heat Stress to the Activity And Structural Changes of Lactase Enzyme
M Király, BD Kiss, P Horváth, L Drahos, A Mirzahosseini, G Pálfy, I Antal, ...
Acta Pharmaceutica Hungarica 91 (3-4), 251-252, 2021
2021
Front Cover: Tumor‐Suppressor p53TAD1–60 Forms a Fuzzy Complex with Metastasis‐Associated S100A4: Structural Insights and Dynamics by an NMR/MD …
EF Dudás, G Pálfy, DK Menyhárd, F Sebák, P Ecsédi, L Nyitray, A Bodor
ChemBioChem 21 (21), 2997-2997, 2020
2020
Allele-specific inhibitors of mutant KRAS are in the focus of RASopathy consortium
K Nyíri, G Koppány, G Pálfy, I Vida, S Tóth, Z Orgován, I Ranđelović, ...
Magyar Onkologia 63 (4), 310-323, 2019
2019
Front Cover: DUckCov: a Dynamic Undocking‐Based Virtual Screening Protocol for Covalent Binders (ChemMedChem 10/2019)
M Rachman, A Scarpino, D Bajusz, G Pálfy, I Vida, A Perczel, X Barril, ...
ChemMedChem 14 (10), 994-994, 2019
2019
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