| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13217* | 2021 |
| An innovative high-throughput screening approach for discovery of small molecules that inhibit TNF receptors CH Lo, N Vunnam, AK Lewis, TL Chiu, BE Brummel, TM Schaaf, BD Grant, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (8), 950-961, 2017 | 65 | 2017 |
| Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies CH Lo, CKW Lim, Z Ding, SP Wickramasinghe, AR Braun, KH Ashe, ... Alzheimer's & Dementia 15 (11), 1489-1502, 2019 | 58 | 2019 |
| Noncompetitive inhibitors of TNFR1 probe conformational activation states CH Lo, TM Schaaf, BD Grant, CKW Lim, P Bawaskar, CC Aldrich, ... Science signaling 12 (592), eaav5637, 2019 | 49 | 2019 |
| Toward precision phenotyping of multiple sclerosis D Pitt, CH Lo, SA Gauthier, RA Hickman, E Longbrake, LM Airas, ... Neurology: Neuroimmunology & Neuroinflammation 9 (6), e200025, 2022 | 36 | 2022 |
| Dimethyl fumarate reduces inflammation in chronic active multiple sclerosis lesions N Zinger, G Ponath, E Sweeney, TD Nguyen, CH Lo, I Diaz, A Dimov, ... Neurology: Neuroimmunology & Neuroinflammation 9 (2), e1138, 2022 | 33 | 2022 |
| Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease J Zeng, R Acin-Perez, EA Assali, A Martin, AJ Brownstein, A Petcherski, ... Nature communications 14 (1), 2573, 2023 | 26 | 2023 |
| Discovery of small molecule inhibitors of huntingtin exon 1 aggregation by FRET-based high-throughput screening in living cells CH Lo, NK Pandey, CKW Lim, Z Ding, M Tao, DD Thomas, R Langen, ... ACS Chemical Neuroscience 11 (15), 2286-2295, 2020 | 26 | 2020 |
| Defective lysosomal acidification: a new prognostic marker and therapeutic target for neurodegenerative diseases CH Lo, J Zeng Translational Neurodegeneration 12 (1), 29, 2023 | 25 | 2023 |
| Conformational states of TNFR1 as a molecular switch for receptor function CH Lo, EC Huber, JN Sachs Protein Science 29 (6), 1401-1415, 2020 | 24 | 2020 |
| Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors AR Braun, EE Liao, M Horvath, P Kalra, K Acosta, MC Young, NN Kochen, ... npj Parkinson's Disease 7 (1), 52, 2021 | 23 | 2021 |
| Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration JD Quick, C Silva, JH Wong, KL Lim, R Reynolds, AM Barron, J Zeng, ... Journal of Neuroinflammation 20 (1), 185, 2023 | 22 | 2023 |
| Integrative multi-omics and systems bioinformatics in translational neuroscience: A data mining perspective LM O'Connor, BA O'Connor, SB Lim, J Zeng, CH Lo Journal of Pharmaceutical Analysis 13 (8), 836-850, 2023 | 19 | 2023 |
| Home-based care for people with Alzheimer’s disease and related dementias (ADRD) during COVID-19 pandemic: From challenges to solutions A Sm-Rahman, CH Lo, A Ramic, Y Jahan International journal of environmental research and public health 17 (24), 9303, 2020 | 18 | 2020 |
| Soluble extracellular domain of death receptor 5 inhibits TRAIL-induced apoptosis by disrupting receptor–receptor interactions N Vunnam, CH Lo, BD Grant, DD Thomas, JN Sachs Journal of Molecular Biology 429 (19), 2943-2953, 2017 | 18 | 2017 |
| Astrocyte heterogeneity in multiple sclerosis: current understanding and technical challenges CH Lo, M Skarica, M Mansoor, S Bhandarkar, S Toro, D Pitt Frontiers in Cellular Neuroscience 15, 726479, 2021 | 16 | 2021 |
| Fluorescence-based TNFR1 biosensor for monitoring receptor structural and conformational dynamics and discovery of small molecule modulators CH Lo, TM Schaaf, DD Thomas, JN Sachs The TNF Superfamily: Methods and Protocols, 121-137, 2021 | 16 | 2021 |
| Application of polymersomes in membrane protein study and drug discovery: Progress, strategies, and perspectives CH Lo, J Zeng Bioengineering & translational medicine 8 (1), e10350, 2023 | 14 | 2023 |
| The role of wild-type tau in Alzheimer’s disease and related tauopathies CH Lo, JN Sachs Journal of Life Sciences (Westlake Village, Calif.) 2 (4), 1, 2020 | 13 | 2020 |
| Recent advances in cellular biosensor technology to investigate tau oligomerization CH Lo Bioengineering & Translational Medicine 6 (3), e10231, 2021 | 12 | 2021 |
