Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy S Da Mesquita, Z Papadopoulos, T Dykstra, L Brase, FG Farias, M Wall, ... Nature 593 (7858), 255-260, 2021 | 207 | 2021 |
The Gossypium longicalyx Genome as a Resource for Cotton Breeding and Evolution CE Grover, M Pan, D Yuan, MA Arick, G Hu, L Brase, DM Stelly, Z Lu, ... G3: Genes, Genomes, Genetics 10 (5), 1457-1467, 2020 | 39 | 2020 |
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4 M Gratuze, JCM Schlachetzki, RDO Albanus, N Jain, B Novotny, L Brase, ... Neuron 111 (2), 202-219. e7, 2023 | 35 | 2023 |
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers L Brase, SF You, R D’Oliveira Albanus, JL Del-Aguila, Y Dai, BC Novotny, ... Nature communications 14 (1), 2314, 2023 | 22 | 2023 |
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology PW Sheehan, CJ Nadarajah, MF Kanan, JN Patterson, B Novotny, ... Neuron 111 (15), 2383-2398. e7, 2023 | 19 | 2023 |
ExtRamp: a novel algorithm for extracting the ramp sequence based on the tRNA adaptation index or relative codon adaptiveness JB Miller, LR Brase, PG Ridge Nucleic Acids Research 47 (3), 1123-1131, 2019 | 16 | 2019 |
A landscape of the genetic and cellular heterogeneity in Alzheimer disease L Brase, SF You, RDO Albanus, JL Del-Aguila, Y Dai, BC Novotny, ... Medrxiv, 2021.11. 30.21267072, 2021 | 11 | 2021 |
MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state SF You, L Brase, F Filipello, AK Iyer, J Del-Aguila, J He, RDO Albanus, ... medRxiv, 2023 | 4 | 2023 |
Meningeal lymphatics modulate microglial activation and immunotherapy in Alzheimer’s disease S Da Mesquita, Z Papadopoulos, T Dykstra, L Brase, FG Farias, M Wall, ... Nature 593 (7858), 255, 2021 | 3 | 2021 |
Dominantly Inherited Alzheimer N, Benitez BA, Karch CM, Perrin RJ, Farlow M, Chhatwal JP, Holtzman DM, Cruchaga C, Harari O, Kipnis J. Meningeal lymphatics affect microglia … S Da Mesquita, Z Papadopoulos, T Dykstra, L Brase, FG Farias, M Wall, ... Nature 593 (7858), 255-260, 2021 | 3 | 2021 |
LMNA‐mediated nucleoskeleton dysregulation in Alzheimer disease MJ Rosene, N Wen, Z Li, L Brase, S Hsu, C Cruchaga, S Temple, O Harari, ... Alzheimer's & Dementia 17, e054396, 2021 | 2 | 2021 |
Systematic analysis of cellular crosstalk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer’s disease RD Albanus, GM Finan, L Brase, S Chen, Q Guo, A Kannan, M Acquarone, ... | 1 | 2022 |
Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease AM Eteleeb, BC Novotny, CS Tarraga, C Sohn, E Dhungel, L Brase, ... PLoS biology 22 (4), e3002607, 2024 | | 2024 |
Comparative gene regulatory networks modulating APOE expression in microglia and astrocytes L Brase, Y Yu, E McDade, ... medRxiv, 2024.04. 19.24306098, 2024 | | 2024 |
Cross‐omics integration analysis revels synaptic dysregulation across brain regions at later stages of Alzheimer disease AM Eteleeb, BC Novotny, C Soriano‐Tarraga, C Sohn, E Dhungel, ... Alzheimer's & Dementia 19, e077100, 2023 | | 2023 |
Microglia transcriptional heterogeneity across human and experimental models A Garg, BC Novotny, R D'Oliveira Albanus, L Brase, CM Karch, JC Morris, ... Alzheimer's & Dementia 19, e076619, 2023 | | 2023 |
Ambient RNA from CSF to capture brain cell‐type signatures in AD and other neurodegenerative diseases J Kaczaral, J Buss, A Eteleeb, BC Novotny, R D'Oliveira Albanus, L Brase, ... Alzheimer's & Dementia 19, e077297, 2023 | | 2023 |
A cell‐autonomous role of DNAJC5 in microglial‐mediated proteostasis in Alzheimer’s disease MJ Rosene, NP Nykanen, L Brase, O Harari, BA Benitez Alzheimer's & Dementia 19, e071075, 2023 | | 2023 |
Phospholipase D3 drives microglial response to amyloid pathology in Alzheimer’s disease MJ Rosene, E Danhash, SF You, AK Iyer, S Hsu, MA de Sa Lopes, ... Alzheimer's & Dementia 19, e076884, 2023 | | 2023 |
Leveraging systems biology approaches and single‐nucleus RNA‐seq to study sex differences in AD L Brase, AR Dunn, JC Morris, RJ Perrin, L Dumitrescu, CC Kaczorowski, ... Alzheimer's & Dementia 19, e076877, 2023 | | 2023 |