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Elany Barbosa Silva
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2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation
MV de Oliveira Cardoso, LRP de Siqueira, EB da Silva, LB Costa, ...
European Journal of Medicinal Chemistry 86, 48-59, 2014
1172014
Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death
EB da Silva, DAO e Silva, AR Oliveira, CH da Silva Mendes, ...
European journal of medicinal chemistry 130, 39-50, 2017
532017
Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification
SFP Braga, LC Martins, EB da Silva, PAS Júnior, SMF Murta, ...
Bioorganic & medicinal chemistry 25 (6), 1889-1900, 2017
462017
Small-molecule thioesters as SARS-CoV-2 main protease inhibitors: enzyme inhibition, structure–activity relationships, antiviral activity, and X-ray structure determination
T Pillaiyar, P Flury, N Krüger, H Su, L Schäkel, E Barbosa Da Silva, ...
Journal of Medicinal Chemistry 65 (13), 9376-9395, 2022
432022
Computer-aided design of 1, 4-naphthoquinone-based inhibitors targeting cruzain and rhodesain cysteine proteases
LR Silva, AS Guimaraes, J do Nascimento, IJ do Santos Nascimento, ...
Bioorganic & Medicinal Chemistry 41, 116213, 2021
372021
Trypanosomal cysteine peptidases: target validation and drug design strategies
EB da Silva, GA do Nascimento Pereira, RS Ferreira
Comprehensive analysis of parasite biology: From metabolism to drug …, 2016
272016
Phthaloyl amino acids as anti-inflammatory and immunomodulatory prototypes
ACL Leite, FF Barbosa, MVO Cardoso, DRM Moreira, LCD Coêlho, ...
Medicinal Chemistry Research 23, 1701-1708, 2014
252014
Discovery and characterization of trypanocidal cysteine protease inhibitors from the ‘malaria box’
GAN Pereira, EB da Silva, SFP Braga, PG Leite, LC Martins, RP Vieira, ...
European journal of medicinal chemistry 179, 765-778, 2019
242019
Structure-Based Optimization of Quinazolines as Cruzain and TbrCATL Inhibitors
E Barbosa da Silva, DA Rocha, IS Fortes, W Yang, L Monti, ...
Journal of Medicinal Chemistry 64 (17), 13054-13071, 2021
232021
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2
LH Santos, T Kronenberger, RG Almeida, EB Silva, REO Rocha, ...
Journal of Chemical Information and Modeling 62 (24), 6553-6573, 2022
222022
2-(phenylthio) ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity
MV de Oliveira Cardoso, GB de Oliveira Filho, LRP de Siqueira, ...
European Journal of Medicinal Chemistry 180, 191-203, 2019
192019
Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design
E Barbosa da Silva, E Dall, P Briza, H Brandstetter, RS Ferreira
Acta Crystallographica Section F: Structural Biology Communications 75 (6 …, 2019
182019
Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against Trypanosoma cruzi
E Barbosa Da Silva, V Sharma, L Hernandez-Alvarez, AH Tang, A Stoye, ...
Journal of Medicinal Chemistry 65 (5), 4255-4269, 2022
152022
Sales Júnior
SFP Braga, LC Martins, EB da Silva
PA, 0
12
Oliveira e Silva D, Oliveira A, da Silva Mendes C, dos Santos T, da Silva A, et al. Design and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which …
E da Silva
European Journal of Medicinal Chemistry 130, 39-50, 2017
72017
From rational design to serendipity: discovery of novel thiosemicarbazones as potent trypanocidal compounds
SFP Braga, VC Santos, RP Vieira, EB da Silva, L Monti, SH Krake, ...
European Journal of Medicinal Chemistry 244, 114876, 2022
62022
Oliveira e Silva DA, Oliveira AR, da Silva Mendes CH, dos Santos TAR, da Silva AC, de Castro MCA, Ferreira RS, Moreira DRM, Cardoso MV de O, de Simone CA, Pereira VRA, Leite ACL
EB Da Silva
Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles …, 2017
62017
Identification of Leucinostatins from Ophiocordyceps sp. as Antiparasitic Agents against Trypanosoma cruzi
JA Bernatchez, YS Kil, E Barbosa da Silva, D Thomas, LI McCall, ...
ACS omega 7 (9), 7675-7682, 2022
52022
CAB; Bernhardt, PV; Leite, ACL 2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation
M Cardoso, L Siqueira, EBD Silva, LB Costa, MZ Hernandes, MM Rabello, ...
Eur. J. Med. Chem 86, 48-59, 2014
42014
Beneficiamento e caracterização de quartzo para obtenção de silício grau metalúrgico
LGL Soares, EB da Silva, FMS Garrido, F da Silva, RS Amado, ...
HOLOS 5, 3-10, 2012
42012
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Articles 1–20