New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease I Zueva, J Dias, S Lushchekina, V Semenov, M Mukhamedyarov, ... Neuropharmacology 155, 131-141, 2019 | 79 | 2019 |
Structure-based optimization of nonquaternary reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents G Santoni, J de Sousa, E de La Mora, J Dias, L Jean, JL Sussman, ... Journal of medicinal chemistry 61 (17), 7630-7639, 2018 | 54 | 2018 |
Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase J Renou, J Dias, G Mercey, T Verdelet, C Rousseau, AJ Gastellier, ... RSC advances 6 (22), 17929-17940, 2016 | 46 | 2016 |
Association of mitochondrial Lysyl-tRNA synthetase with HIV-1 GagPol involves catalytic domain of the synthetase and transframe and integrase domains of Pol L Kobbi, G Octobre, J Dias, M Comisso, M Mirande Journal of molecular biology 410 (5), 875-886, 2011 | 36 | 2011 |
Small-angle X-ray solution scattering study of the multi-aminoacyl-tRNA synthetase complex reveals an elongated and multi-armed particle J Dias, L Renault, J Pérez, M Mirande Journal of Biological Chemistry 288 (33), 23979-23989, 2013 | 35 | 2013 |
Thyroid hormone controls carnitine status through modifications of γ-butyrobetaine hydroxylase activity and gene expression S Galland, B Georges, F Le Borgne, G Conductier, J Viana Dias, ... Cellular and Molecular Life Sciences CMLS 59, 540-545, 2002 | 35 | 2002 |
An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary … AG Calas, J Dias, C Rousseau, M Arboléas, M Touvrey-Loiodice, ... Chemico-biological interactions 267, 11-16, 2017 | 27 | 2017 |
Insights into the Regulation of the Ryanodine Receptor: Differential Effects of Mg2+ and Ca2+ on ATP Binding JM Dias, C Szegedi, I Jóna, PD Vogel Biochemistry 45 (31), 9408-9415, 2006 | 27 | 2006 |
Activation of human mitochondrial lysyl-tRNA synthetase upon maturation of its premitochondrial precursor J Dias, G Octobre, L Kobbi, M Comisso, S Flisiak, M Mirande Biochemistry 51 (4), 909-916, 2012 | 21 | 2012 |
From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series A Meden, D Knez, X Brazzolotto, F Nachon, J Dias, J Svete, J Stojan, ... European journal of medicinal chemistry 234, 114248, 2022 | 18 | 2022 |
Efficacy assessment of an uncharged reactivator of nop-inhibited acetylcholinesterase based on tetrahydroacridine pyridine-aldoxime hybrid in mouse compared to pralidoxime AG Calas, AS Hanak, N Jaffré, A Nervo, J Dias, C Rousseau, ... Biomolecules 10 (6), 858, 2020 | 17 | 2020 |
Effects of small molecule modulators on ATP binding to skeletal ryanodine receptor JM Dias, PD Vogel The Protein Journal 28, 240-246, 2009 | 17 | 2009 |
Characteristics of L-carnitine import into heart cells C Rigault, JV Dias, J Demarquoy, F Le Borgne Biochimie 90 (3), 542-546, 2008 | 17 | 2008 |
Discovery of multifunctional anti-Alzheimer’s agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters A Pasieka, D Panek, J Jończyk, J Godyń, N Szałaj, G Latacz, J Tabor, ... European Journal of Medicinal Chemistry 218, 113397, 2021 | 15 | 2021 |
A new class of Bi-and trifunctional sugar oximes as antidotes against organophosphorus poisoning O Da Silva, N Probst, C Landry, AS Hanak, P Warnault, C Coisne, ... Journal of Medicinal Chemistry 65 (6), 4649-4666, 2022 | 12 | 2022 |
Fine-tuning the biological profile of multitarget mitochondriotropic antioxidants for neurodegenerative diseases D Chavarria, O Da Silva, S Benfeito, S Barreiro, J Garrido, F Cagide, ... Antioxidants 10 (2), 329, 2021 | 10 | 2021 |
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase L Gorecki, V Hepnarova, JZ Karasova, M Hrabinova, C Courageux, J Dias, ... Archives of Toxicology 95, 985-1001, 2021 | 9 | 2021 |
Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening JA Miles, JS Kapure, GS Deora, C Courageux, A Igert, J Dias, ... Bioorganic & Medicinal Chemistry Letters 30 (24), 127609, 2020 | 7 | 2020 |
Chemoselective Hydrogenation of 6‐Alkynyl‐3‐fluoro‐2‐pyridinaldoximes: Access to First‐in‐Class 6‐Alkyl‐3‐Fluoro‐2‐pyridinaldoxime Scaffolds as New Reactivators of Sarin … J Yerri, J Dias, MR Nimmakayala, F Razafindrainibe, C Courageux, ... Chemistry–A European Journal 26 (65), 15035-15044, 2020 | 7 | 2020 |
Characterization of association of human mitochondrial lysyl-tRNA synthetase with HIV-1 Pol and tRNA3Lys F Khoder-Agha, JM Dias, M Comisso, M Mirande BMC biochemistry 19, 1-10, 2018 | 7 | 2018 |