Brian J. North
Brian J. North
Creighton University School of Medicine
Verified email at - Homepage
Cited by
Cited by
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
BJ North, BL Marshall, MT Borra, JM Denu, E Verdin
Molecular cell 11 (2), 437-444, 2003
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
NL Price, AP Gomes, AJY Ling, FV Duarte, A Martin-Montalvo, BJ North, ...
Cell metabolism 15 (5), 675-690, 2012
The intersection between aging and cardiovascular disease
BJ North, DA Sinclair
Circulation research 110 (8), 1097-1108, 2012
Sirtuins: Sir2-related NAD-dependent protein deacetylases
BJ North, E Verdin
Genome biology 5, 1-12, 2004
The human silent information regulator (Sir) 2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase
B Schwer, BJ North, RA Frye, M Ott, E Verdin
The Journal of cell biology 158 (4), 647-657, 2002
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase
N Ahuja, B Schwer, S Carobbio, D Waltregny, BJ North, V Castronovo, ...
Journal of Biological Chemistry 282 (46), 33583-33592, 2007
SIRT1 regulates HIV transcription via Tat deacetylation
S Pagans, A Pedal, BJ North, K Kaehlcke, BL Marshall, A Dorr, ...
PLoS biology 3 (2), e41, 2005
Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis
BJ North, E Verdin
PloS one 2 (8), e784, 2007
Selective Sirt2 inhibition by ligand-induced rearrangement of the active site
T Rumpf, M Schiedel, B Karaman, C Roessler, BJ North, A Lehotzky, ...
Nature communications 6 (1), 6263, 2015
Histone deacetylase HDAC8 associates with smooth muscle α‐actin and is essential for smooth muscle cell contractility
D Waltregny, W Glénisson, SL Tran, BJ North, E Verdin, A Colige, ...
The FASEB journal 19 (8), 966-968, 2005
SIRT 2 induces the checkpoint kinase BubR1 to increase lifespan
BJ North, MA Rosenberg, KB Jeganathan, AV Hafner, S Michan, J Dai, ...
The EMBO journal 33 (13), 1438-1453, 2014
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy
Y Gao, NT Nihira, X Bu, C Chu, J Zhang, A Kolodziejczyk, Y Fan, NT Chan, ...
Nature cell biology 22 (9), 1064-1075, 2020
Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation
BJ North, E Verdin
Journal of Biological Chemistry 282 (27), 19546-19555, 2007
Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues
D Waltregny, L De Leval, W Glénisson, SL Tran, BJ North, A Bellahcène, ...
The American journal of pathology 165 (2), 553-564, 2004
Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling
B Beirowski, J Gustin, SM Armour, H Yamamoto, A Viader, BJ North, ...
Proceedings of the National Academy of Sciences 108 (43), E952-E961, 2011
TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling
B Wang, Z Jie, D Joo, A Ordureau, P Liu, W Gan, J Guo, J Zhang, BJ North, ...
Nature 545 (7654), 365-369, 2017
The emerging roles of protein homeostasis‐governing pathways in Alzheimer's disease
J Cheng, BJ North, T Zhang, X Dai, K Tao, J Guo, W Wei
Aging cell 17 (5), e12801, 2018
Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells
D Waltregny, B North, F Van Mellaert, J de Leval, E Verdin, V Castronovo
European journal of histochemistry 48 (3), 273-290, 2004
Preparation of enzymatically active recombinant class III protein deacetylases
BJ North, B Schwer, N Ahuja, B Marshall, E Verdin
Methods 36 (4), 338-345, 2005
Functional analysis of Cullin 3 E3 ligases in tumorigenesis
J Cheng, J Guo, Z Wang, BJ North, K Tao, X Dai, W Wei
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1869 (1), 11-28, 2018
The system can't perform the operation now. Try again later.
Articles 1–20