The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction X Huang, CS Atwood, MA Hartshorn, G Multhaup, LE Goldstein, ... Biochemistry 38 (24), 7609-7616, 1999 | 1417 | 1999 |
Cu (II) potentiation of Alzheimer Aβ neurotoxicity: correlation with cell-free hydrogen peroxide production and metal reduction X Huang, MP Cuajungco, CS Atwood, MA Hartshorn, JDA Tyndall, ... Journal of Biological Chemistry 274 (52), 37111-37116, 1999 | 1003 | 1999 |
Zinc metabolism in the brain: relevance to human neurodegenerative disorders MP Cuajungco, GJ Lees Neurobiology of disease 4 (3-4), 137-169, 1997 | 746 | 1997 |
Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia SA Slaugenhaupt, A Blumenfeld, SP Gill, M Leyne, J Mull, MP Cuajungco, ... The American Journal of Human Genetics 68 (3), 598-605, 2001 | 665 | 2001 |
Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc MP Cuajungco, LE Goldstein, A Nunomura, MA Smith, JT Lim, CS Atwood, ... Journal of Biological Chemistry 275 (26), 19439-19442, 2000 | 555 | 2000 |
Zinc takes the center stage: its paradoxical role in Alzheimer’s disease MP Cuajungco, KY Fagét Brain Research Reviews 41 (1), 44-56, 2003 | 332 | 2003 |
Metal chelation as a potential therapy for Alzheimer's disease MP Cuajungco, KY Faget, X Huang, RE Tanzi, AI Bush Annals of the New York Academy of Sciences 920 (1), 292-304, 2000 | 277 | 2000 |
Zinc and Alzheimer's disease: is there a direct link? MP Cuajungco, GJ Lees Brain research reviews 23 (3), 219-236, 1997 | 225 | 1997 |
PACSINs bind to the TRPV4 cation channel: PACSIN 3 modulates the subcellular localization of TRPV4 MP Cuajungco, C Grimm, K Oshima, D D'hoedt, B Nilius, ... Journal of Biological Chemistry 281 (27), 18753-18762, 2006 | 208 | 2006 |
Alzheimer's disease, β-amyloid protein and zinc X Huang, MP Cuajungco, CS Atwood, RD Moir, RE Tanzi, AI Bush The Journal of nutrition 130 (5), 1488S-1492S, 2000 | 196 | 2000 |
Rescue of a human mRNA splicing defect by the plant cytokinin kinetin SA Slaugenhaupt, J Mull, M Leyne, MP Cuajungco, SP Gill, MM Hims, ... Human molecular genetics 13 (4), 429-436, 2004 | 170 | 2004 |
A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse C Grimm, MP Cuajungco, AFJ van Aken, M Schnee, S Jörs, CJ Kros, ... Proceedings of the National Academy of Sciences 104 (49), 19583-19588, 2007 | 168 | 2007 |
Zinc and excitotoxic brain injury: a new model CJ Frederickson, W Maret, MP Cuajungco The Neuroscientist 10 (1), 18-25, 2004 | 161 | 2004 |
Tissue-specific reduction in splicing efficiency of IKBKAP due to the major mutation associated with familial dysautonomia MP Cuajungco, M Leyne, J Mull, SP Gill, W Lu, D Zagzag, FB Axelrod, ... The American Journal of Human Genetics 72 (3), 749-758, 2003 | 156 | 2003 |
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3 D D'hoedt, G Owsianik, J Prenen, MP Cuajungco, C Grimm, S Heller, ... Journal of Biological Chemistry 283 (10), 6272-6280, 2008 | 151 | 2008 |
Nitric oxide generators produce accumulation of chelatable zinc in hippocampal neuronal perikarya MP Cuajungco, GJ Lees Brain research 799 (1), 118-129, 1998 | 142 | 1998 |
Small molecule activators of TRPML3 C Grimm, S Jörs, SA Saldanha, AG Obukhov, B Pan, K Oshima, ... Chemistry & biology 17 (2), 135-148, 2010 | 139 | 2010 |
Zinc dyshomeostasis is linked with the loss of mucolipidosis IV-associated TRPML1 ion channel JL Eichelsdoerfer, JA Evans, SA Slaugenhaupt, MP Cuajungco Journal of biological chemistry 285 (45), 34304-34308, 2010 | 119 | 2010 |
Abnormal accumulation of human transmembrane (TMEM)-176A and 176B proteins is associated with cancer pathology MP Cuajungco, W Podevin, VK Valluri, Q Bui, VH Nguyen, K Taylor Acta histochemica 114 (7), 705-712, 2012 | 96 | 2012 |
The tissue-specific expression of TRPML2 (MCOLN-2) gene is influenced by the presence of TRPML1 MA Samie, C Grimm, JA Evans, C Curcio-Morelli, S Heller, ... Pflügers Archiv-European Journal of Physiology 459, 79-91, 2009 | 96 | 2009 |