The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase BJ North, BL Marshall, MT Borra, JM Denu, E Verdin Molecular cell 11 (2), 437-444, 2003 | 1920 | 2003 |
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function NL Price, AP Gomes, AJY Ling, FV Duarte, A Martin-Montalvo, BJ North, ... Cell metabolism 15 (5), 675-690, 2012 | 1695 | 2012 |
The intersection between aging and cardiovascular disease BJ North, DA Sinclair Circulation research 110 (8), 1097-1108, 2012 | 1590 | 2012 |
Sirtuins: Sir2-related NAD-dependent protein deacetylases BJ North, E Verdin Genome biology 5, 1-12, 2004 | 734 | 2004 |
The human silent information regulator (Sir) 2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase B Schwer, BJ North, RA Frye, M Ott, E Verdin The Journal of cell biology 158 (4), 647-657, 2002 | 701 | 2002 |
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase N Ahuja, B Schwer, S Carobbio, D Waltregny, BJ North, V Castronovo, ... Journal of Biological Chemistry 282 (46), 33583-33592, 2007 | 509 | 2007 |
SIRT1 regulates HIV transcription via Tat deacetylation S Pagans, A Pedal, BJ North, K Kaehlcke, BL Marshall, A Dorr, ... PLoS biology 3 (2), e41, 2005 | 433 | 2005 |
Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis BJ North, E Verdin PloS one 2 (8), e784, 2007 | 373 | 2007 |
Selective Sirt2 inhibition by ligand-induced rearrangement of the active site T Rumpf, M Schiedel, B Karaman, C Roessler, BJ North, A Lehotzky, ... Nature communications 6 (1), 6263, 2015 | 289 | 2015 |
Histone deacetylase HDAC8 associates with smooth muscle α‐actin and is essential for smooth muscle cell contractility D Waltregny, W Glénisson, SL Tran, BJ North, E Verdin, A Colige, ... The FASEB journal 19 (8), 966-968, 2005 | 268 | 2005 |
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy Y Gao, NT Nihira, X Bu, C Chu, J Zhang, A Kolodziejczyk, Y Fan, NT Chan, ... Nature cell biology 22 (9), 1064-1075, 2020 | 260 | 2020 |
SIRT 2 induces the checkpoint kinase BubR1 to increase lifespan BJ North, MA Rosenberg, KB Jeganathan, AV Hafner, S Michan, J Dai, ... The EMBO journal 33 (13), 1438-1453, 2014 | 253 | 2014 |
Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation BJ North, E Verdin Journal of Biological Chemistry 282 (27), 19546-19555, 2007 | 186 | 2007 |
Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues D Waltregny, L De Leval, W Glénisson, SL Tran, BJ North, A Bellahcène, ... The American journal of pathology 165 (2), 553-564, 2004 | 177 | 2004 |
Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling B Beirowski, J Gustin, SM Armour, H Yamamoto, A Viader, BJ North, ... Proceedings of the National Academy of Sciences 108 (43), E952-E961, 2011 | 173 | 2011 |
TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling B Wang, Z Jie, D Joo, A Ordureau, P Liu, W Gan, J Guo, J Zhang, BJ North, ... Nature 545 (7654), 365-369, 2017 | 167 | 2017 |
The emerging roles of protein homeostasis‐governing pathways in Alzheimer's disease J Cheng, BJ North, T Zhang, X Dai, K Tao, J Guo, W Wei Aging cell 17 (5), e12801, 2018 | 112 | 2018 |
Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells D Waltregny, B North, F Van Mellaert, J de Leval, E Verdin, V Castronovo European journal of histochemistry 48 (3), 273-290, 2004 | 82 | 2004 |
Preparation of enzymatically active recombinant class III protein deacetylases BJ North, B Schwer, N Ahuja, B Marshall, E Verdin Methods 36 (4), 338-345, 2005 | 81 | 2005 |
Functional analysis of Cullin 3 E3 ligases in tumorigenesis J Cheng, J Guo, Z Wang, BJ North, K Tao, X Dai, W Wei Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1869 (1), 11-28, 2018 | 76 | 2018 |