The amipurimycin and miharamycin biosynthetic gene clusters: unraveling the origins of 2-aminopurinyl peptidyl nucleoside antibiotics AJ Romo, T Shiraishi, H Ikeuchi, GM Lin, Y Geng, YH Lee, PH Liem, T Ma, ... Journal of the American Chemical Society 141 (36), 14152-14159, 2019 | 26 | 2019 |
S-Adenosylmethionine: more than just a methyl donor YH Lee, D Ren, B Jeon, H Liu Natural product reports 40 (9), 1521-1549, 2023 | 14 | 2023 |
Biosynthesis of Oxetanocin-A Includes a B12-Dependent Radical SAM Enzyme That Can Catalyze both Oxidative Ring Contraction and the Demethylation of SAM A Zhong, YH Lee, Y Liu, H Liu Biochemistry 60 (7), 537-546, 2021 | 14 | 2021 |
Radical S-Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S YH Lee, X Hou, R Chen, J Feng, X Liu, MW Ruszczycky, JM Gao, B Wang, ... Journal of the American Chemical Society 144 (10), 4478-4486, 2022 | 9 | 2022 |
Characterization of the oxazinomycin biosynthetic pathway revealing the key role of a nonheme iron-dependent mono-oxygenase D Ren, YH Lee, SA Wang, H Liu Journal of the American Chemical Society 144 (24), 10968-10977, 2022 | 8 | 2022 |
Two radical SAM enzymes are necessary and sufficient for the in vitro production of the oxetane nucleoside antiviral agent albucidin PH Fan, Y Geng, AJ Romo, A Zhong, J Zhang, YC Yeh, YH Lee, H Liu Angewandte Chemie 134 (42), e202210362, 2022 | 5 | 2022 |
Changing Fates of the Substrate Radicals Generated in the Active Sites of the B12-Dependent Radical SAM Enzymes OxsB and AlsB YH Lee, YC Yeh, PH Fan, A Zhong, MW Ruszczycky, H Liu Journal of the American Chemical Society 145 (6), 3656-3664, 2023 | 4 | 2023 |
Reconstitution of the Final Steps in the Biosynthesis of Valanimycin Reveals the Origin of Its Characteristic Azoxy Moiety Z Zheng, J Xiong, J Bu, D Ren, YH Lee, YC Yeh, CI Lin, R Parry, Y Guo, ... Angewandte Chemie 136 (1), e202315844, 2024 | 2 | 2024 |
Studies of GenK and OxsB, two B12-dependent radical SAM enzymes involved in natural product biosynthesis YH Lee, H Liu Methods in enzymology 669, 71-90, 2022 | 1 | 2022 |
Twitch Radical S‐adenosyl‐l‐methionine Alcohol Dehydrogenases Z Zheng, YH Lee, MW Ruszczycky, R Ushimaru, HW Liu Encyclopedia of Inorganic and Bioinorganic Chemistry, 1-14, 2024 | | 2024 |
BIOSYNTHETIC STUDIES OF OXETANE-CONTAINING SUGAR NUCLEOSIDE NATURAL PRODUCT ALBUCIDIN PH Fan, Y Geng, A Romo, A Zhong, J Zhang, YC Yeh, YH Lee, H Liu 4th International Conference on Natural Product Discovery and Development in …, 2023 | | 2023 |
Biosynthesis of Oxetanocin-A Includes a B₁₂-Dependent Radical SAM Enzyme That Can Catalyze both Oxidative Ring Contraction and the Demethylation of SAM A Zhong, YH Lee, Y Liu, H Liu | | 2021 |